{{short description|Healthcare analytics company based in United States}} {{Infobox company | name = Surgisphere | logo = Surgisphere company logo.png | type = Private | industry = Healthcare analytics | predecessor = <!-- or: | predecessors = --> | successor = <!-- or: | successors = --> | founded = 2008<ref name="Bloomberg">{{cite web |title=Surgisphere Corp |url=https://www.bloomberg.com/profile/company/0691925D:US |website=Bloomberg |access-date=11 June 2020}}</ref> | founder = <!-- or: | founders = --> | hq_location_city = Palatine, Illinois | hq_location_country = US<ref name=Scientist30May>{{cite web |last1=Offord |first1=Catherine |title=Disputed Hydroxychloroquine Study Brings Scrutiny to Surgisphere |url=https://www.the-scientist.com/news-opinion/disputed-hydroxychloroquine-study-brings-scrutiny-to-surgisphere-67595 |website=The Scientist |access-date=3 June 2020 |archive-url=https://web.archive.org/web/20200603131224/https://www.the-scientist.com/news-opinion/disputed-hydroxychloroquine-study-brings-scrutiny-to-surgisphere-67595 |archive-date=3 June 2020 |date=30 May 2020}}</ref> | area_served = <!-- or: | areas_served = --> | key_people = Sapan Desai (CEO and founder) | products = | owner = <!-- or: | owners = --> | num_employees = 11 | num_employees_year = <!-- Year of num_employees data (if known) --> | parent = | website = {{URL|https://surgisphere.com/}} {{dead link|date=June 2020}} }} '''Surgisphere''' is an American healthcare analytics company established in 2008 by Sapan Desai. Originally a textbook marketing company, it came under scrutiny in May 2020 after it provided large datasets of COVID-19 patients that were subsequently found to be unreliable. The questionable data were used in studies published in ''The Lancet'' and ''The New England Journal of Medicine'' in May 2020, suggesting that COVID-19 patients on hydroxychloroquine had a "significantly higher risk of death". In light of these studies, the World Health Organization decided to temporarily halt global trials of the drug hydroxychloroquine to treat COVID-19. After the studies were retracted, the WHO trials were resumed and then discontinued shortly after.
==History== Surgisphere was established in 2008<ref name="Bloomberg"/> by Sapan Desai, then a medical resident, to market medical textbooks to medical students. Fake five-star reviews on Amazon from accounts impersonating actual physicians were found.<ref name="offord">{{Cite web |last=Catherine Offord |date=2020-05-30 |title=Disputed Hydroxychloroquine Study Brings Scrutiny to Surgisphere |url=https://www.the-scientist.com/news-opinion/disputed-hydroxychloroquine-study-brings-scrutiny-to-surgisphere-67595 |access-date=2020-06-08 |website=The Scientist Magazine® |language=en}}</ref> Desai became a vascular surgeon and worked at Northwest Community Hospital.<ref name="Davey-28May2020"/><ref name="medi_AStu">{{Cite web |title= A Study Out of Thin Air |first1=James|last1=Todaro |work=MedicineUncensored |date= 29 May 2020 |access-date= 3 June 2020 |url= https://www.medicineuncensored.com/a-study-out-of-thin-air |quote=Dr. Desai appears to be the founder of Surgisphere, which was formed in 2007. A PubMed search for “Sapan Desai” shows 39 medical publications in the last five years. With the exception of the two very recent COVID-19 papers, the Surgisphere database does not appear to have been used in any of the other 37 publications. Why would the founder of Surgisphere have access to one of the largest repositories of real-time patient data, but not use it until publishing on COVID-19? If we ignore the image of multiple shell corporations enshrouding a hastily organized Surgisphere Corporation and stick to analyzing the COVID-19 data from the Lancet study, the findings are even less reassuring.