Terry Speed

{{Short description|Australian statistician at the Walter and Eliza Hall Institute of Medical Research}} {{Use dmy dates|date=October 2016}} {{Use Australian English|date=October 2016}} {{Infobox scientist | name = Terry Speed | image = Terry Speed 1.jpg | birth_name = Terence Paul Speed | birth_date = {{Birth date and age|df=yes|1943|3|14}}<ref name=whoswho>{{Who's Who | title=SPEED, Prof. Terence Paul | id = U258569 | volume = 2015 | edition = online [[Oxford University Press]]}}</ref> | citizenship = [[Australia]] | alma_mater = [[Monash University]] (PhD) | doctoral_students = {{plainlist|1= *[[Jim Pitman]] *[[Sandrine Dudoit]] *[[Jean Yang]] *[[Bin Yu]] }} | fields = {{Plainlist| * [[Statistics]] * [[Bioinformatics]]}} | workplaces = {{Plainlist| * [[Walter and Eliza Hall Institute of Medical Research]] * [[University of California, Berkeley]] * [[University of Sheffield]]<ref name=whoswho/>}} | thesis_title = Some topics in the theory of distributive lattices | thesis_year = 1968 | thesis_url = https://books.google.com/books?id=kSgKNQAACAAJ | doctoral_advisor = Peter D. Finch<ref name=mathgene>{{MathGenealogy |id=30979}}</ref> | spouse = {{marriage|Freda Elizabeth (Sally) Pollard|1964}}<ref name=whoswho/> | awards = {{Plainlist| * [[Fellow of the Royal Society|FRS]] (2013) * [[Prime Minister's Prizes for Science]] (2013)}} | website ={{Plainlist| * {{URL|http://www.wehi.edu.au/people/terry-speed}}}} }} {{Scholia|author}} '''Terence Paul "Terry" Speed''' (born 14 March 1943 in [[Victor Harbor, South Australia|Victor Harbor]], [[South Australia]]),<ref name=whoswho/> [[Fellow of the Australian Academy of Science|FAA]] [[Fellow of the Royal Society|FRS]]<ref name=royal>{{cite web |url=https://royalsociety.org/people/fellowship/2013/terence-speed |title = Professor Terry Speed FRS|publisher=The Royal Society |archive-date=2015-02-03 |archive-url=https://web.archive.org/web/20150203211701/https://royalsociety.org/people/fellowship/2013/terence-speed/ |location=London}}</ref> is an Australian [[Statistics|statistician]]. A senior principal research scientist at the [[Walter and Eliza Hall Institute of Medical Research]], he is known for his contributions to the [[analysis of variance]] and [[bioinformatics]], and in particular to the analysis of [[microarray]] data.

==Early life and education== Terry Speed was born in [[Victor Harbor, South Australia|Victor Harbor]], in [[South Australia]], and grew up in [[Melbourne]]. In 1961, he started a joint degree in medicine and science at the [[University of Melbourne]], but later focussed on science only, obtaining a honours degree in mathematics and statistics in 1964.

Speed obtained a [[Ph.D.]] from [[Monash University]] in 1968 with a thesis titled ''Some topics in the theory of distributive lattices'' under the supervision of Peter D. Finch.<ref name=mathgene/><ref>{{Cite book | editor1-last = Dudoit | editor1-first = Sandrine | editor1-link = Sandrine Dudoit | doi = 10.1007/978-1-4614-1347-9 | title = Selected Works of Terry Speed | year = 2012 | isbn = 978-1-4614-1346-2 }}</ref>

==Career== After his PhD, Terry Speed took a lecturing position in [[Sheffield]] ([[United Kingdom]]), at the [[Manchester-Sheffield School of Probability and Statistics]]. In 1974, he returned to Australia, becoming assistant professor at the [[University of Western Australia]], heading the statisticians in the department of mathematics. He then became professor in 1975 and head of department in 1982. In 1984, Terry Speed became chief of the division of mathematics and statistics at [[CSIRO]], the Commonwealth Scientific and Industrial Research Organisation.

After a two-month visit in the department of statistics at the [[University of California, Berkeley]] in 1984, he applied for a permanent position and became a tenured professor there in 1987. In 1996, [[Suzanne Cory]], director of the [[Walter and Eliza Hall Institute of Medical Research]] (WEHI), in [[Melbourne]] and former high-school classmate of Speed, invited him to start a [[bioinformatics]] group at the institute. Starting in 1997, he shared his time between the two institutions.

