{{Update|date=December 2024|reason=Needs updating to fit current MOS}}
'''Sup45p''' is the ''Saccharomyces cerevisiae'' (a yeast) eukaryotic translation termination factor. More specifically, it is the yeast eukaryotic release factor 1 (eRF1). Its job is to recognize stop codons in RNA and bind to them. It binds to the Sup35p protein and then takes on the shape of a tRNA molecule so that it can safety incorporate itself into the A site of the Ribosome to disruptits flow and "release" the protein and end translation.<ref>{{Cite journal | last1 = Paushkin | first1 = S. V. | last2 = Kushnirov | first2 = V. V. | last3 = Smirnov | first3 = V. N. | last4 = Ter-Avanesyan | first4 = M. D. | title = Interaction between yeast Sup45p (eRF1) and Sup35p (eRF3) polypeptide chain release factors: Implications for prion-dependent regulation | journal = Molecular and Cellular Biology | volume = 17 | issue = 5 | pages = 2798–2805 | year = 1997 | pmid = 9111351 | pmc = 232131 | doi=10.1128/mcb.17.5.2798 }}</ref>
== Notes == {{Reflist}}
Category:Saccharomyces cerevisiae genes Category:Protein biosynthesis
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