'''CVAC''' may refer to:
* Carolinas-Virginia Athletic Conference, abbreviation of the former name of the Conference Carolinas, a United States collegiate athletic conference of NCAA Division II * Catawba Valley Athletic Conference, a United States high school athletic conference located in North Carolina * CVac, a prospective therapeutic vaccine for ovarian cancer * Cyclic Variations in Adaptive Conditioning, an alternative treatment for Adiposis dolorosa
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