In 2009, he retired from the [[University of California, Berkeley]], while keeping academic collaborations with the university, including the supervision of PhD students and postdocs. He started working full time at WEHI, where he was head of the Bioinformatics division until 31 August 2014, and has remained a laboratory head since then. He also served on the Mathematical Sciences jury for the [[Infosys Prize]] in 2009 and 2010.

In 2016, a former colleague and a former post-doctoral researcher from the University of California, Berkeley, filed a complaint of sexual harassment against Speed, with the allegedly infringing behavior occurring in 2002.<ref>[http://www.abc.net.au/news/2018-03-23/terry-speed-ally-of-women-in-science-accused-of-harassment/9546170 'Ally of women in science' Professor Terry Speed accused of harassment], [[Australian Broadcasting Corporation]], published on 23 March 2018, retrieved on 23 March 2018</ref><ref>[https://web.archive.org/web/20180123024827/https://www.wehi.edu.au/statement Statement] by [[WEHI]], on 22 January 2018, retrieved on 23 March 2018</ref>

Speed has supervised at least 72 research students.<ref name=mathgene/>

== Notable work ==

Terry Speed has contributed to a wide range of subjects,<ref name=oshlack>{{Cite journal | last1 = Gilad | first1 = Y. | last2 = Oshlack | first2 = A. | author-link2 = Alicia Oshlack | last3 = Smyth | first3 = G. K. | last4 = Speed | first4 = T. P. | author-link4 = Terry Speed | last5 = White | first5 = K. P. | title = Expression profiling in primates reveals a rapid evolution of human transcription factors | doi = 10.1038/nature04559 | journal = Nature | volume = 440 | issue = 7081 | pages = 242–245 | year = 2006 | pmid = 16525476 | bibcode = 2006Natur.440..242G | doi-access = free }}</ref><ref>{{Cite journal | pmid = 14597310 | year = 2003 | last1 = Smyth | first1 = G. K. | title = Normalization of cDNA microarray data | journal = Methods | volume = 31 | issue = 4 | pages = 265–73 | last2 = Speed | first2 = T | doi=10.1016/s1046-2023(03)00155-5 | citeseerx = 10.1.1.322.98 }}</ref><ref>{{Cite journal | pmid = 17157791 | pmc = 2730521 | year = 2006 | last1 = Neve | first1 = R. M. | title = A collection of breast cancer cell lines for the study of functionally distinct cancer subtypes | journal = Cancer Cell | volume = 10 | issue = 6 | pages = 515–27 | last2 = Chin | first2 = K | last3 = Fridlyand | first3 = J | last4 = Yeh | first4 = J | last5 = Baehner | first5 = F. L. | last6 = Fevr | first6 = T | last7 = Clark | first7 = L | last8 = Bayani | first8 = N | last9 = Coppe | first9 = J. P. | last10 = Tong | first10 = F | last11 = Speed | first11 = T | last12 = Spellman | first12 = P. T. | last13 = Devries | first13 = S | last14 = Lapuk | first14 = A | last15 = Wang | first15 = N. J. | last16 = Kuo | first16 = W. L. | last17 = Stilwell | first17 = J. L. | last18 = Pinkel | first18 = D | last19 = Albertson | first19 = D. G. | last20 = Waldman | first20 = F. M. | last21 = McCormick | first21 = F | last22 = Dickson | first22 = R. B. | last23 = Johnson | first23 = M. D. | last24 = Lippman | first24 = M | last25 = Ethier | first25 = S | last26 = Gazdar | first26 = A | last27 = Gray | first27 = J. W. | doi = 10.1016/j.ccr.2006.10.008 }}</ref> including [[distributive lattice]]s, [[ring theory]], [[analysis of variance]] and [[bioinformatics]], and in particular to the analysis of [[microarray]] data.

=== Expert witness === Speed was an [[expert witness]] for the defense of O.J. Simpson at the trial for the [[O. J. Simpson murder case]],<ref>[https://www.usatoday.com/news/index/nns30.htm Defense witness list for the O.J. Simpson civil trial], published by [[USA Today]].</ref> as well as an expert witness in the [[David Baltimore#Imanishi-Kari case|Imanishi-Kari case]], an affair of alleged [[scientific misconduct]] which involved biologist [[David Baltimore]].<ref>[[Daniel Kevles]] (1998), ''The Baltimore Case: A Trial of Politics, Science, and Character.'' New York: W.W. Norton & Co., Inc. 345–348.</ref> Much earlier in his career, he was an expert defence witness in the 1966 trial of [[Ronald Ryan]], the last person executed in Australia; however, his evidence that Ryan must have been at least 2.55 metres tall (he was only 1.73 metres) to fire the fatal shot failed to sway the jury.<ref>[http://www.bluemountainsgazette.com.au/story/1877494/professors-brilliant-career-from-murder-trials-to-top-honour/?cs=8 Blue Mountains Gazette, 31 October 2013]. Retrieved 21 October 2017</ref>

