{{Chembox | Verifiedfields = changed | Watchedfields = changed | verifiedrevid = 321800934 | ImageFile = Pendetide structure.svg | ImageClass = skin-invert-image | ImageSize = | IUPACName = ''N<sup>6</sup>''-[''N''-[2-<nowiki>[[</nowiki>2-[Bis(carboxymethyl)amino]ethyl](carboxymethyl)amino]ethyl]-''N''-(carboxymethyl)glycyl]-''N<sup>2</sup>''-(''N''-glycyl-<small>L</small>-tyrosyl)-<small>L</small>-lysine | OtherNames = | Section1 = {{Chembox Identifiers | CASNo_Ref = {{cascite|correct|??}} | CASNo = 148805-91-8 | UNII_Ref = {{fdacite|correct|FDA}} | UNII = 60C8D1C9UJ | PubChem = 66648912
| ChemSpiderID_Ref = {{chemspidercite|changed|chemspider}} | ChemSpiderID = 16737038 | SMILES = c1cc(ccc1CC(C(=O)NC(CCCCNC(=O)CN(CCN(CCN(CC(=O)O)CC(=O)O)CC(=O)O)CC(=O)O)C(=O)O)NC(=O)CN)O | InChI = 1/C31H47N7O14/c32-14-24(40)34-23(13-20-4-6-21(39)7-5-20)30(50)35-22(31(51)52)3-1-2-8-33-25(41)15-37(17-27(44)45)11-9-36(16-26(42)43)10-12-38(18-28(46)47)19-29(48)49/h4-7,22-23,39H,1-3,8-19,32H2,(H,33,41)(H,34,40)(H,35,50)(H,42,43)(H,44,45)(H,46,47)(H,48,49)(H,51,52)/t22-,23-/m0/s1 | InChIKey = ZMEWRPBAQVSBBB-GOTSBHOMBD | StdInChI_Ref = {{stdinchicite|changed|chemspider}} | StdInChI = 1S/C31H47N7O14/c32-14-24(40)34-23(13-20-4-6-21(39)7-5-20)30(50)35-22(31(51)52)3-1-2-8-33-25(41)15-37(17-27(44)45)11-9-36(16-26(42)43)10-12-38(18-28(46)47)19-29(48)49/h4-7,22-23,39H,1-3,8-19,32H2,(H,33,41)(H,34,40)(H,35,50)(H,42,43)(H,44,45)(H,46,47)(H,48,49)(H,51,52)/t22-,23-/m0/s1 | StdInChIKey_Ref = {{stdinchicite|changed|chemspider}} | StdInChIKey = ZMEWRPBAQVSBBB-GOTSBHOMSA-N}} | Section2 = {{Chembox Properties | Formula = C<sub>31</sub>H<sub>47</sub>N<sub>7</sub>O<sub>14</sub> | MolarMass = 741.318 g/mol | Appearance = | Density = | MeltingPt = | BoilingPt = | Solubility = }} }} '''Pendetide''' ('''GYK-DTPA''') is a chelating agent. It consists of pentetic acid (DTPA) linked to the tripeptide glycine (G) – <small>L</small>-tyrosine (Y) – <small>L</small>-lysine (K).<ref>[https://web.archive.org/web/20040627024748/http://whqlibdoc.who.int/inn/proposed_lists/prop_INN_list67.pdf WHO Drug Information]</ref>
==Use== The following monoclonal antibodies are linked to pendetide to chelate a radionuclide, indium-111. The antibodies selectively bind to certain tumour cells, and the radioactivity is then used for imaging of the tumours. * Indium (<sup>111</sup>In) capromab pendetide (prostate cancer) * Indium (<sup>111</sup>In) satumomab pendetide (other cancer types)
==References== {{reflist}}
Category:Chelating agents Category:Chelating agents used as drugs Category:Carboxylic acids Category:Peptides
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