| Verifiedfields | changed |
|---|---|
| Watchedfields | changed |
| Verifiedrevid | 424977941 |
| Pin | Dicyclohexyl(2′,6′-dimethoxy[1,1′-biphenyl]-2-yl)phosphane |
| Othernames | SPhos |
SPhos is a phosphine ligand derived from biphenyl. Its palladium complexes exhibit high activity for Suzuki coupling reactions involving aryl chlorides, which are unreactive with palladium complexes of most other phosphine ligands.[1] The ligand has convenient handling characteristics since it is air-stable.[2]
See also
References
- ^ Barder, T.E.; Walker, S.D.; Martinelli, J.R.; Buchwald, S. L. (2005). "New Catalysts for Suzuki-Miyaura Coupling Processes: Scope and Studies of the Effect of Ligand Structure". J. Am. Chem. Soc.. 127 (13): 4685–4696. doi:10.1021/ja042491j. PMID 15796535
- ^ Altman, R.A. & Buchwald, S.L. (2007). "Pd-Catalyzed Suzuki-Miyaura Reactions of Aryl Halides Using Bulky Biarylmonophosphine Ligands". Nature Protocols. 2 (12): 3115–3121. doi:10.1038/nprot.2007.411. PMID 18079711. S2CID 11069335