{{Short description|Croatian pharmaceutical company}} {{About|the Croatian company|the river in Bosnia and Herzegovina|Pliva (river)|the waterfall in Bosnia and Herzegovina|Pliva Waterfall|the Beninese actor, stage director and playwright|José Pliva}} {{Infobox company | name = Pliva d.o.o. | logo = PLIVA Logo.svg | type = Subsidiary | industry = Pharmaceutical industry | parent = Teva Pharmaceuticals | founded = {{Start date and age|1921}} | location = Zagreb, Croatia | key_people = Mihael Furjan <small>(CEO)</small> | num_employees = 1,700 | products = Generic drugs | revenue = $1.174 billion <small>(2005)</small> | net_income = $0.336 billion <small>(2005)</small> | website = {{url|http://www.pliva.com/}} | footnotes = <ref name=profile>{{cite web | url=http://www.pliva.com/press/company-profile | title=Company Profile | publisher=Pliva}}</ref> }} thumb|upright|right|240 px|Pliva headquarters in Zagreb thumb|Azithromycin, also known as Sumamed, is one of the world's best-selling antibiotics. '''Pliva''' d.o.o. is a pharmaceutical company based in Zagreb, Croatia that primarily manufactures and sells generic drugs. It is a subsidiary of Teva Pharmaceuticals.
Pliva is one of the world's largest producers of generic Adderall.{{citation needed|date=May 2020}}
==History== In 1918 Gustav Janeček founded the wholesale drug company Isis (today Medika).<ref>{{cite web | title = JANEČEK, Gustav | url = https://hbl.lzmk.hr/clanak/125 | website = Hrvatski biografski leksikon | language = hr | access-date = 27 September 2025}}</ref> In 1921 he co-founded the pharmaceutical factory Kaštel d.d. in Karlovac as a joint venture with Isis and Budapest-based Chinoin, and served as the company's first president of the board. The company kept its name after moving production to Zagreb in 1927. It was only in 1941 that it was renamed PLIVA as an acronym for the State Institute for Production of Medicines and Vaccines.<ref>{{cite news | title = Preteča Plive osnovana je u starom dvorcu u Karlovcu 1921. | work = Večernji list | date = 1 October 2018 | language = hr | url = https://www.vecernji.hr/biznis/preteca-plive-osnovana-je-u-starom-dvorcu-u-karlovcu-1921-1273400 | access-date = 27 September 2025 | author = Snježana Bičak}}</ref><ref>{{cite journal | last = Inić | first = S. | author2 = V. Flegar | title = Adolf Thierry and the first pharmaceutical factory in Croatia | journal = Pharmazie | year = 2021 | volume = 76 | issue = 2 | pages = 81–86 | language = de | url = https://www.ingentaconnect.com/contentone/govi/pharmaz/2021/00000076/f0020002/art00012 | access-date = 27 September 2025}}</ref><ref>{{cite web | title = PLIVA d.d. | website = International Directory of Company Histories via Encyclopedia.com | language = en | url = https://www.encyclopedia.com/books/politics-and-business-magazines/pliva-dd | access-date = 27 September 2025}}</ref><ref>{{cite news | title = Dionice tvrtke Kaštel, iz koje je kasnije nastala Pliva, oduzete su njegovom djedu krajem 2. svjetskog rata... | work = Jutarnji list | date = 11 May 2017 | language = hr | url = https://www.jutarnji.hr/life/zivotne-price/dionice-tvrtke-kastel-iz-koje-je-kasnije-nastala-pliva-oduzete-su-njegovom-djedu-krajem-2-svjetskog-rata-a-hrvatska-mu-sada-mora-platiti-odstetu-6038684 | access-date = 27 September 2025}}</ref>
A team of Pliva's researchers, Gabrijela Kobrehel, Gorjana Radobolja-Lazarevski and Zrinka Tamburašev led by Dr. Slobodan Đokić, discovered azithromycin in 1980.<ref>{{Cite journal |last=Mutak |first=Stjepan |date=2007 |title=Azalides from Azithromycin to New Azalide Derivatives |url=https://www.nature.com/articles/ja200710 |journal=The Journal of Antibiotics |language=en |volume=60 |issue=2 |pages=85–122 |doi=10.1038/ja.2007.10 |issn=0021-8820|doi-access=free }}</ref>
In June 2002, the company acquired Sidmak for $152.9 million.<ref>{{cite press release | url=http://www.pliva.com/press/news/article/587/PLIVA-announces-acquisition-of-US-based-Sidmak.html | title=PLIVA announces acquisition of US-based Sidmak | publisher=Pliva | date=June 11, 2002}}</ref>
Also in June 2002, Zeljko Peric, the chief financial officer of the company, resigned.<ref>{{cite press release | url=http://pliva.com/press/news/article/548/PLIVA-announces-management-changes.html | title=PLIVA announces management changes | publisher=Pliva | date=June 27, 2002}}</ref>
In May 2004, the company received approval from the Food and Drug Administration to sell trospium chloride.<ref>{{cite press release | url=http://www.pliva.com/press/news/article/610/PLIVA-Announces-FDA-Approval-of-SANCTURA.html | title=PLIVA Announces FDA Approval of SANCTURA | publisher=Pliva | date=May 31, 2004}}</ref>
In June 2005, the company received approval to sell a generic version of erythropoietin in Croatia.<ref>{{cite press release | url=http://www.pliva.com/press/news/article/735/PLIVA-Registers-generic-EPO-in-Croatia.html | title=PLIVA Registers generic EPO in Croatia | publisher=Pliva | date=June 21, 2005}}</ref>
In November 2005, the company received approval from the Food and Drug Administration to sell a generic version of Azithromycin,<ref>{{cite press release | url=http://www.pliva.com/press/news/article/760/PLIVA-Announces-Approval-for-Azithromycin-Tablets.html | title=PLIVA Announces Approval for Azithromycin Tablets | publisher=Pliva | date=November 15, 2005}}</ref> Citalopram,<ref>{{cite press release | url=http://www.pliva.com/press/news/article/754/PLIVA-Announces-Approval-for-Citalopram-Hydrobromide-Tablets.html | title=PLIVA Announces Approval for Citalopram Hydrobromide Tablets | publisher=Pliva | date=November 3, 2005}}</ref> and Ondansetron.<ref>{{cite press release | url=http://www.pliva.com/press/news/article/761/PLIVA-Announces-Approval-for-Ondansetron-Hydrochloride-ODT.html | title=PLIVA Announces Approval for Ondansetron Hydrochloride ODT | publisher=Pliva | date=November 21, 2005}}</ref>
In October 2006, Barr Pharmaceuticals acquired Pliva.<ref>{{cite press release | url=http://www.pliva.com/press/news/article/825/Barr-Acquires-PLIVA-dd.html | title=Barr Acquires PLIVA d.d. | publisher=Pliva | date=October 12, 2006}}</ref>
On December 23, 2008, Barr Pharmaceuticals was acquired by Teva Pharmaceuticals and the company became part of Teva Active Pharmaceutical Ingredients (TAPI).<ref>{{cite press release | url=http://www.pliva.com/press/news/article/888/TEVA-COMPLETES-ACQUISITION-OF-BARR.html | title=TEVA COMPLETES ACQUISITION OF BARR | publisher=Pliva | date=December 23, 2008}}</ref>
==References== {{Reflist|1}}
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Category:1921 establishments in Croatia Category:Manufacturing companies based in Zagreb Category:Croatian brands Category:Pharmaceutical companies established in 1921 Category:Pharmaceutical companies of Croatia Category:2006 mergers and acquisitions