{{Short description|Chemical compound}} {{Distinguish|α-PCyP}} {{Infobox drug | verifiedrevid = 444089733 | IUPAC_name = 1-(1-phenylcyclohexyl)pyrrolidine | image = Rolicyclidine.svg | image_class = skin-invert-image | width = 125px
<!--Clinical data--> | tradename = | legal_AU = S9 | legal_BR = F2 | legal_BR_comment = <ref>{{Cite web |author=Anvisa |author-link=Brazilian Health Regulatory Agency |date=2023-07-24 |title=RDC Nº 804 - Listas de Substâncias Entorpecentes, Psicotrópicas, Precursoras e Outras sob Controle Especial |trans-title=Collegiate Board Resolution No. 804 - Lists of Narcotic, Psychotropic, Precursor, and Other Substances under Special Control|url=https://www.in.gov.br/en/web/dou/-/resolucao-rdc-n-804-de-24-de-julho-de-2023-498447451 |url-status=live |archive-url=https://web.archive.org/web/20230827163149/https://www.in.gov.br/en/web/dou/-/resolucao-rdc-n-804-de-24-de-julho-de-2023-498447451 |archive-date=2023-08-27 |access-date=2023-08-27 |publisher=Diário Oficial da União |language=pt-BR |publication-date=2023-07-25}}</ref> | legal_CA = Schedule III | legal_UK = Class A | legal_US = Schedule I | legal_DE = Anlage I | legal_UN = P I
<!--Identifiers--> | CAS_number = 2201-39-0 | ATC_prefix = none | PubChem = 62436 | DrugBank_Ref = {{drugbankcite|correct|drugbank}} | DrugBank = DB01549 | ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}} | ChemSpiderID = 56218 | UNII_Ref = {{fdacite|correct|FDA}} | UNII = 183O9O9JE3 | ChEBI_Ref = {{ebicite|correct|EBI}} | ChEBI = 60805 | KEGG_Ref = {{keggcite|correct|kegg}} | KEGG = D12706
<!--Chemical data--> | C=16 | H=23 | N=1 | smiles = c1ccccc1C3(N2CCCC2)CCCCC3 | StdInChI_Ref = {{stdinchicite|correct|chemspider}} | StdInChI = 1S/C16H23N/c1-3-9-15(10-4-1)16(11-5-2-6-12-16)17-13-7-8-14-17/h1,3-4,9-10H,2,5-8,11-14H2 | StdInChIKey_Ref = {{stdinchicite|correct|chemspider}} | StdInChIKey = FYOWWXMGDATDQY-UHFFFAOYSA-N }}
'''Rolicyclidine''' ('''PCPy''') is a dissociative anesthetic that is similar in effects to phencyclidine, but is slightly less potent and has fewer stimulant effects.<ref>{{cite journal | vauthors = Kalir A, Edery H, Pelah Z, Balderman D, Porath G | title = 1-Phenycycloalkylamine derivatives. II. Synthesis and pharmacological activity | journal = Journal of Medicinal Chemistry | volume = 12 | issue = 3 | pages = 473–7 | date = May 1969 | pmid = 4977945 | doi = 10.1021/jm00303a030 }}</ref> It instead produces a sedative effect described as being somewhat similar to a barbiturate, but with additional PCP-like dissociative, anaesthetic and hallucinogenic effects.<ref>DEA Microgram Bulletin, 8, 143, 1975</ref> Due to its similarity in effects to PCP, PCPy was placed into the Schedule I list of illegal drugs in the 1970s, although it has never been widely abused and is now little known.
==See also== * PCP * Arylcyclohexylamine * Picilorex * α-PHP
==References== {{Reflist}}
{{General anesthetics}} {{Dissociatives}} {{Dopamine receptor modulators}} {{Ionotropic glutamate receptor modulators}}
Category:Arylcyclohexylamines Category:Dissociative drugs Category:1-Pyrrolidinyl compounds Category:Designer drugs Category:NMDA receptor antagonists
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