'''SEF''' may refer to:

* Sankara Eye Foundation, a non-profit that works for eradicating curable blindness in India * Serviço de Estrangeiros e Fronteiras, Portuguese Border and Alien Service * Sinfonia Educational Foundation, the philanthropic arm of the Phi Mu Alpha Sinfonia Music Fraternity * Small Enterprise Foundation, a microfinance institution operating primarily in the Limpopo province of South Africa * South Eastern Freeway, a Freeway in Australia * Special Emergency Force, A Saudi Arabian riot control and counter-terrorism force * Spectral edge frequency, a measure used in signal processing * Stadio Erinis & Filias, the Greek name for Peace and Friendship Stadium, an indoor sports arena in Athens * Straits Exchange Foundation, a semi-official organization of Taiwan that deals with the business matters with China * Supplementary eye fields, areas in the primate brain that are involved in planning and control of saccadic eye movements * Swap Execution Facility, a platform for regulated trading and clearing of swaps to be required in the United States by the Dodd-Frank bill * Swedish Elite Football * Swedish Electricians' Union, a trade union in Sweden * Seaford railway station (England), a railway station in Sussex, England

See also:

* Sef, Iran (disambiguation) * Sef Gonzales, Asian-Australian murderer

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