Patricia Janak

{{Short description|American neuroscientist (born 1965)}} {{Infobox scientist | name = Patricia Janak | image = Patricia Janak au Loyola.png | image_size = | caption = | birth_date = {{birth year and age|1965}} | birth_place = United States | field = Neuroscience Behavioral Neuroscience Neurobiology Psychology Neurology | workplaces = Johns Hopkins University | alma_mater = Rutgers University (B.A., 1986) University of California, Berkeley (M.A., 1990) University of California, Berkeley (Ph.D., 1993) Wake Forest School of Medicine | doctoral_advisor = | doctoral_students = Kay Tye | known_for = Addiction research | prizes = Bloomberg Distinguished Professorships (2014) Member, Society for Neuroscience Member, Research Society on Alcoholism }} '''Patricia Janak''' is a Bloomberg Distinguished Professor at Johns Hopkins University who studies the biological basis of behavior through associative learning.<ref>{{cite web|title=Bloomberg Distinguished Professorships|url=http://web.jhu.edu/administration/provost/BDP}}</ref> Janak applies this research to pathological behaviors, such as addiction and posttraumatic stress disorder, to improve understanding of how stimuli affect relapse and responses.<ref name="hub.jhu.edu">Brooks, Kelly [http://hub.jhu.edu/2014/06/11/bloomberg-professors-morgan-janak-sutcliffe "Johns Hopkins appoints three new Bloomberg Distinguished Professors"], ''JHU Hub'', Baltimore, 11 June 2014. Retrieved on 11 May 2015.</ref>

==Biography== Janak was born in 1965 to Peter Janak and Bonnie Stringfellow.<ref>{{cite web|title=Genealogy: Patricia Helene Janak|url=http://www.genealogy.com/ftm/t/o/e/April-L-Toeppe-Oh/WEBSITE-0001/UHP-0221.html}}</ref> Janak began training in biological science and behavioral science as an undergraduate double major in Biology and Psychology at Rutgers University. She earned master's and doctoral degrees in Psychology from the University of California, Berkeley, the latter under Joe L. Martinez Jr.<ref>{{cite web|title=Neurotree: Joe L Martinez|url= http://neurotree.org/neurotree/peopleinfo.php?pid=6656}}</ref> While completing her doctoral work, she also held adjunct faculty positions at the Wright Institute, Santa Clara University, and California State University, East Bay. She completed post-doctoral work at the National Institute on Drug Abuse, a branch of the National Institutes of Health, and in physiology and pharmacology at the Wake Forest School of Medicine under the guidance of Donald J Woodward,<ref>{{cite web|title=Neurotree: Donald J Woodward|url= http://neurotree.org/neurotree/peopleinfo.php?pid=965}}</ref> who pioneered the development of "awake-animal behavioral and multi-neuronal recording techniques" in the 1990s.<ref>{{cite web|title= Professor Donald J. Woodward Visiting the Institute of Psychology|url=http://english.psych.cas.cn/ns/icn/200912/t20091224_49516.html}}</ref> Janak joined the faculty of the University of California, San Francisco as an assistant professor in the Ernest Gallo Clinic and Research Center in 1999.<ref name="neuroscience.ucsf.edu">{{cite web|title=Behavioral Neuroscience of Addiction and Reinforcement|url=http://www.neuroscience.ucsf.edu/neurograd/faculty/janak.html|url-status=dead|archive-url=https://web.archive.org/web/20150404214706/http://www.neuroscience.ucsf.edu/neurograd/faculty/janak.html|archive-date=2015-04-04}}</ref> She was named the Howard J. Weinberger Endowed Chair in Addiction Research at USCF in 2011.<ref>{{cite web|title=Endowed Chairs and Professorships in Neurology|url=http://neurology2.ucsf.edu/brain/faculty/professorships/}}{{dead link|date=March 2018 |bot=InternetArchiveBot |fix-attempted=yes }}</ref>

In June 2014, Janak was named a Bloomberg Distinguished Professor at Johns Hopkins University for her accomplishments as an interdisciplinary researcher and excellence in teaching.<ref>{{cite web|title=Michael R. Bloomberg commits $350 million to Johns Hopkins for transformational academic initiative|url= http://hub.jhu.edu/2013/01/26/bloomberg-gift|date= 2013-01-26}}</ref><ref name=anderson>Anderson, Nick. [https://www.washingtonpost.com/local/education/bloomberg-pledges-350-million-to-johns-hopkins-university/2013/01/26/9c0e1a5a-67d6-11e2-93e1-475791032daf_story.html " Bloomberg pledges $350 million to Johns Hopkins University "], ''The Washington Post'', Washington, D.C., 23 January 2013. Retrieved on 12 March 2015.</ref> The Bloomberg Distinguished Professorship program was established in 2013 by a gift from Michael Bloomberg.<ref>Barbaro, Michael. [https://www.nytimes.com/2013/01/27/nyregion/at-1-1-billion-bloomberg-is-top-university-donor-in-us.html "$1.1 Billion in Thanks From Bloomberg to Johns Hopkins"], ''The New York Times'', New York, 26 January 2013. Retrieved on 1 March 2015.</ref><ref>{{cite web|title=Michael R. Bloomberg Commits $350 Million to Johns Hopkins for Transformational Academic Initiative 2013|url= http://releases.jhu.edu/2013/01/26/michael-r-bloomberg-commits-350-million-to-johns-hopkins/}}</ref> Janak holds joint appointments in the Johns Hopkins University School of Arts and Sciences' Department of Psychological and Brain Sciences<ref>{{cite web|title=Department of Psychological and Brain Sciences: Patricia Janak, Ph.D.|url=http://pbs.jhu.edu/research/janak/facultyinfo/|access-date=2015-05-13|archive-url=https://web.archive.org/web/20150719023538/http://pbs.jhu.edu/research/janak/facultyinfo/|archive-date=2015-07-19|url-status=dead}}</ref> and the Johns Hopkins School of Medicine's Solomon H. Snyder Department of Neuroscience.<ref>{{cite web|title=Department of Neuroscience: Patricia Janak, Ph.D.|url=http://neuroscience.jhu.edu/resources/directory/faculty/patricia-janak/}}</ref>

