THOC2

{{Short description|Protein-coding gene in the species Homo sapiens}} {{Infobox_gene}} '''THO complex subunit 2''' is a protein that in humans is encoded by the ''THOC2'' gene.<ref name="pmid11979277">{{cite journal |vauthors=Strasser K, Masuda S, Mason P, Pfannstiel J, Oppizzi M, Rodriguez-Navarro S, Rondon AG, Aguilera A, Struhl K, Reed R, Hurt E | title = TREX is a conserved complex coupling transcription with messenger RNA export | journal = Nature | volume = 417 | issue = 6886 | pages = 304–8 |date=May 2002 | pmid = 11979277 | doi = 10.1038/nature746 | bibcode = 2002Natur.417..304S | s2cid = 1112194 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: THOC2 THO complex 2| url = https://www.ncbi.nlm.nih.gov/gene?Db=gene&Cmd=ShowDetailView&TermToSearch=57187}}</ref>

THO2 is part of the TREX (transcription/export) complex, which includes TEX1 (MIM 606929), HPR1 (MIM 606930), ALY (MIM 604171), and UAP56 (MIM 606390).[supplied by OMIM]<ref name="entrez" />

==References== {{reflist}}

==Further reading== {{refbegin | 2}} *{{cite journal | author=Coffey AJ |title=Host response to EBV infection in X-linked lymphoproliferative disease results from mutations in an SH2-domain encoding gene |journal=Nat. Genet. |volume=20 |issue= 2 |pages= 129–35 |year= 1998 |pmid= 9771704 |doi= 10.1038/2424 |name-list-style=vanc| author2=Brooksbank RA | author3=Brandau O | display-authors=3 | last4=Oohashi | first4=Toshitaka | last5=Howell | first5=Gareth R. | last6=Bye | first6=Jacqueline M. | last7=Cahn | first7=Anthony P. | last8=Durham | first8=Jillian | last9=Heath | first9=Paul |s2cid=9347438 }} *{{cite journal | author=Strausberg RL |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 |name-list-style=vanc| author2=Feingold EA | author3=Grouse LH | display-authors=3 | last4=Derge | first4=JG | last5=Klausner | first5=RD | last6=Collins | first6=FS | last7=Wagner | first7=L | last8=Shenmen | first8=CM | last9=Schuler | first9=GD |bibcode=2002PNAS...9916899M |doi-access=free }} *{{cite journal | author=Ota T |title=Complete sequencing and characterization of 21,243 full-length human cDNAs |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 |name-list-style=vanc| author2=Suzuki Y | author3=Nishikawa T | display-authors=3 | last4=Otsuki | first4=Tetsuji | last5=Sugiyama | first5=Tomoyasu | last6=Irie | first6=Ryotaro | last7=Wakamatsu | first7=Ai | last8=Hayashi | first8=Koji | last9=Sato | first9=Hiroyuki | doi-access=free }} *{{cite journal | author=Beausoleil SA |title=Large-scale characterization of HeLa cell nuclear phosphoproteins |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=101 |issue= 33 |pages= 12130–5 |year= 2004 |pmid= 15302935 |doi= 10.1073/pnas.0404720101 | pmc=514446 |name-list-style=vanc| author2=Jedrychowski M | author3=Schwartz D | display-authors=3 | last4=Elias | first4=JE | last5=Villén | first5=J | last6=Li | first6=J | last7=Cohn | first7=MA | last8=Cantley | first8=LC | last9=Gygi | first9=SP |bibcode=2004PNAS..10112130B |doi-access=free }} *{{cite journal | author=Masuda S |title=Recruitment of the human TREX complex to mRNA during splicing |journal=Genes Dev. |volume=19 |issue= 13 |pages= 1512–7 |year= 2005 |pmid= 15998806 |doi= 10.1101/gad.1302205 | pmc=1172058 |name-list-style=vanc| author2=Das R | author3=Cheng H | display-authors=3 | last4=Hurt | first4=E | last5=Dorman | first5=N | last6=Reed | first6=R }} *{{cite journal | author=Kimura K |title=Diversification of transcriptional modulation: Large-scale identification and characterization of putative alternative promoters of human genes |journal=Genome Res. |volume=16 |issue= 1 |pages= 55–65 |year= 2006 |pmid= 16344560 |doi= 10.1101/gr.4039406 | pmc=1356129 |name-list-style=vanc| author2=Wakamatsu A | author3=Suzuki Y | display-authors=3 | last4=Ota | first4=T | last5=Nishikawa | first5=T | last6=Yamashita | first6=R | last7=Yamamoto | first7=J | last8=Sekine | first8=M | last9=Tsuritani | first9=K }} *{{cite journal | author=Beausoleil SA |title=A probability-based approach for high-throughput protein phosphorylation analysis and site localization |journal=Nat. Biotechnol. |volume=24 |issue= 10 |pages= 1285–92 |year= 2006 |pmid= 16964243 |doi= 10.1038/nbt1240 |name-list-style=vanc| author2=Villén J | author3=Gerber SA | display-authors=3 | last4=Rush | first4=John | last5=Gygi | first5=Steven P |s2cid=14294292 }} *{{cite journal | author=Olsen JV |title=Global, in vivo, and site-specific phosphorylation dynamics in signaling networks |journal=Cell |volume=127 |issue= 3 |pages= 635–48 |year= 2006 |pmid= 17081983 |doi= 10.1016/j.cell.2006.09.026 |name-list-style=vanc| author2=Blagoev B | author3=Gnad F | display-authors=3 | last4=Macek | first4=Boris | last5=Kumar | first5=Chanchal | last6=Mortensen | first6=Peter | last7=Mann | first7=Matthias | doi-access=free }} {{refend}}