{{short description|Protein-coding gene in humans}} {{Infobox_gene}} '''Zinc finger homeobox protein 3''' is a protein that in humans is encoded by the ''ZFHX3'' gene.<ref name="pmid1719379">{{cite journal | vauthors = Morinaga T, Yasuda H, Hashimoto T, Higashio K, Tamaoki T | title = A human alpha-fetoprotein enhancer-binding protein, ATBF1, contains four homeodomains and seventeen zinc fingers | journal = Mol Cell Biol | volume = 11 | issue = 12 | pages = 6041–9 |date=Dec 1991 | pmid = 1719379 | pmc = 361769 | doi = 10.1128/MCB.11.12.6041}}</ref><ref name="pmid7592926">{{cite journal | vauthors = Miura Y, Tam T, Ido A, Morinaga T, Miki T, Hashimoto T, Tamaoki T | title = Cloning and characterization of an ATBF1 isoform that expresses in a neuronal differentiation-dependent manner | journal = J Biol Chem | volume = 270 | issue = 45 | pages = 26840–8 |date=Dec 1995 | pmid = 7592926 | doi =10.1074/jbc.270.45.26840 | doi-access = free }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: ATBF1 AT-binding transcription factor 1| url = https://www.ncbi.nlm.nih.gov/gene?Db=gene&Cmd=ShowDetailView&TermToSearch=463}}</ref>
==References== {{reflist}}
==Further reading== {{refbegin | 2}} *{{cite journal | vauthors=Yamada K, Miura Y, Scheidl T |title=Assignment of the human ATBF1 transcription factor gene to chromosome 16q22.3-q23.1 |journal=Genomics |volume=29 |issue= 2 |pages= 552–3 |year= 1996 |pmid= 8666409 |doi= 10.1006/geno.1995.9967 |display-authors=etal}} *{{cite journal | vauthors=Bedford MT, Chan DC, Leder P |title=FBP WW domains and the Abl SH3 domain bind to a specific class of proline-rich ligands |journal=EMBO J. |volume=16 |issue= 9 |pages= 2376–83 |year= 1997 |pmid= 9171351 |doi= 10.1093/emboj/16.9.2376 | pmc=1169838 }} *{{cite journal | vauthors=Kaspar P, Dvoráková M, Králová J |title=Myb-interacting protein, ATBF1, represses transcriptional activity of Myb oncoprotein |journal=J. Biol. Chem. |volume=274 |issue= 20 |pages= 14422–8 |year= 1999 |pmid= 10318867 |doi=10.1074/jbc.274.20.14422 |display-authors=etal|doi-access=free }} *{{cite journal | vauthors=Loftus BJ, Kim UJ, Sneddon VP |title=Genome duplications and other features in 12 Mb of DNA sequence from human chromosome 16p and 16q |journal=Genomics |volume=60 |issue= 3 |pages= 295–308 |year= 1999 |pmid= 10493829 |doi= 10.1006/geno.1999.5927 |display-authors=etal}} *{{cite journal | vauthors=Kaushik N, Malaspina A, de Belleroche J |title=Characterization of trinucleotide- and tandem repeat-containing transcripts obtained from human spinal cord cDNA library by high-density filter hybridization |journal=DNA Cell Biol. |volume=19 |issue= 5 |pages= 265–73 |year= 2000 |pmid= 10855793 |doi= 10.1089/10445490050021177 }} *{{cite journal | vauthors=Strausberg RL, Feingold EA, Grouse LH |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 |bibcode=2002PNAS...9916899M |display-authors=etal|doi-access=free }} *{{cite journal | vauthors=Iida M, Imura J, Furuichi T |title=Alteration of the AT motif binding factor-1 expression in alpha-fetoprotein producing gastric cancer: is it an event for differentiation and proliferation of the tumors? |journal=Oncol. Rep. |volume=11 |issue= 1 |pages= 3–7 |year= 2004 |pmid= 14654895 |doi= 