{{Short description|Protein-coding gene in the species Homo sapiens}} {{Infobox_gene}} '''RNA-binding protein Raly''' is a protein that in humans is encoded by the ''RALY'' gene.<ref name="pmid10500250">{{cite journal | vauthors = Khrebtukova I, Kuklin A, Woychik RP, Michaud EJ | title = Alternative processing of the human and mouse raly genes(1) | journal = Biochim Biophys Acta | volume = 1447 | issue = 1 | pages = 107–12 |date=Nov 1999 | pmid = 10500250 | doi = 10.1016/s0167-4781(99)00126-8| url = https://zenodo.org/record/1259893 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: RALY RNA binding protein, autoantigenic (hnRNP-associated with lethal yellow homolog (mouse))| url = https://www.ncbi.nlm.nih.gov/gene?Db=gene&Cmd=ShowDetailView&TermToSearch=22913}}</ref>

In infectious mononucleosis, anti-EBNA-1 antibodies are produced which cross-react with multiple normal human proteins. The cross-reactivity is due to anti-gly/ala antibodies that cross-react with host proteins containing configurations like those in the EBNA-1 repeat. One such antigen is RALY which is a member of the heterogeneous nuclear ribonucleoprotein gene family.<ref name="entrez" />

==References== {{reflist}}

==Further reading== {{refbegin | 2}} *{{cite journal |vauthors=Olsen JV, Blagoev B, Gnad F, etal |title=Global, in vivo, and site-specific phosphorylation dynamics in signaling networks |journal=Cell |volume=127 |issue= 3 |pages= 635–48 |year= 2006 |pmid= 17081983 |doi= 10.1016/j.cell.2006.09.026 |s2cid=7827573 |doi-access=free }} *{{cite journal | vauthors=Beranova-Giorgianni S, Zhao Y, Desiderio DM, Giorgianni F |title=Phosphoproteomic analysis of the human pituitary |journal=Pituitary |volume=9 |issue= 2 |pages= 109–20 |year= 2006|pmid= 16807684 |doi= 10.1007/s11102-006-8916-x |s2cid=10789246 }} *{{cite journal |vauthors=Lim J, Hao T, Shaw C, etal |title=A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration |journal=Cell |volume=125 |issue= 4 |pages= 801–14 |year= 2006 |pmid= 16713569 |doi= 10.1016/j.cell.2006.03.032 |s2cid=13709685 |doi-access=free }} *{{cite journal |vauthors=Gerhard DS, Wagner L, Feingold EA, etal |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC) |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928 }} *{{cite journal |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 |bibcode=2002PNAS...9916899M |doi-access=free }} *{{cite journal |vauthors=Jurica MS, Licklider LJ, Gygi SR, etal |title=Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis |journal=RNA |volume=8 |issue= 4 |pages= 426–39 |year= 2002 |pmid= 11991638 |doi=10.1017/S1355838202021088 | pmc=1370266 }} *{{cite journal |vauthors=Deloukas P, Matthews LH, Ashurst J, etal |title=The DNA sequence and comparative analysis of human chromosome 20 |journal=Nature |volume=414 |issue= 6866 |pages= 865–71 |year= 2002 |pmid= 11780052 |doi= 10.1038/414865a |bibcode=2001Natur.414..865D |doi-access= free }} *{{cite journal | vauthors=Rhodes GH, Valbracht JR, Nguyen MD, Vaughan JH |title=The p542 gene encodes an autoantigen that cross-reacts with EBNA-1 of the Epstein Barr virus and which may be a heterogeneous nuclear ribonucleoprotein |journal=J. Autoimmun. |volume=10 |issue= 5 |pages= 447–54 |year= 1997 |pmid= 9376072 |doi= 10.1006/jaut.1997.9996 }} *{{cite journal |vauthors=Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, etal |title=Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library |journal=Gene |volume=200 |issue= 1–2 |pages= 149–56 |year= 1997 |pmid= 9373149 |doi=10.1016/S0378-1119(97)00411-3 }} *{{cite journal | vauthors=Maruyama K, Sugano S |title=Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides |journal=Gene |volume=138 |issue= 1–2 |pages= 171–4 |year= 1994 |pmid= 8125298 |doi=10.1016/0378-1119(94)90802-8 }} *{{cite journal |vauthors=Vaughan JH, Valbracht JR, Nguyen MD, etal |title=Epstein-Barr virus-induced autoimmune responses. I. Immunoglobulin M autoantibodies to proteins mimicking and not mimicking Epstein-Barr virus nuclear antigen-1 |journal=J. Clin. Invest. |volume=95 |issue= 3 |pages= 1306–15 |year= 1995 |pmid= 7533788 |doi=10.1172/JCI117781 | pmc=441470 }} {{refend}} {{PDB Gallery|geneid=22913}}

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