TMED2

{{Short description|Protein-coding gene}} {{Infobox_gene}} '''Transmembrane emp24 domain-containing protein 2''' is a protein that in humans is encoded by the ''TMED2'' gene.<ref name="pmid8663407">{{cite journal | vauthors = Blum R, Feick P, Puype M, Vandekerckhove J, Klengel R, Nastainczyk W, Schulz I | title = Tmp21 and p24A, two type I proteins enriched in pancreatic microsomal membranes, are members of a protein family involved in vesicular trafficking | journal = The Journal of Biological Chemistry | volume = 271 | issue = 29 | pages = 17183–9 | date = July 1996 | pmid = 8663407 | doi = 10.1074/jbc.271.29.17183 | doi-access = free }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: TMED2 transmembrane emp24 domain trafficking protein 2| url = https://www.ncbi.nlm.nih.gov/gene?Db=gene&Cmd=ShowDetailView&TermToSearch=10959}}</ref>

== Interactions ==

TMED2 has been shown to interact with GORASP1<ref name=pmid11739402>{{cite journal | vauthors = Barr FA, Preisinger C, Kopajtich R, Körner R | title = Golgi matrix proteins interact with p24 cargo receptors and aid their efficient retention in the Golgi apparatus | journal = The Journal of Cell Biology | volume = 155 | issue = 6 | pages = 885–91 | date = December 2001 | pmid = 11739402 | pmc = 2150891 | doi = 10.1083/jcb.200108102 }}</ref> and GORASP2.<ref name=pmid11739402/>

== References == {{Reflist}}

== Further reading == {{Refbegin | 2}} * {{cite journal | vauthors = Fiedler K, Veit M, Stamnes MA, Rothman JE | title = Bimodal interaction of coatomer with the p24 family of putative cargo receptors | journal = Science | volume = 273 | issue = 5280 | pages = 1396–9 | date = September 1996 | pmid = 8703076 | doi = 10.1126/science.273.5280.1396 | bibcode = 1996Sci...273.1396F | s2cid = 13159384 }} * {{cite journal | vauthors = Gommel D, Orci L, Emig EM, Hannah MJ, Ravazzola M, Nickel W, Helms JB, Wieland FT, Sohn K | title = p24 and p23, the major transmembrane proteins of COPI-coated transport vesicles, form hetero-oligomeric complexes and cycle between the organelles of the early secretory pathway | journal = FEBS Letters | volume = 447 | issue = 2–3 | pages = 179–85 | date = March 1999 | pmid = 10214941 | doi = 10.1016/S0014-5793(99)00246-X | s2cid = 41832392 | doi-access = free }} * {{cite journal | vauthors = Majoul I, Straub M, Hell SW, Duden R, Söling HD | title = KDEL-cargo regulates interactions between proteins involved in COPI vesicle traffic: measurements in living cells using FRET | journal = Developmental Cell | volume = 1 | issue = 1 | pages = 139–53 | date = July 2001 | pmid = 11703931 | doi = 10.1016/S1534-5807(01)00004-1 | doi-access = free }} * {{cite journal | vauthors = Barr FA, Preisinger C, Kopajtich R, Körner R | title = Golgi matrix proteins interact with p24 cargo receptors and aid their efficient retention in the Golgi apparatus | journal = The Journal of Cell Biology | volume = 155 | issue = 6 | pages = 885–91 | date = December 2001 | pmid = 11739402 | pmc = 2150891 | doi = 10.1083/jcb.200108102 }} * {{cite journal | vauthors = Breuza L, Halbeisen R, Jenö P, Otte S, Barlowe C, Hong W, Hauri HP | title = Proteomics of endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membranes from brefeldin A-treated HepG2 cells identifies ERGIC-32, a new cycling protein that interacts with human Erv46 | journal = The Journal of Biological Chemistry | volume = 279 | issue = 45 | pages = 47242–53 | date = November 2004 | pmid = 15308636 | doi = 10.1074/jbc.M406644200 | doi-access = free }} * {{cite journal | vauthors = Chen F, Hasegawa H, Schmitt-Ulms G, Kawarai T, Bohm C, Katayama T, Gu Y, Sanjo N, Glista M, Rogaeva E, Wakutani Y, Pardossi-Piquard R, Ruan X, Tandon A, Checler F, Marambaud P, Hansen K, Westaway D, St George-Hyslop P, Fraser P | title = TMP21 is a presenilin complex component that modulates gamma-secretase but not epsilon-secretase activity | journal = Nature | volume = 440 | issue = 7088 | pages = 1208–12 | date = April 2006 | pmid = 16641999 | doi = 10.1038/nature04667 | bibcode = 2006Natur.440.1208C | s2cid = 4349251 }} * {{cite journal | vauthors = Luo W, Wang Y, Reiser G | title = p24A, a type I transmembrane protein, controls ARF1-dependent resensitization of protease-activated receptor-2 by influence on receptor trafficking | journal = The Journal of Biological Chemistry | volume = 282 | issue = 41 | pages = 30246–55 | date = October 2007 | pmid = 17693410 | doi = 10.1074/jbc.M703205200 | doi-access = free }} {{Refend}}