S-Acylation

{{DISPLAYTITLE:''S''-Acylation}} '''''S''-Acylation''' is the process of chemically linking a molecule to another molecule via a thioester bond.<ref name="first">{{Cite journal | last1 = Forrester | first1 = M. T. | last2 = Hess | first2 = D. T. | last3 = Thompson | first3 = J. W. | last4 = Hultman | first4 = R. | last5 = Moseley | first5 = M. A. | last6 = Stamler | first6 = J. S. | last7 = Casey | first7 = P. J. | doi = 10.1194/jlr.D011106 |doi-access=free | title = Site-specific analysis of protein S-acylation by resin-assisted capture | journal = The Journal of Lipid Research | volume = 52 | issue = 2 | pages = 393–398 | year = 2010 | pmid = 21044946 | pmc =3023561 }}</ref> '''Protein ''S''-acylation''' is a sub-type of ''S''-acylation where the first of those molecules is a protein, and connected to the second through a cysteine amino acid.<ref name="first"/> A prominent type of protein ''S''-acylation is palmitoylation, which promotes lipid membrane association of the protein, for instance to the plasma membrane, Golgi apparatus, or inner nuclear membrane.<ref>{{Cite journal | last1 = Hofemeister | first1 = H. | last2 = Weber | first2 = K. | last3 = Stick | first3 = R. | title = Association of Prenylated Proteins with the Plasma Membrane and the Inner Nuclear Membrane is Mediated by the Same Membrane-targeting Motifs | journal = Molecular Biology of the Cell | volume = 11 | issue = 9 | pages = 3233–3246 | year = 2000 | pmid = 10982413 | pmc = 14988 | doi=10.1091/mbc.11.9.3233 | url = http://pubman.mpdl.mpg.de/pubman/item/escidoc:1569461/component/escidoc:1569462/1569461.pdf}}</ref>

== References == {{Reflist}}

{{DEFAULTSORT:Acylation, S-}} Category:Chemical reactions