{{Short description|American physician and researcher}} {{Orphan|date=November 2025}} {{Infobox scientist | name = Robert A. Bonomo | image = | birth_date = | birth_place = [[The Bronx|Bronx, New York, U.S.]] | fields = [[Infectious diseases]], [[microbiology]] | workplaces = [[Case Western Reserve University]]<br />Louis Stokes Veterans Affairs Medical Center | alma_mater = [[Hamilton College]] (B.A.)<br />[[Case Western Reserve University]] (M.D.) | known_for = Research on [[antimicrobial resistance]] and [[β-lactamase]]s | awards = }}
'''Robert Anthony Bonomo''' is an American physician, researcher, and academic known for his work on [[antimicrobial resistance]]. He is a Distinguished University Professor at [[Case Western Reserve University School of Medicine]], and serves as Associate Chief of Staff for Faculty Affairs and Chief Academic Officer at the Louis Stokes Cleveland [[Veterans Affairs Medical Center]].
== Early life and education == Bonomo was born in the Bronx, New York. He earned a Bachelor of Arts degree from [[Hamilton College]] in 1976 and a Doctor of Medicine (M.D.) from [[Case Western Reserve University]] in 1983. He completed residency training in internal medicine at [[University Hospitals of Cleveland]], followed by a fellowship in infectious diseases.<ref>{{cite web |title=Internal Medicine Residency Robert A. Bonomo, MD {{!}} Graduate Medical Education {{!}} University Hospitals {{!}} Cleveland, OH |url=https://www.uhhospitals.org/medical-education/medicine/internal-medicine-residency/leadership/robert-bonomo-md |website=University Hospitals}}</ref>
== Career == Bonomo began his career in internal medicine and geriatrics before focusing on infectious diseases. Since the 1990s<ref>{{cite web |title=The Cleveland VA and Case Western Reserve Collaborate to Fight Drug-Resistant Bacteria |url=https://www.ideastream.org/news/health-science/2017-03-13/the-cleveland-va-and-case-western-reserve-collaborate-to-fight-drug-resistant-bacteria |website=Ideastream Public Media |language=en |date=14 March 2017}}</ref> he has worked at the Louis Stokes Veterans Affairs Medical Center, where he has served as Chief of Medicine from 2011 to 2020, Director of the Geriatric Research, Education and Clinical Center,<ref>{{cite web |title=Cleveland GRECC - Geriatric Research Education and Clinical Center (GRECC) |url=https://www.va.gov/GRECC/Cleveland_GRECC.asp |website=Va.gov}}</ref> and Director of the Case Western Reserve University–Cleveland VAMC Center for Antimicrobial Resistance and Epidemiology (Case-VA CARES).<ref>{{cite web |title=Robert Bonomo to Lead Coordinating Center for VA SHIELD |url=https://arlg.org/robert-bonomo-to-lead-coordinating-center-for-va-shield/ |website=ARLG |date=13 May 2022}}</ref>
At Case Western Reserve University, he has held faculty appointments across multiple departments, including medicine, pharmacology, microbiology, biochemistry, and bioinformatics. He was named Distinguished University Professor in 2019.<ref>{{cite web |title=Robert Bonomo, antibiotic resistance expert, awarded Distinguished University Professorship {{!}} CWRU Newsroom {{!}} Case Western Reserve University |url=https://case.edu/news/robert-bonomo-antibiotic-resistance-expert-awarded-distinguished-university-professorship |website=Case.edu |language=en |date=23 May 2025}}</ref>
== Research == Bonomo's research centers on the molecular mechanisms of antibiotic resistance, with a focus on β-lactamases and penicillin-binding proteins in pathogens such as ''Klebsiella pneumoniae'',<ref>{{cite journal |last1=J |first1=Rojas, Laura |last2=M |first2=Weinstock, George |last3=Lorena |first3=Diaz |last4=Rafael |first4=Rios |last5=M |first5=Hanson, Blake |last6=S |first6=Brown, Joseph |last7=Purva |first7=Vats |last8=S |first8=Phillips, Daniel |last9=Hoan |first9=Nguyen |last10=M |first10=Hujer, Kristine |last11=Adriana |first11=Correa |last12=D |first12=Adams, Mark |last13=Federico |first13=Perez |last14=Erica |first14=Sodergren |last15=Apurva |first15=Narechania |last16=J |first16=Planet, Paul |last17=V |first17=Villegas, Maria |last18=A |first18=Bonomo, Robert |last19=A |first19=Arias, Cesar |title=An Analysis of the Epidemic