{{distinguish|text=Seine, a river in France}}
'''Saine''' is a surname. Notable people with this surname include: * Brandon Saine (born 1988), American football player * Lori Saine, American politician * Pap Saine, Gambian newspaper publisher * Thomas P. Saine (1941-2013), American educator
== See also == * Sain (disambiguation), which also lists persons with the name ''Sain''
{{surname}}