}}</ref><ref name= "even_DrSa">{{Cite web |title=Dr Sapan Desai, United States of America |work= World Hospital Congress | publisher = Iceberg events |access-date=3 June 2020 |url= https://event.icebergevents.com.au/whc2018/speakers/dr-sapan-desai-united-states-of-america |quote=Sapan Desai, MD, PhD, MBA is President and Chief Executive Officer of the Surgisphere Corporation, a medical education and healthcare data analytics company with hundreds of clients around the world. He has held multiple physician leadership roles in clinical practice, including serving as the Vice Chairman for Research at Southern Illinois University, Director of Quality at Memorial Medical Center, and Director of Performance Improvement at Northwest Community Hospital. Dr. Desai is a certified lean six sigma master black belt, and a certified professional in healthcare quality. He is the recipient of the international grand prize in healthcare quality by the International Hospital Federation in 2015.}}</ref>
Surgisphere had three subsidiaries: Surgical Outcomes Collaborative, Vascular Outcomes and Quartz Clinical.<ref name="medi_AStu"/> From 2010 to 2013 it published an online medical journal, the ''Journal of Surgical Radiology''.<ref name=Scientist30May/><ref name="medi_AStu"/> It ceased publication despite having claimed to accrue 50,000 subscribers because Desai "ran out of time".<ref name="offord"/>
In June 2020 Desai's spokesperson said Surgisphere had 11 employees and had been compiling a global hospital records database since 2008.<ref name="kelly">{{Cite news |last1=Servick |first1=Kelly |last2=Enserink |first2=Martin |date=2020-06-05 |title=The pandemic's first major research scandal erupts |language=en |volume=368 |pages=1041–1042 |work=Science |issue=6495 |url=https://www.science.org/doi/10.1126/science.368.6495.1041 |access-date=2020-07-07 |doi=10.1126/science.368.6495.1041 |issn=0036-8075 |pmid=32499418}}</ref> In its promotional material and press releases, Surgisphere claimed to have a cloud-based healthcare data analytics platform and to be "leveraging... its global research network and advanced machine learning" using decision tree analysis.<ref>{{Cite news |last=Zaidisays |first=Al |date=2020-05-27 |title=Surgisphere's COVID-19 Tools are Deadly Fraud |language=en |url=https://iowaclimate.org/2020/05/26/surgispheres-covid-19-tools-are-deadly-fraud/ |access-date=2020-07-07}}</ref>
After the retractions of two studies in June 2020, company social media accounts were deleted,<ref>{{cite news|last1=Hopkins|first1=Jared S.|last2=Gold|first2=Russell|date=11 June 2020|title=The Big-Data Mystery Behind Retracted Covid-19 Studies of Hydroxychloroquine, Other Drugs|work=Wall Street Journal|url=https://www.wsj.com/articles/the-big-data-mystery-behind-retracted-covid-19-studies-of-hydroxychloroquine-other-drugs-11591867981|access-date=17 June 2020}}</ref> and on 15 June 2020, the company website was taken offline.<ref name="ower">{{cite web|last1=Owermohle|first1=Sarah|date=16 June 2020|title=Hydroxychloroquine is out|url=https://www.politico.com/newsletters/prescription-pulse/2020/06/16/hydroxychloroquine-is-out-489540|access-date=17 June 2020|website=Politico}}</ref>
==COVID-19 misconduct{{anchor|COVID-19}}== {{further|Chloroquine and hydroxychloroquine during the COVID-19 pandemic#WHO trial}}