==Awards and honours== In 1989 Speed was elected as a [[Fellow of the American Statistical Association]].<ref>[http://www.amstat.org/awards/fellowslist.cfm View/Search Fellows of the ASA] {{Webarchive|url=https://web.archive.org/web/20160616161612/https://www.amstat.org/awards/fellowslist.cfm |date=16 June 2016 }}, accessed 2016-11-19.</ref> Speed was [[president of the Institute of Mathematical Statistics]] in 2004.<ref>[http://www.imstat.org/officials/past_officials.html List of Past Executive Committee Members] {{Webarchive|url=https://web.archive.org/web/20080220073443/http://www.imstat.org/officials/past_officials.html |date=20 February 2008 }}, on the Web site of the [[Institute of Mathematical Statistics]].</ref> In 2002, he received the [[E. J. G. Pitman|Pitman]] medal.<ref name=pitman>{{Cite journal | doi = 10.1111/1467-842X.00255| title = Pitman Medal for 2002 awarded to Terry Speed| journal = Australian & New Zealand Journal of Statistics| volume = 45| pages = 1–4| year = 2003| s2cid = 247695703}}</ref> In 2009 he was awarded a [[NHMRC]] Australia Fellowship.<ref>[http://www.wehi.edu.au/site/latest_news/by_year/2009/P39/ Australia Fellowship for WEHI’s Professor Terry Speed] {{webarchive|url=https://web.archive.org/web/20110727004222/http://www.wehi.edu.au/site/latest_news/by_year/2009/P39/ |date=27 July 2011 }}, press release by [[WEHI]] on 29 Jan 2009.</ref> On 30 October 2013, he received the Australian [[Prime Minister's Prize for Science]].<ref>{{cite web |url=http://www.innovation.gov.au/science/InspiringAustralia/PrimeMinistersPrizesforScience/Recipients/2013PrizeRecipients/Pages/2013PrimeMinistersPrizeforScience.aspx |title=2013 Prime Minister's Prize for Science |access-date=2013-10-30 |url-status=dead |archive-url=https://web.archive.org/web/20140212065726/http://www.innovation.gov.au/science/InspiringAustralia/PrimeMinistersPrizesforScience/Recipients/2013PrizeRecipients/Pages/2013PrimeMinistersPrizeforScience.aspx |archive-date=12 February 2014 |df=dmy-all }}</ref><ref>{{cite web |author=Latika Bourke| url=https://www.abc.net.au/news/2013-10-30/pms-science-prize-awarded-terry-speed/5058200 |title=Statistician Terry Speed wins Prime Minister's science prize for cancer research|website=[[ABC News (Australia)|ABC News]]|access-date=2021-08-27|date=30 October 2013 }}</ref> Speed was elected a Fellow of the [[Royal Society]] (FRS) of London in 2013. His nomination reads: {{centered pull quote|Speed is regarded internationally as THE expert on the analysis of microarray data. This results partly from the sheer ingenuity of his work, and in part it is due to his commitment to working closely with biomedical scientists, enabling him to appreciate first-hand the biological challenges and the consequent requirements of new methodology. Microarrays are now being replaced by short-read [[DNA sequencing]], but Speed continues to contribute new ideas for the new technology. At other time in his career, Speed has made seminal contributions to [[bioinformatics]], [[statistical genetics]], the analysis of designed experiments, graphical models and [[Bayesian network|Bayes networks]].<ref name=royal/>}}

==Personal life== Speed married Freda Elizabeth (Sally) Pollard in 1964.<ref name=whoswho/>

==References== <references/>

==External links== * [http://magazine.amstat.org/blog/2016/09/01/terryspeedinterview/ Interview with Terry Speed], by [[Jean Yang]]. Amstat News, 1 September 2016.

{{DEFAULTSORT:Speed, Terry}} [[Category:1943 births]] [[Category:Living people]] [[Category:Presidents of the Institute of Mathematical Statistics]] [[Category:Fellows of the Australian Academy of Science]] [[Category:Australian fellows of the Royal Society]] [[Category:Australian statisticians]] [[Category:Australian bioinformaticians]]  [[Category:WEHI alumni]] [[Category:Fellows of the American Statistical Association]] [[Category:WEHI staff]]