{{Short description|American researcher (1926-2019)}} {{Infobox person | name = | honorific_suffix = | image = | alt = | caption = | birth_date = August 28, 1926 | birth_place = Reno, Nevada | death_date = January 2019 | death_place = | other_names = Lazar; Hosteen Nez | alma_mater = | occupation = Mining engineer | years_active = | organization = | known_for = Psychedelic drug research, development and research on 2C-D and TWEETIOs as "smart drugs" | notable_works = | website = }}

'''Darrell Lemaire''' (August 28, 1926 – January 2019) was an American mining engineer and psychedelic drug chemist.<ref name="Morris2016-S01E06" /><ref name="Vice2016">{{cite web|url=https://www.vice.com/en/article/tonight-on-viceland-hamiltons-pharmacopeia-lizard-school/ |title=Inside the Lazy Lizard School of Hedonism |publisher=Vice News |date=2016-12-07 |access-date=2016-12-12}}</ref>

==Life and work== Lemaire was born in Reno, Nevada on August 28, 1926.<ref>{{cite web|url=https://erowid.org/culture/characters/lemaire_darrell/|title=Erowid Character Vaults - Darrell Lemaire|website=Erowid|date=2016-08-02|accessdate=2017-12-14}}</ref> He spent two years in the U.S. Navy (1944–46). He then earned a B.S. in chemistry from the University of Nevada in 1953<ref>https://unr.dgicloud.com/57285</ref>, followed by his master's in metallurgical engineering from Mackay School of Mines (1954<ref>https://unr.dgicloud.com/57286</ref>).{{Citation needed|date=November 2025}}

While working at a Uranium processing plant in Arizona, working closely with Navajo natives, Lemaire discovered peyote, and became intensely interested in manufacturing and testing a variety of psychoactive substances. Lemaire used pseudonyms "Hosteen Nez" and "Lazar" in order to publish a pamphlet on some of his findings regarding 2C-D.<ref>{{cite web|url=https://archives.lib.purdue.edu/agents/people/438 |title=Lemaire, Darrell | publisher=Purdue University Archives and Special Collections | accessdate=2023-06-04}}</ref> Lemaire also developed the TWEETIO series of psychedelics, including compounds such as 2CD-5EtO.<ref name="Erowid-Lemaire">{{cite web | title=Erowid Darrell Lemaire Vault | website=erowid.org | url=https://erowid.org/culture/characters/lemaire_darrell/lemaire_darrell.shtml | access-date=14 November 2025}}</ref><ref name="Morris2016-S01E06" /><ref name="Nez2010">{{cite book | author = Hosteen Nez (Darrell Lemaire) | chapter = Notes About Psychoactive Compounds | pages = 201–207 | editor1-last = Targ | editor1-first = Russell | editor2-last = Radin | editor2-first = Dean | title = Radiant Minds: Scientists Explore the Dimensions of Consciousness | publisher = Millay | date = 2010 | isbn = 978-0-615-29633-3 | url = https://books.google.com/books?id=bF-jcQAACAAJ | chapter-url = https://erowid.org/culture/characters/lemaire_darrell/lemaire_darrell_article1.pdf}}</ref><ref name="LazarNez1990">{{citation | author1 = Lazar (Darrell Lemaire) | author2 = Hosteen Nez | title = Certain Exotic Transmitters as Smart Pills or Compounds that Increase the Capacity for Mental Work in Humans: A Story About LAZAR as Told by Hosteen Nez | edition = 2 | date = 1990 | url = https://erowid.org/chemicals/2cd/2cd_smartpills1.pdf | archive-url = https://web.archive.org/web/20010709231503/http://www.erowid.org/chemicals/2cd/2cd_smartpills1.shtml | archive-date = 9 July 2001}}</ref> Lemaire was the mentor of the psychedelic clandestine chemist Casey Hardison.<ref name="Morris2016-S01E06" /><ref name="Hardison2007">{{cite journal | last=Hardison | first=Casey | title=A brief history and motivation of an entheogenic chemist | journal=Drugs and Alcohol Today | volume=7 | issue=2 | date=1 July 2007 | issn=1745-9265 | doi=10.1108/17459265200700013 | pages=26–31 | url=http://www.emerald.com/dat/article/7/2/26-31/102048| url-access=subscription }}</ref> Lemaire's work in the area of psychedelics was covered by Hamilton Morris in his documentary TV series ''Hamilton's Pharmacopeia'' in 2016.<ref name="Morris2016-S01E06">{{cite episode | credits = Morris H | date = 7 December 2016 | title = The Lazy Lizard School of Hedonism | series = Hamilton's Pharmacopeia | season = 1 | number = 6 | url = https://vimeo.com/546752807| publisher = Vice Media | network = Viceland}}</ref>