===Diagnostic tool=== Starting in March 2020, Surgisphere promoted a "rapid diagnostic tool" for COVID-19, which it said was in use by over 1000 hospitals.<ref name="thedisp">{{Cite web |title=Disputed Hydroxychloroquine Study Brings Scrutiny to Surgisphere |first1=Catherine|last1=Offord |work=The Scientist Magazine® |date=30 May 2020 |access-date=3 June 2020 |url= https://www.the-scientist.com/news-opinion/disputed-hydroxychloroquine-study-brings-scrutiny-to-surgisphere-67595 |quote=James Watson, a senior scientist at the Mahidol Oxford Tropical Medicine Research Unit in Thailand, says he has doubts that any research organization would have been able to obtain such detailed records for so many people in Africa so quickly. He outlined this and concerns about multiple other aspects of the study in the open letter, which includes 17 signatories based at institutions in Africa.}}</ref><ref>{{cite tweet |author= James Watson |user=jwato_watson |number=1265603863551389697 |date=27 May 2020 |title=As you might expect, it's a different story... conclusion: a prediction tool that is basically just linear regression and estimates age-dependent mortality that conflicts with a very large and reliable (we know where the data came from!) study. Wonderful AI/ML companies..!(6/n)}}</ref> The African Federation for Emergency Medicine(AFEM) had promoted the COVID-19 Severity Scoring Tool for use in 26 countries and some institutions had started validation studies. On 5 June 2020, following the scandal about the Lancet and NEJM articles, AFEM recommended that the tool no longer be used.<ref>{{cite web |last1=Offord |first1=Catherine |title=Surgisphere Fallout Hits African Nonprofit's COVID-19 Efforts |url=https://www.the-scientist.com/news-opinion/surgisphere-fallout-hits-african-nonprofits-covid-19-efforts--67617 |website=The Scientist Magazine |access-date=19 June 2020 |language=en |date=7 June 2020}}</ref>
===Ivermectin preprint=== In April 2020, Desai ''et al''. published a paper based on purported Surgisphere data which suggested ivermectin reduced COVID-19 mortality.<ref name=Servicketal/> It was described as a "retrospective matched-control study of coronavirus patients using a real-time hospitalization database". It was published as a preprint but was retracted at the end of May.<ref name="derek">{{Cite news |last1=Lowe |first1=Derek |date=11 May 2020|title=What's Up With Ivermectin? |work=science.com |language=en-US |url=https://www.science.org/content/blog-post/what-s-ivermectin |access-date=4 June 2020}}</ref><ref name="Piller-4June2020"/><ref name=":0">{{Cite web|last=|first=|date=2020-06-16|title=Surgisphere Sows Confusion About Another Unproven COVID-19 Drug|url=https://www.the-scientist.com/news-opinion/surgisphere-sows-confusion-about-another-unproven-covid19-drug-67635|access-date=2020-07-09|website=The Scientist Magazine®|language=en}}</ref> Several Latin American government health organizations recommended ivermectin as a COVID-19 treatment based, in part, on this preprint; these recommendations were later denounced by the Pan American Health Organization.<ref name=":0" /><ref>{{Cite web|title=Lancet, NEJM Retract Surgisphere Studies on COVID-19 Patients|url=https://www.the-scientist.com/news-opinion/lancet-retracts-surgispheres-study-on-hydroxychloroquine-67613|access-date=2021-07-23|website=The Scientist Magazine®|language=en}}</ref>
===Lancet and NEJM articles=== Surgisphere provided dubious data used for studies of COVID-19 that were published in ''The Lancet''<ref name="mehra">{{cite journal |last1=Mehra|first1=MR|last2= Desai |first2=SS|last3= Ruschitzka |first3= F |last4=Patel|first4=AN |date= May 2020|title=Hydroxychloroquine or chloroquine with or without a macrolide for treatment of COVID-19: a multinational registry analysis |journal=Lancet |doi= 10.1016/S0140-6736(20)31180-6 |pmid= 32450107 |pmc=7255293 }} [https://www.sciencedaily.com/releases/2020/05/200522113712.htm Lay source]{{Retracted|doi=10.1016/S0140-6736(20)31324-6|pmid=32511943|http://retractionwatch.com/2020/06/02/nejm-places-expression-of-concern-on-controversial-study-of-drugs-for-covid-19/ ''Retraction Watch''|http://retractionwatch.com/retracted-coronavirus-covid-19-papers/ ''Retraction Watch''|intentional=yes}}</ref> and ''The New England Journal of Medicine'' (''NEJM'') in May 2020.