{{Chembox | ImageFile = Daphnoretin.svg | ImageSize = 250px | ImageAlt = | PIN = 7-Hydroxy-6-methoxy-3-[(2-oxo-2''H''-1-benzopyran-7-yl)oxy]-2''H''-1-benzopyran-2-one | OtherNames = Thymelol |Section1={{Chembox Identifiers | CASNo = 2034-69-7 | CASNo_Ref = {{cascite|correct|CAS}} | UNII_Ref = {{fdacite|correct|FDA}} | UNII = 1A7Q3KY3LH | PubChem = 5281406 | ChemSpiderID = 4444756 | SMILES = COC1=C(C=C2C(=C1)C=C(C(=O)O2)OC3=CC4=C(C=C3)C=CC(=O)O4)O | InChI = 1/C19H12O7/c1-23-16-6-11-7-17(19(22)26-15(11)9-13(16)20)24-12-4-2-10-3-5-18(21)25-14(10)8-12/h2-9,20H,1H3 | InChIKey = JRHMMVBOTXEHGJ-UHFFFAOYAG | StdInChI = 1S/C19H12O7/c1-23-16-6-11-7-17(19(22)26-15(11)9-13(16)20)24-12-4-2-10-3-5-18(21)25-14(10)8-12/h2-9,20H,1H3 | StdInChIKey = JRHMMVBOTXEHGJ-UHFFFAOYSA-N}} |Section2={{Chembox Properties | C=19 | H=12 | O=7 | Appearance = | Density = | MeltingPt = | BoilingPt = | Solubility = }} |Section3={{Chembox Hazards | MainHazards = | FlashPt = | AutoignitionPt = }} }}
'''Daphnoretin''' is a protein kinase C activator isolated from ''Wikstroemia indica'' C.A. Mey, one of the 50 fundamental herbs in traditional Chinese medicine.<ref>{{cite journal | last1 =Gu | first1 =Shoubin | last2 =He | first2 =Jinhai | title =Daphnoretin induces cell cycle arrest and apoptosis in human osteosarcoma (HOS) cells | journal =Molecules | volume =17 | issue =1 | pages =598–612 | publisher = MDPI | date =January 9, 2012 | doi =10.3390/molecules17010598 | pmid=22231496| pmc =6268824 | doi-access =free }}</ref><ref>{{cite journal | last1 =Ko | first1 =Feng N. | last2 =Chang | first2 =Ya L. | last3 =Kuo | first3 =Yueh H. | last4 =Lin | first4 =Yun L. | last5 =Teng | first5 = Che M. | title =Daphnoretin, a new protein kinase C activator isolated from Wikstroemia indica C.A. Mey. | journal =Biochemical Journal | volume =295 | issue =1 | pages =321–327 | publisher =Portland Press Limited | date =October 1, 1993 | pmc=1134857 | pmid=8216237 | doi=10.1042/bj2950321}}</ref> It has also been found to occur in ''Stellera chamaejasme'' - the single species in a genus closely related to ''Wikstroemia'' within the family Thymelaceae.<ref name= "Medicinal Mongolia">''Medicinal Plants in Mongolia'' pub. World Health Organization, Regional Office for the Western Pacific Region 2013 {{ISBN|978 92 9061 632 0}} [https://web.archive.org/web/20180428182720/http://www.wpro.who.int/publications/Medicinal_Plants_in_Mongolia_VF.pdf]</ref>
==References== {{Reflist}}
Category:Wikstroemia Category:Coumarins Category:Protein kinase C activators Category:Resorcinol ethers
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