{{chembox | verifiedrevid = 424684079 | ImageFile=Trichodermin.png | ImageSize=200px | IUPACName=12,13-Epoxytrichothec-9-en-4β-yl acetate | SystematicName=(2''R'',2′''S'',4''R'',5''S'',5a''R'',9a''R'')-5,5a,8-Trimethyl-2,3,4,5,5a,6,7,9a-octahydrospiro[<nowiki/>[2,5]methano[1]benzoxepine-10,2′-oxiran]-4-yl acetate | OtherNames= |Section1={{Chembox Identifiers | CASNo_Ref = {{cascite|correct|??}} | CASNo=4682-50-2 | Beilstein = 6868411 | ChEBI = 9688 | ChEMBL = 4463552 | ChemSpiderID = 19582 | KEGG = C09741 | UNII_Ref = {{fdacite|correct|FDA}} | UNII = WF22557W91 | PubChem=20806 | StdInChI=1S/C17H24O4/c1-10-5-6-15(3)12(7-10)21-14-8-13(20-11(2)18)16(15,4)17(14)9-19-17/h7,12-14H,5-6,8-9H2,1-4H3/t12-,13-,14-,15+,16-,17+/m1/s1 | StdInChIKey = HNEGCRMUYSKRRR-IKIFYQGPSA-N | SMILES=CC1=C[C@@H]2[C@](CC1)([C@]3([C@@H](C[C@H]([C@@]34CO4)O2)OC(=O)C)C)C }} |Section2={{Chembox Properties | Formula=C<sub>17</sub>H<sub>24</sub>O<sub>4</sub> | MolarMass=292.37 g/mol | Appearance= | Density= | MeltingPt= | BoilingPt= | Solubility= }} |Section3={{Chembox Hazards | MainHazards= | FlashPt= | AutoignitionPt = }} }}
'''Trichodermin''' is a trichothecene.<ref>{{cite journal |last1=Wei |first1=Cha-mer |last2=Hansen |first2=Bent S. |last3=Vaughan |first3=Maurice H. |last4=McLaughlin |first4=Calvin S. |title=Mechanism of Action of the Mycotoxin Trichodermin, a 12,13-Epoxytrichothecene |journal=Proceedings of the National Academy of Sciences |date=March 1974 |volume=71 |issue=3 |pages=713–717 |doi=10.1073/pnas.71.3.713 |pmid=4522785 |bibcode=1974PNAS...71..713W |doi-access=free |pmc=388083 }}</ref> It inhibits protein formation in Euchariotes.<ref>{{cite journal |last1=Carrasco |first1=L. |last2=Barbacid |first2=M. |last3=Vazquez |first3=D. |title=The trichodermin group of antibiotics, inhibitors of peptide bond formation by eukaryotic ribosomes |journal=Biochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis |date=June 1973 |volume=312 |issue=2 |pages=368–376 |doi=10.1016/0005-2787(73)90381-X |pmid=4579233 }}</ref>
==References== {{Reflist}}
Category:Trichothecenes Category:Epoxides Category:Acetate esters
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