<ref name="Guardian3June">{{cite news |last1=Davey |first1=Melissa |last2= Kirchgaessner |first2=Stephanie |last3= Boseley |first3=Sarah |title=Governments and WHO changed Covid-19 policy based on suspect data from tiny US company |url= https://www.theguardian.com/world/2020/jun/03/covid-19-surgisphere-who-world-health-organization-hydroxychloroquine |access-date=3 June 2020 |work=Guardian |date=3 June 2020}}</ref><ref>{{Cite web|last1=Piller|first1=Charles|date=2020-06-08|title=Who's to blame? These three scientists are at the heart of the Surgisphere COVID-19 scandal|url=https://www.science.org/content/article/whos-blame-these-three-scientists-are-heart-surgisphere-covid-19-scandal|access-date=2021-07-23|website=Science {{!}} AAAS|language=en}}</ref> The Lancet study claimed that the dataset of hospital records showed that patients taking hydroxychloroquine were more likely to die in hospital, and prompted the World Health Organization to halt global trials of the drug to treat COVID-19.<ref name="Davey-28May2020">{{cite news |last1=Davey |first1=Melissa |title=Questions raised over hydroxychloroquine study which caused WHO to halt trials for Covid-19 |url=https://www.theguardian.com/science/2020/may/28/questions-raised-over-hydroxychloroquine-study-which-caused-who-to-halt-trials-for-covid-19 |access-date=3 June 2020 |work=Guardian |date=28 May 2020}}</ref><ref name=Servicketal>{{cite web |url=https://www.science.org/content/article/mysterious-company-s-coronavirus-papers-top-medical-journals-may-be-unraveling |title=A mysterious company's coronavirus papers in top medical journals may be unraveling |first1=Kelly|last1=Servick|first2=Martin|last2=Enserink |date=2 June 2020 |website=Science |publisher=AAAS |access-date=June 3, 2020}}</ref><ref>{{Cite web|title=Was the Surgisphere case a one-off, or does it highlight the bigger systemic problem of research fraud?|url=https://www.transparency.org.uk/surgisphere-covid-19-coronavirus-research-fraud-issue-lancet-nejm|access-date=2021-07-23|website=Transparency International UK|language=en}}</ref> The ''NEJM'' study claimed that hospital data records showed that COVID-19 patients were not harmed by treatment with ACE inhibitors and angiotensin-receptor blockers.<ref name="Guardian3June" /><ref>{{Cite web|title=Could the Surgisphere Retractions Debacle Happen Again?|url=http://www.medscape.com/viewarticle/953653|access-date=2021-07-23|website=Medscape|language=en}}</ref><ref>{{Cite web|date=2020-06-03|title=Surgisphere Data Used in Two COVID Studies Called Into Question|url=https://www.medpagetoday.com/infectiousdisease/covid19/86861|access-date=2021-07-23|website=www.medpagetoday.com|language=en}}</ref>
The dataset from the alleged 1200 hospitals had many errors, including the listing of an Asian hospital as being in Australia, and no indications of how Surgisphere could collect the data, and was widely criticised.<ref name="pubp_PubP">{{Cite journal |title=PubPeer - Hydroxychloroquine or chloroquine with or without a macrolid... |journal=Lancet |year= 2020|access-date=3 June 2020 |url= https://pubpeer.com/publications/71DA593B9943638F1ADE6F80696914|doi=10.1016/s0140-6736(20)31180-6|pmid= 32450107|issn=0140-6736|last1= Mehra|first1= M. R.|last2= Desai|first2= S. S.|last3= Ruschitzka|first3= F.|last4= Patel|first4= A. N.