Lemaire has also done work involving the use of gumweed as a potential biofuel in conjunction with individuals at the University of Nevada.{{Citation needed|date=November 2025}}

He died from cancer in January 2019, at the age of 92.<ref>{{Cite web |title=Erowid Darrell Lemaire Vault |url=https://erowid.org/culture/characters/lemaire_darrell/ |access-date=2023-05-03 |website=erowid.org}}</ref>

==Publications== * {{cite journal | vauthors = Lemaire D, Jacob P, Shulgin AT | title = Ring-substituted beta-methoxyphenethylamines: a new class of psychotomimetic agents active in man | journal = J Pharm Pharmacol | volume = 37 | issue = 8 | pages = 575–577 | date = August 1985 | pmid = 2864422 | doi = 10.1111/j.2042-7158.1985.tb03072.x | url = }} * {{citation | author1 = Lazar (Darrell Lemaire) | author2 = Hosteen Nez | title = Certain Exotic Transmitters as Smart Pills or Compounds that Increase the Capacity for Mental Work in Humans: A Story About LAZAR as Told by Hosteen Nez | edition = 2 | date = 1990 | url = https://erowid.org/chemicals/2cd/2cd_smartpills1.pdf | archive-url = https://web.archive.org/web/20010709231503/http://www.erowid.org/chemicals/2cd/2cd_smartpills1.shtml | archive-date = 9 July 2001}} * {{cite book | author = Hosteen Nez (Darrell Lemaire) | chapter = Notes About Psychoactive Compounds | pages = 201–207 | editor1-last = Targ | editor1-first = Russell | editor2-last = Radin | editor2-first = Dean | title = Radiant Minds: Scientists Explore the Dimensions of Consciousness | publisher = Millay | date = 2010 | isbn = 978-0-615-29633-3 | url = https://books.google.com/books?id=bF-jcQAACAAJ | chapter-url = https://erowid.org/culture/characters/lemaire_darrell/lemaire_darrell_article1.pdf}} * ''Synthetic Methods Index'' (1986),<ref>{{cite web|url=https://archives.lib.purdue.edu/repositories/2/archival_objects/188 |date=c. 1986 |title=Darrell Lemaire papers, MSP 64 | publisher=Purdue University Archives and Special Collections | accessdate=2023-06-04}}</ref> a paper on the creation of novel psychedelic substances. * {{cite journal | author = Lazar | title = Short-Acting | journal = The Entheogen Review | volume = 10 | issue = 1 | pages = 20–23 | date = 2001 | issn = 1066-1913 | url = https://archive.org/details/TheEntheogenReviewComplete19922008/page/n999/mode/2up | archive-url = https://erowid.org/psychoactives/pharmacology/pharmacology_article3.shtml | archive-date = 31 January 2001}} * {{cite journal | author = Lazar | title = Some "High" Desert Plants | journal = The Entheogen Review | volume = 11 | issue = 1 | pages = 6–8 | date = 2002 | issn = 1066-1913 | url = https://archive.org/details/TheEntheogenReviewComplete19922008/page/n1173/mode/2up}}

==See also== * List of psychedelic chemists * 2C-D and TWEETIO (psychedelics)

==References== {{Reflist}}

==Further reading== * [https://erowid.org/characters/lemaire_darrell/lemaire_darrell.shtml Darrell Lemaire - Erowid] * [https://archives.lib.purdue.edu/agents/people/438 Lemaire, Darrell (1926) - Archives and Special Collections - Purdue University]

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Category:1926 births Category:2019 deaths Category:American mining engineers Category:Psychedelic chemists Category:Psychedelic drug researchers Category:Scientists from Reno, Nevada Category:Engineers from Nevada