{{Distinguish|Retinitus}} {{Infobox medical condition (new) | name = Retinitis | synonyms = | image = Fundus photograph-CMV retinitis EDA07.JPG | caption = Retinitis caused by CMV (fundus photograph) | pronounce = | field = | symptoms = | complications = | onset = | duration = | types = | causes = | risks = | diagnosis = | differential = | prevention = | treatment = | medication = | prognosis = | frequency = | deaths = }}

'''Retinitis''' is inflammation of the retina in the eye, which can permanently damage the retina and lead to blindness. The retina is the eye's "sensing" tissue. Retinitis may be caused by a number of different infectious agents. Its most common form, called retinitis pigmentosa, has a prevalence of one in every 2,500–7,000 people. This condition is one of the leading causes that leads to blindness in patients in the age range of 20–60 years old.

Retinitis may be caused by several infectious agents, including toxoplasmosis,<ref name="Cecil">{{cite book |last=Goldman |first=Lee |title=Goldman-Cecil Medicine |publisher=Elsevier Saunders |year=2011 |isbn=978-1437727883 |edition=24th |location=Philadelphia |pages=2195}}</ref> cytomegalovirus and candida.<ref name="Kumar">{{cite book |last=Kumar |first=Vinay |title=Robbins basic pathology |publisher=Saunders/Elsevier |year=2007 |isbn=978-1416029731 |edition=8th |location=Philadelphia |chapter=Retina and Vitreous, Other Retinal Degenerations, Retinitis}}</ref> Cytomegalovirus retinitis is an important cause of blindness in AIDS patients.<ref name="Kumar" /> Candida spreading to the retina from the bloodstream usually results in the production of several retinal abscesses.<ref name="Kumar" />

==Symptoms and signs== The first symptom of this disease is usually a slow loss of vision, especially that of night vision, making it harder to drive in the dark. Later signs include loss of peripheral vision, leading to tunnel vision. In some cases, symptoms are experienced in only one of the eyes. Experiencing floaters, flashes, blurred vision and loss of side vision in just one eye may be an early indication of onset of retinitis.{{cn|date=October 2025}} ==Cause== {{Empty section|date=October 2025}}

== Diagnosis == Although there has been extensive research in the past decades on the disease, there is still no evidence-based therapies for this condition which is often diagnosed at an early age, usually in teenagers or young adults.{{cn|date=October 2025}}

To make a specific diagnosis, intraocular fluid samples may be taken and sent for analysis.<ref>{{cite journal |last1=Maghsoudlou |first1=P |last2=Epps |first2=SJ |last3=Guly |first3=CM |last4=Dick |first4=AD |date=28 May 2025 |title=Uveitis in Adults: A Review. |journal=JAMA |doi=10.1001/jama.2025.4358 |pmid=40434762}}</ref> In some cases, blood or cerebrospinal fluid (CSF) are also tested. Imaging may be done to help make the diagnosis.{{cn|date=October 2025}}

==Prevention== Research indicates that some supplements, especially vitamin A, lutein, and omega-3 fatty acids, may slow down the progression of the disease and alleviate symptoms temporarily.{{cn|date=October 2025}}

==Treatment== It is extremely important to see an eye doctor regularly. While supplements mentioned above may help reduce the symptoms, retinitis itself is not curable. Additionally, devices such as low-vision magnifiers can be used to aid vision in patients with despaired vision due to retinitis. Rehabilitation services may also aid the patient so that patients may use their vision in a more effective way. Lastly, it is advisable to wear sunglasses even on gloomy days to protect the eyes from UV radiation.{{cn|date=October 2025}}

== Recent research == Current research on retinitis includes studying stem cells, medications, gene therapies,<ref>{{Cite web |title=Retinitis Pigmentosa Research Advances |url=https://www.fightingblindness.org/research/retinitis-pigmentosa-research-advances-3 |website=Foundation Fighting Blindness |language=en}}</ref> and transplants to help treat/cure this condition. One study including patients with retinitis was conducted by using gene therapy.{{cn|date=October 2025}}

== References == {{reflist}} :* Retinitis. (n.d.). Retrieved December 12, 2017, from https://www.webmd.com/eye-health/retinitis-types-symptoms-treatment#1 :* Parmeggiani, F. (2011). Clinics, Epidemiology and Genetics of Retinitis Pigmentosa. ''Current Genomics'', ''12''(4), 236–237. http://doi.org/10.2174/138920211795860080

== External links == {{Medical resources | DiseasesDB = | ICD10 = {{ICD10|H|30|9|h|30}} | ICD9 = {{ICD9|363.20}} | ICDO = | OMIM = | MedlinePlus = | eMedicineSubj = | eMedicineTopic = | MeshID = D012173 | SNOMED CT = 399463004 }}

{{Eye pathology}} {{Authority control}}

Category:Disorders of choroid and retina