'''Zippelius''' is a surname. Notable people with the surname include:

*Alexander Zippelius (1797–1828), Dutch horticulturalist and botanical collector *Annette Zippelius (born 1949), German physicist *Nicolas Zippelius (born 1987), German politician, member of the German Bundestag (MdP) *Reinhold Zippelius (born 1928), German jurist

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