{{Short description | Iron oxidizing enzyme, Fe(II) to Fe(III) conversion}} {{infobox enzyme | Name = Ferroxidase | EC_number = 1.16.3.1 | CAS_number = 9031-37-2 | GO_code = 0004323 | image = | width = | caption = }} '''Ferroxidase''' also known as '''Fe(II):oxygen oxidoreductase''' is an enzyme that catalyzes the oxidization of iron II to iron III: : 4 Fe<sup>2+</sup> + 4 H<sup>+</sup> + O<sub>2</sub> ⇔ 4 Fe<sup>3+</sup> + 2H<sub>2</sub>O
== Examples ==
Human genes encoding proteins with ferroxidase activity include: * CP – Ceruloplasmin * FTH1 – Ferritin heavy chain * FTMT – Ferritin, mitochondrial * HEPH - Hephaestin
== References == {{refbegin}} * {{cite journal |vauthors=Cox JC, Boxer DH | title = The role of rusticyanin, a blue copper protein, in the electron transport chain of Thiobacillus ferrooxidans grown on iron or thiosulfate | journal=Biotechnol. Appl. Biochem. | year = 1986 | volume = 8 | pages = 269–275}} * {{cite journal | author = Osaki S | title = Kinetic studies of ferrous ion oxidation with crystalline human ferroxidase (ceruloplasmin) | journal = J. Biol. Chem. | volume = 241 | issue = 21 | pages = 5053–9 |date=November 1966 | doi = 10.1016/S0021-9258(18)99669-9 | pmid = 5925868 | doi-access = free }} * {{cite journal |vauthors=Osaki S, Walaas O | title = Kinetic studies of ferrous ion oxidation with crystalline human ferroxidase. II. Rate constants at various steps and formation of a possible enzyme-substrate complex | journal = J. Biol. Chem. | volume = 242 | issue = 11 | pages = 2653–7 |date=June 1967 | doi = 10.1016/S0021-9258(18)99620-1 | pmid = 6027241 | doi-access = free }} {{refend}}
{{Other oxidoreductases}} {{Enzymes}} {{Portal bar|Biology|border=no}}
Category:EC 1.16.3
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