{{Short description|Additive to improve flow of a powder}} {{refimprove|date=September 2014}} A '''glidant''' is a substance that is added to a powder to improve its flowability. A glidant will only work at a certain range of concentrations. Above a certain concentration, the glidant will in fact function to inhibit flowability.
In tablet manufacture, glidants are usually added just prior to compression.
==Examples== Examples of glidants include ascorbyl palmitate,<ref>{{Cite patent|title=Use of ascorbyl palmitate and ascorbyl stearate as glidant for tablets|country=KR|number=101440100|pubdate=2014-09-17|assign1=Cosmax Bio Co. Ltd.|inventor1-last=Kim|inventor1-first=Dong Sup|inventor2-last=Baik|inventor2-first=Joo Hyun|inventor3-last=Jung|inventor3-first=Hyun Mook|inventor4=Lee, Jae Hyun;Lee, Kyung Jin}}</ref> calcium palmitate,<ref>{{Cite web|title=Vitamin & Supplement Recommendations for Your Health Concerns - Swanson®|url=https://www.swansonvitamins.com/quality/additives-fillers.html|access-date=2021-02-05|website=www.swansonvitamins.com|archive-date=2021-02-28|archive-url=https://web.archive.org/web/20210228165511/https://www.swansonvitamins.com/quality/additives-fillers.html|url-status=live}}</ref> magnesium stearate, fumed silica (colloidal silicon dioxide), starch and talc.<ref name=SMI>{{cite web|title=SMI: Talc as a Glidant & Lubricant|url=http://www.specialtyminerals.com/specialty-applications/specialty-markets-for-minerals/nutritional-supplements/talc-as-a-glidant-lubricant/|publisher=2012 Specialty Minerals Inc.|accessdate=19 March 2014|archive-date=28 August 2008|archive-url=https://web.archive.org/web/20080828023520/http://www.specialtyminerals.com/specialty-applications/specialty-markets-for-minerals/nutritional-supplements/talc-as-a-glidant-lubricant/|url-status=live}}</ref>
==Mechanism of action== A glidant's effect is due to the counter-action of factors that cause poor flowability of powders. For instance, correcting surface irregularity, reducing interparticular friction and decreasing surface charge. The result is a decrease in the angle of repose which is an indication of an enhanced powder's flowability.
==References== {{reflist}}
Category:Chemical engineering Category:Drug manufacturing Category:Granularity of materials Category:Powders
{{material-stub}}