'''Systemic administration''' is a route of administration of medication, nutrition or other substance into the circulatory system so that the entire body is affected.<ref>{{cite book|title=Hunnius Pharmazeutisches Wörterbuch|year=1998|edition=8th|publisher=Walter de Gruyter|language=German|location=Berlin|isbn=3-11-015793-4|page=1477}}</ref> Administration can take place via enteral administration (absorption of the drug through the gastrointestinal tract)<ref>{{cite web|url=http://www.britannica.com/EBchecked/topic/188838/enteral-administration|title=Enteral administration - pharmacology|author=|date=|website=britannica.com|accessdate=19 April 2018}}</ref> or parenteral administration (generally injection, infusion, or implantation).<ref>{{cite book|title=Hunnius Pharmazeutisches Wörterbuch|year=1998|edition=8th|publisher=Walter de Gruyter|language=German|location=Berlin|isbn=3-11-015793-4|pages=472, 1029}}</ref><ref name="Mutschler">{{cite book|last1=Mutschler|first1=Ernst|title=Arzneimittelwirkungen|language=German|location=Stuttgart|publisher=Wissenschaftliche Verlagsgesellschaft|year=2013|edition=10|page=8|isbn=978-3-8047-2898-1}}</ref>

Contrast with topical administration where the effect is generally local.<ref name="Mutschler" />

==References== {{reflist}}

{{Routes of administration}}

Category:Routes of administration

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