VSIG1

{{Short description|Protein-coding gene in the species Homo sapiens}} {{Infobox_gene}}

'''V-set and immunoglobulin domain containing 1''' is a protein that in humans is encoded by the VSIG1 gene.<ref name="entrez"> {{cite web | title = Entrez Gene: V-set and immunoglobulin domain containing 1 | url = https://www.ncbi.nlm.nih.gov/gene/340547 | access-date = 2018-09-09 }}</ref>

==Function== This gene encodes a member of the junctional adhesion molecule (JAM) family. The encoded protein contains multiple glycosylation sites at the N-terminal region, and multiple phosphorylation sites and glutamic acid/proline (EP) repeats at the C-terminal region. The gene is expressed in a normal stomach and testis, as well as in gastric, esophageal, and ovarian cancers. Alternatively spliced transcript variants, encoding different isoforms, have been found for this gene. [provided by RefSeq, Dec 2009].

== References == {{reflist}}

== Further reading == {{refbegin | 2}} *{{cite journal |vauthors=Scanlan MJ, Ritter G, Yin BW, Williams C, Cohen LS, Coplan KA, Fortunato SR, Frosina D, Lee SY, Murray AE, Chua R, Filonenko VV, Sato E, Old LJ, Jungbluth AA |title=Glycoprotein A34, a novel target for antibody-based cancer immunotherapy |journal=Cancer Immun. |volume=6 |pages=2 |date=January 2006 |pmid=16405301 }} *{{cite journal |vauthors=Chen Y, Pan K, Li S, Xia J, Wang W, Chen J, Zhao J, Lü L, Wang D, Pan Q, Wang Q, Li Y, He J, Li Q |title=Decreased expression of V-set and immunoglobulin domain containing 1 (VSIG1) is associated with poor prognosis in primary gastric cancer |journal=J Surg Oncol |volume=106 |issue=3 |pages=286–93 |date=September 2012 |pmid=22095633 |doi=10.1002/jso.22150 |url=https://deepblue.lib.umich.edu/bitstream/2027.42/92382/1/22150_ftp.pdf|hdl=2027.42/92382 |s2cid=12675519 |hdl-access=free }}