{{Short description|American pathologist (1929–1999)}} {{Infobox person | name = Russell Ross | image = Russell Ross.jpg | alt = | caption = Ross in 1994 | birth_name = | birth_date = May 25, 1929 | birth_place = St. Augustine, Florida | death_date = {{death date and age|1999|3|18|1929|5|25}} | death_place = Seattle, Washington | other_names = | occupation = professor of pathology | known_for = "Response to Injury Hypothesis" for atherosclerosis<ref>{{cite news|author=Nagourney, Eric|title=Russell Ross, 69, Pioneer in Artery Research|date=22 March 1999|newspaper=NY Times|url=https://www.nytimes.com/1999/03/22/us/russell-ross-69-pioneer-in-artery-research.html}}</ref> }} '''Russell Ross''' (1929–1999) was an American professor of pathology, known for research on the pathogenesis of atherosclerosis.<ref name=ObitAJP>{{cite journal|author=Fausto, Nelson|title=Obituary. Russell Ross|journal=American Journal of Pathology|date=May 1999|volume=154|issue=5|pages=1309–1310|pmc=1866597|doi=10.1016/s0002-9440(10)65382-5|pmid=10329581}}</ref><ref>{{cite book|editor=Wick, Georg|editor2=Grundtman, Cecilia|title=Inflammation and Atherosclerosis|author=Nieto, F. J.|chapter=Historical Reflections on the Inflammatory Aspects of Atherosclerosis|pages=1–17|publisher=Springer Science & Business Media|year=2011|isbn=9783709103388|chapter-url=https://books.google.com/books?id=wvN8seSPBVMC&pg=PA1}}</ref>
==Education and career== Russell Ross grew up in Jacksonville, Florida and graduated from Cornell University in 1951 before earning a degree in dentistry from Columbia University College of Dental Medicine in 1955. In 1958 he became a doctoral student and received a PhD in experimental pathology from the University of Washington at Seattle in 1962. At the University of Washington at Seattle, Dr. Ross joined the faculty of the University of Washington School of Medicine and was appointed Professor of Pathology in 1969. He served as chair of the Department of Pathology and helped to create an important center for research and medical training in vascular biology and pathology.
Ross was awarded a Guggenheim Fellowship for the academic year 1966–1967, which he spent studying cell culture at the Strangeways Research Laboratory.<ref>{{cite news|title=Dr. Russell Ross Made Important Discoveries About Atherosclerosis|newspaper=The Seattle Times|date=21 March 1999|url=https://archive.seattletimes.com/archive/19990321/2950692/dr-russell-ross-made-important-discoveries-about-atherosclerosis}}</ref> He received many awards and honors and was the author or co-author of 385 published papers and book chapters. Russ was a co-editor, with Valentín Fuster and Eric J. Topol, of the textbook ''Atherosclerosis and Coronary Artery Disease''.<ref>{{cite book|editor=Fuster, Valentín |editor2=Topol, Eric J.|editor3=Nabel, Elizabeth G.|title=Atherothrombosis and Coronary Artery Disease|publisher=Lippincott Williams & Wilkins|year=2005|page=xxv of Preface|isbn=9780781735834|url=https://books.google.com/books?id=1WifwPEsKQMC&pg=PR25}}</ref> He was elected a fellow of the American Academy of Arts and Sciences and a member of the Institute of Medicine of the National Academy of Sciences. He served a term as president of the American Society for Investigative Pathology and in 1992 received the Society's Rous-Whipple Award. He was a member of the editorial boards of more than 20 scientific journals.
{{blockquote|... Russ made notable contributions to the understanding of the pathogenesis of atherosclerosis. Together with John Glomset, Russ formulated the "Response to Injury Hypothesis" of atherosclerosis in 1973. The hypothesis, which has been tested and modified from its original formulation, has had a profound impact on atherosclerosis research and vascular biology. Instead of a site for passive accumulation of blood lipids, the artery wall is now seen as a living, reactive tissue capable of mounting an inflammatory response. Russ and his colleagues are credited with many major discoveries, among them the work with Dr. Daniel Bowen-Pope on the identification of platelet-derived growth factor receptors. More recently Russ's laboratory has done studies on the early diagnosis and evolution of atherosclerotic lesions in humans, primates, and various animal models. Dr. Elaine Raines, Russ's close collaborator and associate for 26 years, was a major participant in most of the work from the laboratory.<ref name=ObitAJP/>}}
==Personal life== He participated in many community activities and was a member of the board of directors for the Seattle Symphony.<ref name="Nature 1999">{{cite web |last1=Libby |first1=Peter |title=Russell Ross 1929–1999 |url=https://www.nature.com/articles/nm0599_475 |website=Nature Medicine |pages=475–475 |language=en |doi=10.1038/8351 |date=May 1999}}</ref> Upon his death he was survived by his wife, a son, and a daughter.
==See also== *Chronic endothelial injury hypothesis
==References== <references />
{{Authority control}}
{{DEFAULTSORT:Ross, Russell}} Category:1929 births Category:1999 deaths Category:American pathologists Category:Cornell University alumni Category:Columbia University College of Dental Medicine alumni Category:University of Washington alumni Category:University of Washington faculty Category:People from St. Augustine, Florida Category:Fellows of the American Academy of Arts and Sciences Category:Members of the National Academy of Medicine Category:20th-century American people