{{Short description|Epithelial cell with excess mitochondria}} [[File:Cytopathology of Warthin's tumor.jpg|thumb|270px|Cytopathology of Warthin's tumor, with typical cellular features (and a relatively uncommon binucleated cell).<ref>Image by Mikael Häggström, MD. References for entries:<br>- {{cite journal| author=Köybaşioğlu FF, Önal B, Han Ü, Adabağ A, Şahpaz A| title=Cytomorphological findings in diagnosis of Warthin tumor | journal=Turk J Med Sci | year= 2020 | volume= 50 | issue= 1 | pages= 148–154 | pmid=31769640 | doi=10.3906/sag-1901-215 | doi-access=free| pmc=7080357 }}<br>Binucleation:<br>- {{cite web|url=http://repository-tnmgrmu.ac.in/464/1/200300307malliga.pdf|title=A correlative cytological and histopathological study on lesions of salivary gland|date=2006-10-18|author=Dr.S. Malliga}}<br>- Chan MKM, McGuire LJ: Cytodiagnosis of Lesions Presenting as Salivary Gland Swellings: A Report of Seven Cases. Diagn Cytopathol 8: 439-443, 1992b.</ref> Pap stain. The relatively large size of the oncocytes is seen when comparing to the lymphocyte.]] [[File:Histopathology of apocrine metaplasia of breast, annotated.png|thumb|290px|Micrograph showing apocrine-type metaplasia of the breast with typical oncocytes.<ref>Image by Mikael Häggström, MD. Reference for findings: {{cite web|url=https://www.pathologyoutlines.com/topic/breastapocrinemetaplasia.html|title=Apocrine metaplasia|author=Carlos C. Diez Freire, M.D., Shahla Masood, M.D.|website=Pathology Outlines}} Last author update: 28 May 2020.</ref> H&E stain.]] [[Image:Renal_oncocytoma2.jpg|right|thumb|'''Oncocytes''' (left of image), as seen in a renal oncocytoma. H&E stain.]] An '''oncocyte''' is an epithelial cell characterized by an excessive number of mitochondria, resulting in an abundant acidophilic, granular cytoplasm. Oncocytes can be benign or malignant.
==Other names== Also known as: *''Hürthle cell'' (thyroid gland only) *''Oxyphilic cell'' *''Askanazy cell'' *''Apocrine-type metaplasia'' (breast gland only). *''Oncocytic cell''
==Etymology== Derived from the Greek root '''onco-''', which means '''mass, bulk'''.
==See also== *Hurthle cell carcinoma, a variant of follicular thyroid carcinoma. *Oncocytoma, a tumour composed of oncocytes, may be found as a less common salivary gland neoplasm also known as oxyphilic adenoma. *Renal oncocytoma, a kidney tumour composed of oncocytes.
==References== {{Reflist}}
==External links== *[http://www.wordinfo.info/words/index/info/view_unit/1474 Wordinfo - words containing onco-, onocho-, -onchus]
Category:Epithelial cells Category:Mitochondria Category:Oncology