Glycolate dehydrogenase

{{infobox enzyme | Name = glycolate dehydrogenase | EC_number = 1.1.99.14 | CAS_number = 37368-32-4 | GO_code = 0019154 | image = | width = | caption = }} In enzymology, '''glycolate dehydrogenase''' ({{EC number|1.1.99.14}}) is an enzyme that catalyzes the chemical reaction

{{chemrxn|width=50%| {{chemrxn/cpd|glycolic acid }} {{chemrxn/txt|+ electron<br>acceptor}} {{chemrxn/arw|direction=reversible }} {{chemrxn/cpd|glyoxylic acid }} {{chemrxn/txt|+ reduced<br>acceptor}} }}

The two substrates of this enzyme are glycolic acid and an electron acceptor. Its products are glyoxylic acid and the corresponding reduced acceptor.<ref>{{KEGG enzyme|1.1.99.14}}</ref><ref>{{cite journal | vauthors = Lord JM | title = Glycolate oxidoreductase in Escherichia coli | journal = Biochimica et Biophysica Acta (BBA) - Bioenergetics | volume = 267 | issue = 2 | pages = 227–37 | date = May 1972 | pmid = 4557653 | doi = 10.1016/0005-2728(72)90111-9 }}</ref>

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with other acceptors. The systematic name of this enzyme class is '''glycolate:acceptor 2-oxidoreductase'''. Other names in common use include '''glycolate oxidoreductase''', '''glycolic acid dehydrogenase''', and '''glycolate:(acceptor) 2-oxidoreductase'''. This enzyme participates in glyoxylate and dicarboxylate metabolism.

== References == {{reflist}}

Category:EC 1.1.99 Category:Enzymes of unknown structure