of Klebsiella pneumoniae Carbapenemase-Producing K. pneumoniae: Convergence of Two Evolutionary Mechanisms Creates the "Perfect Storm" |journal=The Journal of Infectious Diseases |date=1 January 2018 |volume=217 |issue=1 |doi=10.1093/infdi |doi-broken-date=3 November 2025 |url=https://academic.oup.com/jid/article/217/1/82/4259398 |language=en |issn=0022-1899}}</ref> ''Acinetobacter baumannii'',<ref>{{cite journal |last1=Mack |first1=Andrew R. |last2=Hujer |first2=Andrea M. |last3=Mojica |first3=Maria F. |last4=Taracila |first4=Magdalena A. |last5=Feldgarden |first5=Michael |last6=Haft |first6=Daniel H. |last7=Klimke |first7=William |last8=Prasad |first8=Arjun B. |last9=Bonomo |first9=Robert A. |title=β-Lactamase diversity in Acinetobacter baumannii |journal=Antimicrobial Agents and Chemotherapy |date=5 March 2025 |volume=69 |issue=3 |pages=e0078424 |doi=10.1128/aac.00784-24 |pmid=39927782 |pmc=11881555 |issn=1098-6596}}</ref> and ''Pseudomonas aeruginosa''. His laboratory has contributed to structural and functional studies of β-lactamase enzymes, the development of β-lactamase inhibitors,<ref>{{cite journal |last1=Bonomo |first1=Robert A. |title=β-Lactamases: A Focus on Current Challenges |journal=Cold Spring Harbor Perspectives in Medicine |date=3 January 2017 |volume=7 |issue=1 |article-number=a025239 |doi=10.1101/cshperspect.a025239 |pmid=27742735 |pmc=5204326 |issn=2157-1422}}</ref><ref>{{cite web |title=A Themed Issue in Honor of Professor Robert A. Bonomo—Outstanding Contributions in the Fields of ß-Lactamase Inhibitors |url=https://www.mdpi.com/journal/antibiotics/special_issues/Q3K6I3A6UL |publisher=MDPI}}</ref> and molecular diagnostics for multidrug-resistant organisms.
He has authored more than 700 peer-reviewed scientific papers and is listed as a co-inventor on several patents for novel antimicrobial agents.
== Honors and awards == * 2024 - Maxwell Finland Lecture, [[Infectious Diseases Society of America]]<ref>{{cite web |title=Maxwell Finland Lecture |url=https://www.idsociety.org/about-us/lecturers/maxwell-finland-lecture/ |website=Idsociety.org |language=en}}</ref> * 2020 - Wolcott Award for Excellence in Clinical Care Leadership, VA Healthcare System<ref>{{cite web |title=2020 Wolcott Award Goes to Robert A. Bonomo, MD |url=https://arlg.org/2020-wolcott-award-goes-to-robert-a-bonomo-md/ |website=ARLG |date=17 January 2020}}</ref> * 2019-2023 - [[Highly Cited Researchers|Clarivate Highly Cited Researcher]]<ref>{{cite web |title=Editorial Board Members from Antibiotics Featured in the 2023 Highly Cited Researchers List Published by Clarivate |url=https://www.mdpi.com/about/announcements/7132 |publisher=Mdpi.com}}</ref> * 2017 - [[William S. Middleton Award]], [[Veterans Health Administration]]<ref>{{cite web |title=William S. Middleton Award |url=https://www.research.va.gov/isrm/blrd/middleton.cfm#2017 |website=Va.gov |language=en |date=17 June 2025}}</ref> * 2016 - Excellence in Clinical Microbiology and Infectious Diseases Award, [[European Society of Clinical Microbiology and Infectious Diseases]]<ref>{{cite web |title=Prof. Robert A. Bonomo received the ESCMID Award |url=https://biotechinfo.fr/article/prof-robert-a-bonomo-received-the-escmid-award/ |website=Biotech.info |language=fr-FR}}</ref> * 2011 - Fellow, [[American Academy of Microbiology]]<ref>{{cite web |title=ASM Directory Search Results |url=https://myasm.asm.org/eweb/DynamicPage.aspx?Site=ASM&WebKey=abbcf18d-3f11-46a6-95d7-956eed2a9cf3&type=acfellows&FromSearchControl=Yes |website=ASM}}</ref> * Fellow, [[Infectious Diseases Society of America]] * Fellow, [[European Society of Clinical Microbiology and Infectious Diseases]]<ref>{{cite web |title=ESCMID Fellows |url=https://www.escmid.org/about-us/network/escmid-fellows/ |website=ESCMID |language=en}}</ref>
== References == {{reflist}} {{authority control}}
{{DEFAULTSORT:Bonomo, Robert A.}} [[Category:Living people]] [[Category:American medical doctors]] [[Category:Case Western Reserve University faculty]] [[Category:American microbiologists]] [[Category:Hamilton College (New York) alumni]] [[Category:Case Western Reserve University alumni]] [[Category:Year of birth missing (living people)]]