{{Short description|Presence of a marker in blood}} '''Serostatus''' refers to the presence or absence of a serological marker in the blood. The presence of detectable levels of a specific marker within the serum is considered '''seropositivity''', while the absence of such levels is considered '''seronegativity'''.

==HIV/AIDS== The term serostatus is commonly used in HIV/AIDS prevention efforts. In the late 20th and early 21st centuries, social advocacy has emphasized the importance of learning one's HIV/AIDS serostatus in an effort to curtail the spread of the disease.<ref name=SAFE />

==Autoimmune disease== Researchers have investigated the effects of autoantibody serostatus on autoimmune disease presentation.<ref name=Neuromyelitis /><ref name=Rheumatoid /><ref name=Pancreatitis /> Study of seronegative patient populations has led to the identification of additional autoantibodies that could potentially help with diagnosis.<ref name=Novel /><ref name=Myasthenia />

==See also== * Seroconversion * Correlates of immunity

==References== <references> <ref name=SAFE>{{cite journal | last1=Janssen | first1=Robert S. | last2=Holtgrave | first2=David R. | last3=Valdiserri | first3=Ronald O. | last4=Shepherd | first4=Melissa | last5=Gayle | first5=Helene D. | last6=De Cock | first6=Kevin M. | display-authors=3 | date=July 2001 | title=The Serostatus Approach to Fighting the HIV Epidemic: prevention strategies for infected individuals | journal=American Journal of Public Health | publisher=American Public Health Association | volume=91 | issue=7 | pages=1019–1024 | doi=10.2105/AJPH.91.7.1019 | issn=1541-0048 | pmc=1446705 | pmid=11441723 |name-list-style=vanc}}</ref> <ref name=Neuromyelitis>{{cite journal | last1=Jarius | first1=Sven | last2=Ruprecht | first2=Klemens | last3=Wildemann | first3=Brigitte | last4=Kuempfel | first4=Tania | last5=Ringelstein | first5=Marius | last6=Geis | first6=Christian | last7=Kleiter | first7=Ingo | last8=Kleinschnitz | first8=Christoph | last9=Berthele | first9=Achim | last10=Brettschneider | first10=Johannes | last11=Hellwig | first11=Kerstin | last12=Hemmer | first12=Bernhard | last13=Linker | first13=Ralf A | last14=Lauda | first14=Florian | last15=Mayer | first15=Christoph A | last16=Tumani | first16=Hayrettin | last17=Melms | first17=Arthur | last18=Trebst | first18=Corinna | last19=Stangel | first19=Martin | last20=Marziniak | first20=Martin |last21=Hoffman | first21=Frank | last22=Schippling | first22=Sven | last23=Faiss | first23=Jurgen H | last24=Neuhaus | first24=Oliver | last25=Ettrich | first25=Barbara | last26=Zentner | first26=Christian | last27=Guthke | first27=Kersten | last28=Hofstadt-van Oy | first28=Ulrich | last29=Reuss | first29=Reinhard | last30=Pellkofer | first30=Hannah | last31=Ziemann | first31=Ulf | last32=Kern | first32=Peter | last33=Wandinger | first33=Klaus P | last34=Bergh | first34=Florian Then | last35=Boettcher | first35=Tobias | last36=Langel | first36=Stefan | last37=Liebetrau | first37=Martin | last38=Rommer | first38=Paulus S | last39=Niehaus | first39=Sabine | last40=Munch | first40=Christoph | last41=Winkelmann | first41=Alexander | last42=Zettl U | first42=Uwe K | last43=Metz | first43=Imke | last44=Veauthier | first44=Christian | last45=Sieb | first45=Jorn P | last46=Wilke | first46=Christian | last47=Hartung | first47=Hans P | last48=Aktas | first48=Orhan | last49=Paul | first49=Friedemann | display-authors=3 | date=January 2012 | title=Contrasting disease patterns in seropositive and seronegative neuromyelitis optica: A multicentre study of 175 patients | journal=Journal of Neuroinflammation | publisher=BioMed Central | volume=9 | issue=1 | pages=14 | doi=10.1186/1742-2094-9-14 | pmc=3283476 | pmid=22260418 |name-list-style=vanc | doi-access=free }}</ref> <ref name=Rheumatoid>{{cite journal | last1=Ajeganova | first1=Sofia | last2=Huizinga | first2=Tom W J | date=November 2014 | title=Rheumatoid arthritis: Seronegative and seropositive RA: alike but different? | journal=Nature Reviews Rheumatology | publisher=Nature Publishing Group | volume=11 | issue=1 | pages=8–9 | doi=10.1038/nrrheum.2014.194 | issn=1759-4804 | pmid=25403158 | s2cid=1405551 |name-list-style=vanc}}</ref> <ref name=Pancreatitis>{{cite journal | last1=Balasubramanian | first1=Gokulakrishnan | last2=Sugumar | first2=Aravind | last3=Smyrk | first3=Thomas C | last4=Takahashi | first4=Naoki | last5=Clain | first5=Jonathan E | last6=Gleeson | first6=Ferga C | last7=Hart | first7=Phil A | last8=Levy | first8=Michael J | last9=Pearson | first9=Randall K | last10=Petersen | first10=Bret T | last11=Topazian | first11=Mark D | last12=Vege | first12=Santhi S | last13=Chari | first13=Suresh T | display-authors=3 | year=2012 | title=Demystifying seronegative autoimmune pancreatitis | url=http://www.pancreatology.net/article/S1424-3903%2812%2900129-9/abstract | journal=Pancreatology | publisher=Elsevier | volume=12 | issue=4 | pages=289–294 | doi=10.1016/j.pan.2012.05.003 | pmid=22898628 |name-list-style=vanc| url-access=subscription }}</ref> <ref name=Novel>{{cite journal | last1=Somers | first1=Klaartje | last2=Geusens | first2=Piet | last3=Elewaut | first3=Dirk | last4=De Keyser | first4=Filip | last5=Rummens | first5=Jean-Luc | last6=Coenen | first6=Marieke | last7=Blom | first7=Marlies | last8=Stinissen | first8=Piet | last9=Veerle | first9=Somers | display-authors=3 | date=February 2011 | title=Novel autoantibody markers for early and seronegative rheumatoid arthritis | journal=Journal of Autoimmunity | publisher=Elsevier | volume=36 | issue=1 | pages=33–46 | doi=10.1016/j.jaut.2010.10.003 | issn=0896-8411 | pmid=21071175 |name-list-style=vanc}}</ref> <ref name=Myasthenia>{{cite journal | last1=Pevzner | first1=Alexandra | last2=Schoser | first2=Benedikt | last3=Peters | first3=Katja | last4=Cosma | first4=Nicoleta-Carmen | last5=Karakatsani | first5=Andromachi | last6=Schalke | first6=Berthold | last7=Melms | first7=Arthur | last8=Kroger | first8=Stephan | display-authors=3 | date=August 2011 | title=Anti-LRP4 autoantibodies in AChR- and MuSK-antibody-negative myasthenia gravis | url=https://www.researchgate.net/publication/51545644 | format=PDF | journal=Journal of Neurology | publisher=Springer-Verlag | volume=259 | issue=3 | pages=427–435 | doi=10.1007/s00415-011-6194-7 | issn=1432-1459 | pmid=21814823 | s2cid=13125248 |name-list-style=vanc}}</ref> </references>

{{HIV and AIDS}}

Category:Serology Category:HIV/AIDS