|pmc= 7255293}}</ref><ref name="stat_Doub">{{Cite web |title=Doubts about that article claiming that hydroxychloroquine/chloroquine is killing people « Statistical Modeling, Causal Inference, and Social Science |first1=Andrew|last1=Gelman |work=statmodeling.stat.columbia.edu |date=24 May 2020|access-date=3 June 2020 |url= https://statmodeling.stat.columbia.edu/2020/05/24/doubts-about-that-article-claiming-that-hydroxychloroquine-chloroquine-is-killing-people/}}</ref><ref name="stat_Hydr">{{Cite web |title=Hydroxychloroquine update: Statistical Modeling, Causal Inference, and Social Science |first1=Andrew|last1=Gelman|work=statmodeling.stat.columbia.edu |date=25 May 2020|access-date=3 June 2020 |url= https://statmodeling.stat.columbia.edu/2020/05/25/hydroxychloroquine-update/}}</ref><ref name="Davey-28May2020"/> As a result, on 28 May over 200 researchers and doctors from various countries published "An open letter to Richard Horton, editor-in-chief of ''The Lancet'', regarding Mehra ''et al''", stating "Both the numbers of cases and deaths, and the detailed data collection, seem unlikely."<ref name="Zenodo">{{cite journal |title=An open letter to Mehra et al and The Lancet |url=https://zenodo.org/record/3871094 |website=Zenodo |year=2020 |doi=10.5281/zenodo.3871094 |access-date=5 June 2020|author1=James Watson On The Behalf Of 201 Signatories }}</ref> ''Science Magazine'' said critics had "pointed out many red flags in the Lancet paper, including the astonishing number of patients involved and details about their demographics and prescribed dosing that seem implausible."<ref name=Servicketal/><ref name=Guardian3June/> One of the signatories, Adrian Hernandez of the Duke Clinical Research Institute, said "''the biggest thing that raised a red flag was that there was such a large database across more than 600 hospitals, and no one had really known about its existence''".<ref name="nyti_Scie">{{Cite web |title=Scientists Question Validity of Major Hydroxychloroquine Study |author=Roni Caryn Rabin |work=The New York Times |date=29 May 2020 |access-date=3 June 2020 |url= https://www.nytimes.com/2020/05/29/health/coronavirus-hydroxychloroquine.html |quote=The experts who wrote The Lancet also criticized the study’s methodology and the authors’ refusal to identify any of the hospitals that contributed patient data, or to name the countries where they were located. The company that owns the database is Surgisphere, based in Chicago.}}</ref>
On 3 June 2020, ''The Lancet'' and the ''NEJM'' released online "expressions of concern" about the published studies,<ref name="thel_Expr">{{Cite journal |title=Expression of concern: Hydroxychloroquine or chloroquine with or without a macrolide for treatment of COVID-19: a multinational registry analysis |journal=The Lancet |date=3 June 2020|doi=10.1016/S0140-6736(20)31290-3|url= |volume= 395|issue= 10240|pages= e102|pmid= 32504543|pmc= 7269709 |last1=The Lancet Editors }}</ref><ref name="nejm_Expr">{{Cite journal |title=Expression of Concern: Mehra MR et al. Cardiovascular Disease, Drug Therapy, and Mortality in Covid-19.|first1=Eric J.|last1=Rubin M.D, Ph.D|date=2 June 2020|doi=10.1056/NEJMe2020822|journal=New England Journal of Medicine |volume=382|issue=25|page=2464|pmid=32484612|pmc=7269012|s2cid=219174075|doi-access=free}}</ref> and on 4 June the ''Lancet'' paper was retracted by Mehra, Ruschitzka, and Amit Patel, all authors except Desai. In their retraction, the three wrote Surgisphere had not transferred "the full dataset, client contracts, and the full ISO audit report to their servers for analysis as such transfer would violate client agreements and confidentiality requirements", preventing reviewers from conducting an independent and private peer review. The three authors said:
:"We can never forget the responsibility we have as researchers to scrupulously ensure that we rely on data sources that adhere to our high standards. Based on this development, we can no longer vouch for the veracity of the primary data sources. Due to this unfortunate development, the authors request that the paper be retracted."<ref>{{Cite journal|vauthors=Mehra MR, Ruschitzka F, Patel AN|date=June 2020|title=Retraction: "Hydroxychloroquine or chloroquine with or without a macrolide for treatment of COVID-19: a multinational registry analysis"|journal=Lancet|volume=395|issue=10240|page=1820|doi=10.1016/S0140-6736(20)31324-6 |pmid=32511943|pmc=7274621|url=|doi-access=free}}</ref>
