{{Short description|Proliferation of endoderm induced by the paramesonephric ducts}} {{Infobox embryology | Name = Sinus tubercle | Latin = | Image = Gray1109.png | Caption = Urogenital sinus of female human embryo of eight and a half to nine weeks old. | Image2 = | Caption2 = | System = | CarnegieStage = | Precursor = | GivesRiseTo = }}
'''Sinus tubercle''' (also known as '''sinual tubercle'''<ref name=":0">{{Citation|last=Ruchelli|first=Eduardo D.|title=Vagina|date=2011|url=https://doi.org/10.1007/978-1-4614-0019-6_17|work=Color Atlas of Fetal and Neonatal Histology|pages=195–198|editor-last=Ernst|editor-first=Linda M.|place=New York, NY|publisher=Springer|language=en|doi=10.1007/978-1-4614-0019-6_17|isbn=978-1-4614-0019-6|access-date=2021-05-27|last2=Ruchelli|first2=Eduardo D.|last3=Huff|first3=Dale S.|last4=Huff|first4=Dale S.|editor2-last=Ruchelli|editor2-first=Eduardo D.|editor3-last=Huff|editor3-first=Dale S.|url-access=subscription}}</ref> or '''Müllerian eminence''') is the proliferation of endoderm induced by the paramesonephric ducts. It is located in the developing fetus between the orifices of the mesonephric ducts on the urogenital sinus.<ref name=":0" /> The uterovaginal primoridium, which is a fusion of the caudal ends of paramesonephric ducts, contacts the dorsal wall of the urogenital sinus and, induces the formation of the sinus tubercle. This occurs in both sexes: *In the female, the mesonephric duct loses all association with the gonad and disappears. The sinus tubercle then gives rise to the sino-vaginal bulbs and, when it later becomes solid it is referred to as the vaginal plate.<ref name=":0" /> It likewise gives rise to the hymen, which eventually breaks down in most cases. * In the males, the sinus tubercle gives rise to the seminal colliculus.
==References== * {{Gray's}} *Moore Persaud, ''Medical embryology'' 2003 <references /> {{Development of urinary and reproductive systems}}
Category:Animal developmental biology Category:Embryology