ST8SIA6

{{Short description|Protein-coding gene in the species Homo sapiens}} {{Infobox_gene}}

'''ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6''' is a protein that in humans is encoded by the ST8SIA6 gene. <ref name="entrez"> {{cite web | title = Entrez Gene: ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6 | url = https://www.ncbi.nlm.nih.gov/gene/338596 | access-date = 2017-02-02 }}</ref>

==Function==

Sialic acid is a key determinate of oligosaccharide structures involved in cell-cell communication, cell-substrate interaction, adhesion, and protein targeting. ST8SIA6 belongs to a family of sialyltransferases (EC 2.4.99.8) that synthesize sialylglycoconjugates (Takashima et al., 2002 [PubMed 11980897]).

== References ==

== Further reading ==

{{refbegin | 2}} *{{cite journal |vauthors=Avril T, North SJ, Haslam SM, Willison HJ, Crocker PR |title=Probing the cis interactions of the inhibitory receptor Siglec-7 with alpha2,8-disialylated ligands on natural killer cells and other leukocytes using glycan-specific antibodies and by analysis of alpha2,8-sialyltransferase gene expression |journal=J. Leukoc. Biol. |volume=80 |issue=4 |pages=787–96 |year=2006 |pmid=16857734 |doi=10.1189/jlb.1005559 |s2cid=7578193 |doi-access= }} *{{cite journal |vauthors=Szabo R, Skropeta D, etal |title=Advancement of Sialyltransferase Inhibitors: Therapeutic Challenges and Opportunities. |journal=Med. Res. Rev. |volume=37 |pages= 210–270 |year= 2017 |issue=2 |doi= 10.1002/med.21407 |pmid=27678392|s2cid=26280291 |url=https://ro.uow.edu.au/smhpapers/4202 |url-access=subscription }} {{refend}}