On 4 June, ''The Lancet'' retracted the study,<ref name=retraction>{{cite journal|title=Retraction: "Hydroxychloroquine or chloroquine with or without a macrolide for treatment of COVID-19: a multinational registry analysis"|date=4 June 2020|journal=The Lancet|doi=10.1016/S0140-6736(20)31324-6|last1=Mehra|first1=Mandeep R.|last2=Ruschitzka|first2=Frank|last3=Patel|first3=Amit N.|volume=395|issue=10240|page=1820|pmid=32511943|pmc=7274621}}</ref><ref>{{cite news | last1=Boseley | first1=Sarah | last2=Davey | first2=Melissa | title=Covid-19: Lancet retracts paper that halted hydroxychloroquine trials | website=The Guardian | date=4 June 2020 | url=http://www.theguardian.com/world/2020/jun/04/covid-19-lancet-retracts-paper-that-halted-hydroxychloroquine-trials | access-date=4 June 2020}}</ref> as did the ''NEJM''.<ref>{{cite journal |title=Retraction: Cardiovascular Disease, Drug Therapy, and Mortality in Covid-19. N Engl J Med. DOI: 10.1056/NEJMoa2007621. |journal=The New England Journal of Medicine |date=4 June 2020 |doi=10.1056/NEJMc2021225 |doi-access=free |last1=Mehra |first1=Mandeep R. |last2=Desai |first2=Sapan S. |last3=Kuy |first3=Sreyram |last4=Henry |first4=Timothy D. |last5=Patel |first5=Amit N. |volume=382 |issue=26 |page=2582 |pmid=32501665 |pmc=7274164 }}</ref><ref name="Piller-4June2020">{{cite news |last1=Piller |first1=Charles |last2=Servick |first2=Kelly |title=Two elite medical journals retract coronavirus papers over data integrity questions |url=https://www.science.org/content/article/two-elite-medical-journals-retract-coronavirus-papers-over-data-integrity-questions |access-date=5 June 2020 |work=Science |date=4 June 2020}}</ref><ref name="WSJ study retracted">{{cite news |last1=Hopkins |first1=Jared S. |last2=Gold |first2=Russell |title=Hydroxychloroquine Studies Tied to Data Firm Surgisphere Retracted|url=https://www.wsj.com/articles/authors-retract-study-that-found-risks-of-using-antimalaria-drug-against-covid-19-11591299329 |access-date=5 June 2020 |work=The Wall Street Journal |date=4 June 2020}}</ref> In the meantime, on 3 June, the WHO resumed its hydroxychloroquine drug trials.<ref name="Mancini-3Jun2020">{{cite news |last1=Mancini |first1=Donato Paolo |last2=Kuchler |first2=Hannah |title=WHO restarts drug trial as doubts grow over clinical data |url=https://www.ft.com/content/12186877-46f5-44bd-8b6c-18d41dbfa32a |access-date=5 June 2020 |work=Financial Times |date=3 June 2020}}</ref>
On 6 June 2020, NHS Scotland told the ''Financial Times'' that they had "no current or past contractual arrangement" with Surgisphere, nor was the company an approved supplier, nor had it ever had access to data, despite Surgisphere stating it had "collaborated" with the NHS. Surgisphere's website had a picture of Queen Elizabeth University Hospital, an NHS hospital in Glasgow.<ref name="app._FT">{{Cite web |title=Edinburgh disavows Surgisphere claims of co-operation with NHS Scotland |author=Mure Dickie |author2=Donato Paolo Mancini |author3=Hannah Kuchler |work=Financial Times |date=6 June 2020 |access-date=8 June 2020 |url= https://app.ft.com/cms/s/09cde59c-26f8-4248-898f-64c7cdd7c66c.html}}</ref>