10.3892/or.11.1.3|display-authors=etal}} *{{cite journal | vauthors=Nojiri S, Joh T, Miura Y |title=ATBF1 enhances the suppression of STAT3 signaling by interaction with PIAS3 |journal=Biochem. Biophys. Res. Commun. |volume=314 |issue= 1 |pages= 97–103 |year= 2004 |pmid= 14715251 |doi=10.1016/j.bbrc.2003.12.054 |display-authors=etal}} *{{cite journal | vauthors=Martin J, Han C, Gordon LA |title=The sequence and analysis of duplication-rich human chromosome 16 |journal=Nature |volume=432 |issue= 7020 |pages= 988–94 |year= 2005 |pmid= 15616553 |doi= 10.1038/nature03187 |bibcode=2004Natur.432..988M |display-authors=etal|doi-access=free }} *{{cite journal | vauthors=Zhang Z, Yamashita H, Toyama T |title=ATBF1-a messenger RNA expression is correlated with better prognosis in breast cancer |journal=Clin. Cancer Res. |volume=11 |issue= 1 |pages= 193–8 |year= 2005 |doi=10.1158/1078-0432.193.11.1 |pmid= 15671546 |display-authors=etal|doi-access=free }} *{{cite journal | vauthors=Sun X, Frierson HF, Chen C |title=Frequent somatic mutations of the transcription factor ATBF1 in human prostate cancer |journal=Nat. Genet. |volume=37 |issue= 4 |pages= 407–12 |year= 2005 |pmid= 15750593 |doi= 10.1038/ng1528 |s2cid=19458711 |display-authors=etal}} *{{cite journal | vauthors=Rual JF, Venkatesan K, Hao T |title=Towards a proteome-scale map of the human protein-protein interaction network |journal=Nature |volume=437 |issue= 7062 |pages= 1173–8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209 |bibcode=2005Natur.437.1173R |s2cid=4427026 |display-authors=etal}} *{{cite journal | vauthors=Xu J, Sauvageot J, Ewing CM |title=Germline ATBF1 mutations and prostate cancer risk |journal=Prostate |volume=66 |issue= 10 |pages= 1082–5 |year= 2006 |pmid= 16637072 |doi= 10.1002/pros.20430 |s2cid=21238472 |display-authors=etal|doi-access=free }} *{{cite journal | vauthors=Sun X, Zhou Y, Otto KB |title=Infrequent mutation of ATBF1 in human breast cancer |journal=J. Cancer Res. Clin. Oncol. |volume=133 |issue= 2 |pages= 103–5 |year= 2007 |pmid= 16932943 |doi= 10.1007/s00432-006-0148-y |s2cid=12378418 |display-authors=etal|pmc=12160847 }} *{{cite journal | vauthors=Olsen JV, Blagoev B, Gnad F |title=Global, in vivo, and site-specific phosphorylation dynamics in signaling networks |journal=Cell |volume=127 |issue= 3 |pages= 635–48 |year= 2006 |pmid= 17081983 |doi= 10.1016/j.cell.2006.09.026 |s2cid=7827573 |display-authors=etal|doi-access=free }} *{{cite journal | vauthors=Mori Y, Kataoka H, Miura Y |title=Subcellular localization of ATBF1 regulates MUC5AC transcription in gastric cancer |journal=Int. J. Cancer |volume=121 |issue= 2 |pages= 241–7 |year= 2007 |pmid= 17330845 |doi= 10.1002/ijc.22654 |s2cid=37176312 |display-authors=etal|doi-access=free }} *{{cite journal | vauthors=Cho YG, Song JH, Kim CJ |title=Genetic alterations of the ATBF1 gene in gastric cancer |journal=Clin. Cancer Res. |volume=13 |issue= 15 Pt 1 |pages= 4355–9 |year= 2007 |pmid= 17671116 |doi= 10.1158/1078-0432.CCR-07-0619 |display-authors=etal|doi-access=free }} {{refend}}
== External links == * {{MeshName|ATBF1+protein,+human}} * {{UCSC gene info|ZFHX3}}
{{PDB Gallery|geneid=463}} {{Transcription factors|g2}}
Category:Transcription factors
{{gene-16-stub}}