{{Chembox <!-- Images --> | ImageFile = Erucamide.svg | ImageSize = 250px <!-- Names --> | IUPACName = (''Z'')-Docos-13-enamide | OtherNames = {{unbulletedlist|Erucylamide|Erucic acid amide|Erucic amide|''cis''-13-Docosenamide}} <!-- Sections --> | Section1 = {{Chembox Identifiers | CASNo = 112-84-5 | ChEBI = 142245 | ChEMBL = 1232565 | ChemSpiderID = 4517399 | EC_number = 204-009-2 | PubChem = 5365371 | UNII = 0V89VY25BN | SMILES = CCCCCCCC/C=C\CCCCCCCCCCCC(=O)N | InChI = 1S/C22H43NO/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-22(23)24/h9-10H,2-8,11-21H2,1H3,(H2,23,24)/b10-9- | InChIKey = UAUDZVJPLUQNMU-KTKRTIGZSA-N }} | Section2 = {{Chembox Properties | C = 22 | H = 43 | N = 1 | O = 1 | Appearance = White solid<ref name=GESTIS>{{GESTIS|ZVG=30990}}</ref> | Density = | MeltingPtC = 83.5-84 | MeltingPt_ref = <ref name=GESTIS/> | BoilingPt = | Solubility = Insoluble<ref name=GESTIS/> }} | Section3 = {{Chembox Hazards | MainHazards = | FlashPt = | AutoignitionPt = }} }}
'''Erucamide''' is a fatty acid amide resulting from the formal condensation of erucic acid with ammonia. It has a role as a metabolite in humans and other animals and in plants.<ref name=PubChem>{{PubChem|5365371}}</ref> In the plastic manufacturing industry, it is commonly used as a slip additive.<ref name=PubChem/><ref>{{cite web | url = https://www.ebi.ac.uk/chebi/CHEBI:142245 | title = CHEBI:142245 - erucamide | work = ChEBI }}</ref>
==Uses== Erucamide is used as a slip promoter, antiblock agent, and lubricant in plastics.<ref>{{cite web | url = https://www.lepuz.cn/product/erucamide | title = Erucamide | publisher = Lepuz }}</ref> It serves as a viscosity controlling and opacifying agent in cosmetics.<ref>{{cite web | url = https://www.deascal.com/ingredient-information/erucamide | title = Erucamide: An In-Depth Look at Its Role in Cosmetics | date = October 15, 2024 | publisher = Deascal }}</ref> In industry, it functions as a processing aid, lubricating agent, anti-adhesive agent, and corrosion inhibitor. In the United States, it is authorized as an indirect food additive in adhesives under 21 CFR 175.105.<ref>{{CodeFedReg |21|175|105}}</ref>
==Research== Erucamide has been reported to ameliorate depression and anxiety-like behaviors in mouse models.<ref>{{cite journal | journal = Neuroscience Letters | volume = 640 | date = 2017 | pages = 6-12 | title = Antidepressant and anxiolytic-like behavioral effects of erucamide, a bioactive fatty acid amide, involving the hypothalamus–pituitary–adrenal axis in mice | author = Miao-Miao Li, Zheng-er Jiang, Ling-Yun Song, Zhe-Shan Quan, Hai-Ling Yu | doi = 10.1016/j.neulet.2016.12.072 }}</ref>
==References== {{reflist}}
Category:Fatty acid amides