{{Short description|Stabilized form of laminin}} {{use dmy dates|date=March 2026}} '''Polylaminin''' or '''polyLM''', is a stabilized form of laminin, a family of natural proteins, which is being studied for use in treating spinal cord injuries in animals and humans.<ref>{{cite web |url=https://www1.folha.uol.com.br/internacional/en/scienceandhealth/2025/09/groundbreaking-brazilian-drug-considered-capable-of-reversing-spinal-cord-injury-presented-in-sao-paulo.shtml |title=Groundbreaking Brazilian Drug, Considered Capable of Reversing Spinal Cord Injury, Presented in São Paulo|date=2025-11-09|access-date=2026-03-02|first1=Jairo|last1=Marques|first2=Patrícia|last2=Pasquini|publisher=Folha de S.Paulo}}</ref><ref>{{cite medRxiv |first1=Karla|last1=Menezes|first2=Marco Aurelio B.|last2=Lima|first3=Denise R.|last3=Xerez|display-authors=2 |name-list-style= |date=2024-02-21 |title=Return of Voluntary Motor Contraction After Complete Spinal Cord Injury: A Pilot Human Study on Polylaminin |at= |medrxiv=10.1101/2024.02.19.24301010v1 }}</ref><ref>{{cite web |url=https://ensaiosclinicos.gov.br/news/331 |title=Brazilian scientists use placenta protein to restore some movement in dogs and humans with spinal cord injuries}}</ref> In early human trials, a patient with a fractured neck vertebra after a car accident had a full recovery after a year, and a chronic quadriplegic patient regained arm movement.<ref>{{cite web |url=https://valorinternational.globo.com/business/news/2025/09/10/cristalia-drug-offers-hope-for-quadriplegia-patients.ghtml |title=Cristália drug offers hope for quadriplegia patients|date=2025-09-11|first=Ana Luiza|last=de Carvalho|access-date=2026-03-02|publisher=Valor International}}</ref><ref name="Talk">{{cite web | url=https://www.youtube.com/watch?v=quYlC-uBsn0 | title=The case of polylaminin in the treatment of spinal cord injuries | publisher=YouTube | author=National Cancer Institute | date=2023-04-04 | accessdate=2025-10-03}}</ref><ref name="Podcast">{{cite web | url=https://www.youtube.com/watch?v=QcvWaG4UxAs | title=Polylaminin: The Brazilian discovery that could transform the treatment of spinal cord injuries | publisher=YouTube | author=National Cancer Institute | date=2025-10-30 | accessdate=2025-10-03}}</ref> The Brazilian Academy of Neurology, Brazilian Academy of Sciences, and the Brazilian Society for the Progress of Science advise caution before clinical tests are completed.<ref>{{Cite web |title=Neurologists Warn of Lack of Evidence Regarding Polylaminin's Action in Spinal Cord Injury |url=https://www1.folha.uol.com.br/internacional/en/scienceandhealth/2026/02/neurologists-warn-of-lack-of-evidence-regarding-polylaminins-action-in-spinal-cord-injury.shtml |access-date=2026-03-01 |date=2026-02-24|first=Cláudia|last=Collucci|publisher=Folha de S.Paulo}}</ref>
== References == {{reflist}}
Category:Laminins
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