{{Short description|Mammalian protein found in humans}} {{infobox protein | Name = caspase 5, apoptosis-related cysteine peptidase | caption = | image = | width = 240px | HGNCid = 1506 | Symbol = CASP5 | AltSymbols = ICE(rel)III, ICH3 | EntrezGene = 838 | OMIM = 602665 | RefSeq = NM_004347 | UniProt = P51878 | PDB = | ECnumber = 3.4.22.58 | Chromosome = 11 | Arm = q | Band = 22.2-q22.3 | LocusSupplementaryData = }}

thumb | right | Intrinsic and Extrinsic pathways of caspase activation '''Caspase 5''' is an enzyme that proteolytically cleaves other proteins at an aspartic acid residue, and belongs to a family of cysteine proteases called caspases. It is an inflammatory caspase, along with caspase 1, caspase 4 and the murine caspase 4 homolog caspase 11, and has a role in the immune system.<ref>{{cite journal |vauthors=Martinon F, Tschopp J |title=Inflammatory caspases and inflammasomes: master switches of inflammation |journal=Cell Death Differ. |volume=14 |issue=1 |pages=10–22 |year=2007 |pmid=16977329 |doi=10.1038/sj.cdd.4402038|doi-access=free }}</ref>

==See also== * The Proteolysis Map * Caspase

==References== <references/>

==External links== * The MEROPS online database for peptidases and their inhibitors: [https://archive.today/20121223124946/http://merops.sanger.ac.uk/cgi-bin/merops.cgi?id=C14.008 C14.008]

{{Cysteine proteases}} {{Enzymes}} {{Portal bar|Biology|border=no}}

Category:EC 3.4.22 Category:Caspases

{{gene-11-stub}}