On 7 June 2020, fellow author Amit Patel's position with the University of Utah was terminated over the journal retractions. Patel is Desai's brother-in-law.<ref name="stat_Rese">{{Cite web |title=Researcher has faculty appointment terminated after Lancet retraction |author=Matthew Herper |author2=Kate Sheridan |work=STAT |date=7 June 2020 |access-date=8 June 2020 |url= https://www.statnews.com/2020/06/07/researcher-involved-in-retracted-lancet-study-has-faculty-appointment-terminated-as-details-in-scandal-emerge/ |quote=The University of Utah has “mutually agreed” to terminate the faculty appointment of Amit Patel, who was among the authors of two retracted papers on Covid-19 and who appears to have played a key role in involving a little-known company that has ignited a firestorm of controversy. }}</ref>
Richard Horton, editor-in-chief of ''The Lancet'', called the paper "a fabrication" and "a monumental fraud". Eric Rubin, editor-in-chief of ''NEJM'', said "We shouldn’t have published this".<ref name="nyti_TheP">{{Cite web |title=The Pandemic Claims New Victims: Prestigious Medical Journals |author=Roni Caryn Rabin |work=The New York Times |date=14 June 2020 |access-date=18 June 2020 |url= https://www.nytimes.com/2020/06/14/health/virus-journals.html}}</ref>
==General legitimacy== A July 2020 article in ''New York Times'' described an employee extracting data manually to create a spreadsheet for Surgisphere's QuartzClinical. She was "surprised" by claims of a massive data store, stating she knew of only a single hospital that had signed a contract with the company; the May 1 paper in ''NEJM'' claimed to use data from 169 hospitals across the globe, and the May 22 paper in ''The Lancet''.<ref name="nytcrsd">{{Cite web |title=The Doctor Behind the Disputed Covid Data |author=Ellen Gabler |author2=Roni Caryn Rabin |work=The New York Times |date=27 July 2020 |access-date=27 July 2020 |url= https://www.nytimes.com/2020/07/27/science/coronavirus-retracted-studies-data.html}}</ref>
A parallel investigation by the British newspaper ''The Guardian'' revealed that several of Surgisphere's employees had little or no scientific background; one employee appeared to be a science fiction author while another, listed as a marketing executive, was an adult model. ''The Guardian'' also found that Surgisphere's LinkedIn page has fewer than 100 followers and in late May 2020 listed only six employees. It also found that the company had almost no online presence and that its Twitter account had made no posts from October 2017 to March 2020.<ref name="Guardian3June"/>
Elisabeth Bik ''et al.'' analyzed one of Desai's early first author papers and found apparent evidence of image manipulation.<ref>[https://scienceintegritydigest.com/2020/06/06/the-surgisphere-founder-and-the-melba-toast-figure/ The Surgisphere Founder and the Melba Toast figure], ''Science Integrity Digest'', June 6, 2020.</ref><ref name="Davey Kirchgaessner 2020">{{cite web | last1=Davey | first1=Melissa | last2=Kirchgaessner | first2=Stephanie | title=Surgisphere: mass audit of papers linked to firm behind hydroxychloroquine Lancet study scandal | website=the Guardian | date=2020-06-10 | url=http://www.theguardian.com/world/2020/jun/10/surgisphere-sapan-desai-lancet-study-hydroxychloroquine-mass-audit-scientific-papers | access-date=2020-06-10}}</ref>
== References == <references />
==External links== * {{LinkedIn page|company/surgisphere}} * [https://www.youtube.com/watch?v=ZVoYZXPUS7w&feature=youtu.be&t=65 Sapan Desai interview about the studies] on TRT World * [https://statmodeling.stat.columbia.edu/2020/06/15/surgisphere-scandal-legacy-media-lancet-still-dont-get-it/ Surgisphere scandal: Lancet still doesn’t get it] by Andrew Gelman
Category:Health care companies of the United States Category:Analytics companies Category:Companies based in Cook County, Illinois Category:Scientific misconduct incidents Category:Internet properties disestablished in 2020 Category:Internet properties established in 2008 Category:American companies established in 2008 Category:American companies disestablished in 2020 Category:2008 establishments in Illinois Category:2020 disestablishments in Illinois