{{Infobox medical intervention | name = Chemoradiotherapy | synonym = | image = | caption = | alt = | pronounce = | specialty = oncology | synonyms = | ICD10 = | ICD9 = | ICD9unlinked = | CPT = | MeshID = | LOINC = | other_codes = | MedlinePlus = | eMedicine = }} '''Chemoradiotherapy''' ('''CRT''', '''CRTx''', '''CT-RT''') is the combination of chemotherapy and radiotherapy to treat cancer.<ref>{{Cite web |url=http://www.medterms.com/script/main/art.asp?articlekey=39967 |title=Medical Definition of Chemoradiotherapy |access-date=2010-02-09 |archive-date=2012-08-09 |archive-url=https://web.archive.org/web/20120809162405/http://www.medterms.com/script/main/art.asp?articlekey=39967 |url-status=dead }}</ref> Synonyms include '''radiochemotherapy''' ('''RCT''', '''RCTx''', '''RT-CT''') and '''chemoradiation'''. It is a type of multimodal cancer therapy.
Chemoradiation can be ''concurrent'' <ref name=Neuner2009/> (together) or ''sequential'' (one after the other).<ref>[http://www.medpagetoday.com/MeetingCoverage/MGICS/62668 Older Patients with GI Cancers Don't Always Receive Tx]</ref>
The chemotherapy component can be or include a radiosensitizing agent.<ref name=Neuner2009>{{cite journal| pmc=2684724 | pmid=19461907 | volume=3 | issue=2 | title=Chemoradiotherapy for esophageal cancer |vauthors=Neuner G, Patel A, Suntharalingam M| journal=Gastrointest Cancer Res | pages=57–65| year=2009 }}</ref>
Chemoradiotherapy as neoadjuvant therapy before surgery has been shown to be effective in esophageal cancer.<ref>{{Cite web|url=https://www.cancer.gov/types/esophageal/research/preop-treatment-improves-survival|title=Preoperative Chemotherapy, Radiation Improve Survival in Esophageal Cancer (Updated)|date=2012-06-14|website=National Cancer Institute|language=en|access-date=2019-05-06}}</ref>
== References == {{reflist}}
==Further reading== * {{cite journal |last1=Eifel |first1=Patricia J. |title=Chemoradiotherapy in the treatment of cervical cancer |journal=Seminars in Radiation Oncology |volume=16 |issue=3 |pages=177–185 |doi=10.1016/j.semradonc.2006.02.007 |pmid=16814159 |issn=1053-4296|year=2006 }}
==External links== * [http://www.nhs.uk/ipgmedia/national/Macmillan%20Cancer%20Support/Assets/ChemotherapyandchemoradiotherapyforrectalcancerMCS11pages.pdf Chemotherapy and chemoradiotherapy for rectal cancer. (Macmillan/NHS)] {{Medicine}} Category:Radiation therapy
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