{{Short description|Type of Alphacoronavirus affecting swine}} {{Virusbox | image = | image_alt = | image_caption = | parent = Rhinacovirus | virus = Swine acute diarrhea syndrome coronavirus | synonyms = | synonyms_ref = | subdivision_ranks = | subdivision = }}

'''Swine acute diarrhea syndrome coronavirus''' ('''SADS-CoV''') is a coronavirus related to ''Rhinolophus bat coronavirus HKU2''. It is transmitted through the feces of horseshoe bats to pigs. Piglets less than 5 days old die with a probability of up to 90%.<ref name=":1" />

The first outbreak appeared in 2017,<ref name=":0">{{Cite journal|last1=Yang|first1=Yong-Le|last2=Yu|first2=Jia-Qi|last3=Huang|first3=Yao-Wei|date=2020-05-16|title=Swine enteric alphacoronavirus (swine acute diarrhea syndrome coronavirus): An update three years after its discovery|journal=Virus Research|volume=285|article-number=198024|doi=10.1016/j.virusres.2020.198024|issn=0168-1702|pmc=7229464|pmid=32482591}}</ref> where it caused the death of more than 24,000 piglets on 4 farms. In 2018 and 2019, the virus re-emerged in China, but there were not large-scale losses.<ref name=":0" /> This weak re-emergence is curious, and is reminiscent of how SARS emerged in 2003 and then disappeared.<ref name=":0" />

During ''in vitro'' testing, human and monkey cell lines exposed to SADS-CoV became infected, suggesting that SADS-CoV may pose a risk to human health.<ref name=":0" />

The SADS-CoV sampled from one of the first infected pig farms was found to be 95% genetically identical to one collected from horseshoe bats (''Rhinolophus''), "indicating the bat origin of the pig virus".<ref name=":1">{{Cite journal|last1=Cui|first1=Jie|last2=Li|first2=Fang|last3=Shi|first3=Zheng-Li|date=2018-12-10|title=Origin and evolution of pathogenic coronaviruses|journal=Nature Reviews. Microbiology|volume=17|issue=3|pages=181–192|doi=10.1038/s41579-018-0118-9|issn=1740-1526|pmc=7097006|pmid=30531947}}</ref>

== References == {{Reflist}}

{{Coronaviridae}} {{Taxonbar|from=Q55643348}}

Category:Alphacoronaviruses Category:Unaccepted virus taxa