'''Vespignani''' is an Italian surname. Notable people with the surname include:

*Alessandro Vespignani (born 1965), Italian physicist *Renzo Vespignani (1924–2001), Italian painter, printmaker and illustrator *Virginio Vespignani (1808–1882), Italian architect *Netta Vespignani, a painter and the father of Veronica Gentili

{{surname|Vespignani}}

Category:Italian-language surnames