Aceturic acid

{{Chembox | ImageFile = N-acetylglycine Structural Formula V.1.svg | ImageClass = skin-invert-image | ImageSize = | ImageAlt = | PIN = Acetamidoacetic acid <!-- Rule P-14.3.4.6 All locants are omitted for parent compounds when all substitutable hydrogen atoms have the same locant. --> | OtherNames = Acetylglycine<br />''N''-Acetylglycine<br />2-Acetamidoacetic acid<br />Acetylglycocoll |Section1={{Chembox Identifiers | Abbreviations = AcGly | CASNo = 543-24-8 | CASNo_Ref = {{cascite|correct|CAS}} | UNII = U2UT4677KR | UNII_Ref = {{fdacite|correct|FDA}} | PubChem = 10972 | ChemSpiderID = 10507 | EC_number = 208-839-6 | ChEMBL = 289004 | DrugBank = DB02713 | SMILES = CC(=O)NCC(=O)O | StdInChI =1S/C4H7NO3/c1-3(6)5-2-4(7)8/h2H2,1H3,(H,5,6)(H,7,8) | StdInChIKey = OKJIRPAQVSHGFK-UHFFFAOYSA-N }} |Section2={{Chembox Properties | C=4 | H=7 | N=1 | O=3 | MolarMass = | Appearance = White powder or needles | Density = | MeltingPtC = 206 to 208 | MeltingPt_notes = | BoilingPt = | pKa = 3.67 (H₂O)<ref name="CRC97">{{cite book | editor= Haynes, William M. | year = 2016 | title = CRC Handbook of Chemistry and Physics | edition = 97th | publisher = CRC Press | isbn = 978-1498754286 | page=5–88 | title-link = CRC Handbook of Chemistry and Physics }}</ref> | Solubility = 2.7% at 15 °C}} |Section3={{Chembox Hazards | MainHazards = | FlashPt = | AutoignitionPt = }} |Section4={{Chembox Related | OtherCompounds = ''N''-Acetylglycinamide }} }}

'''Aceturic acid''' ('''''N''-acetylglycine''') is a derivative of the amino acid glycine. The conjugate base of this carboxylic acid is called ''aceturate'', a term used for its esters and salts.

==Preparation== Aceturic acid can be prepared by warming glycine either with a slight excess of acetic anhydride in benzene,<ref>{{cite journal|title = Hydrazide und Azide organischer Säuren. X Abhandlung. 35. Ueber Hydrazide substituirter Amidosäuren und das Hydrazid der Fumarsäure|first1 = Th.|last1 = Curtius|authorlink1 = Theodor Curtius|first2 = R.|last2 = Radenhausen|journal = J. Prakt. Chem.|volume = 52|issue = 1|pages = 433–454|year = 1895|doi = 10.1002/prac.18950520134|url = https://zenodo.org/record/1427988}}</ref> or with an equal molar amount of acetic anhydride in glacial (concentrated) acetic acid.<ref>{{cite journal|title = The Condensation of Aromatic Aldehydes with Glycine and Acetylglycine|last = Dakin|first = H. D.|journal = J. Biol. Chem.|volume = 82|issue = 2|pages = 439–446|year = 1929|doi = 10.1016/S0021-9258(20)78291-8|url = http://www.jbc.org/content/82/2/439.full.pdf|doi-access = free}}</ref>

==See also== * Aceglutamide (α-''N''-Acetylglutamine) * ''N''-Acetylaspartic acid * ''N''-Acetylcysteine * ''N''-Acetylglutamic acid * ''N''-Acetylleucine * ''N''^ε-Acetyllysine * ''N''-Acetyltyrosine * Aceburic acid

==References== {{Reflist}}

Category:Acetamides

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