==Research== Janak is an investigator in the field of the biological basis of behavior working on associative learning.<ref name="neuroscience.ucsf.edu"/><ref>{{cite web|title= Janak Lab|url= http://pbs.jhu.edu/research/janak/|access-date= 2015-05-13|archive-date= 2015-07-18|archive-url= https://web.archive.org/web/20150718024247/http://pbs.jhu.edu/research/janak|url-status= dead}}</ref> Her work empirically bridges formal learning theories and systems neuroscience in the mammalian brain. Using models based on theories of learning in combination with laboratory experiments,<ref>Janak, Patricia H [http://www.nature.com/neuro/journal/v16/n7/fig_tab/nn.3413_F2.html "Dopamine neuron stimulation drives new learning"], "PLOS ONE", San Francisco, 26 May 2013. Retrieved 13 May 2015.</ref> Janak investigates associative processes and the hierarchical organization of relational and representational neural encoding.<ref>Janak, Patricia H [http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0094771 "Positive Reinforcement Mediated by Midbrain Dopamine Neurons Requires D1 and D2 Receptor Activation in the Nucleus Accumbens"], "Nature (journal)", New York, 14 April 2014. Retrieved 13 May 2015.</ref> Electrophysiological recordings from neurons in defined circuits are done using pharmacological and neurophysiological tools to manipulate circuit properties.<ref>Janak, Patricia H [http://www.nature.com/neuro/journal/v16/n7/full/nn.3413.html "A causal link between prediction errors, dopamine neurons and learning"], "Nature (journal)", New York, 26 May 2013. Retrieved 13 May 2015.</ref><ref>{{cite web|title=WILS Coffee Talk with Dr. Patricia Janak|url=http://ucsf.orgsync.com/org/wils/Events|access-date=2015-05-13|archive-date=2015-08-16|archive-url=https://web.archive.org/web/20150816235138/http://ucsf.orgsync.com/org/wils/Events|url-status=dead}}</ref> She has a demonstrated interest in a translational<ref>Janak, Patricia [https://www.scopus.com/record/display.url?eid=2-s2.0-84890417075&origin=resultslist&sort=plf-f&sot=autdocs&sdt=autdocs&sl=17&s=AU-ID%287003824037%29&relpos=4&relpos=4&citeCnt=0&searchTerm= "Nucleus accumbens plasticity underlies multifaceted behavioral changes associated with addiction"], "Biological Psychiatry", Dallas, 15 January 2014. Retrieved 13 May 2015.</ref><ref>Janak, Patricia [https://www.scopus.com/record/display.url?eid=2-s2.0-84896822332&origin=resultslist&sort=plf-f&sot=autdocs&sdt=autdocs&sl=17&s=AU-ID%287003824037%29&relpos=5&relpos=5&citeCnt=1&searchTerm= "Pavlovian-conditioned alcohol-seeking behavior in rats is invigorated by the interaction between discrete and contextual alcohol cues: Implications for relapse"], "Brain and Behavior", New York, 1 March 2014. Retrieved on 13 May 2015.</ref> approach to clinical conditions.<ref>Rivas, Anthony [http://www.medicaldaily.com/drug-could-help-alcoholics-forget-theyre-addicted-blocking-their-memories-247223 "Drug Could Help Alcoholics Forget They're Addicted By Blocking Their Memories"], "Medical Daily", New York, 27 June 2013. Retrieved on 10 May 2015.</ref><ref>Shen, Helen and Nature magazine [http://www.scientificamerican.com/article/boozy-memory-blocking-reduces-risk-of-relapse-among-alcohol-abusers/ "Boozy Memory Blocking Reduces Risk of Relapse among Alcohol Abusers"], "Scientific American", New York, 24 June 2013. Retrieved on 13 May 2015.</ref> The fundamental aspects of learning and memory in the models she studies are basic to a broad range of human behaviors and can serve as a guide to intervention and therapies when capacities fail to develop normally or break down through disease.<ref>Janak, Patricia H [https://www.scopus.com/record/display.url?eid=2-s2.0-84923163629&origin=resultslist&sort=plf-f&sot=autdocs&sdt=autdocs&sl=17&s=AU-ID%287003824037%29&relpos=0&relpos=0&citeCnt=1&searchTerm= From circuits to behaviour in the amygdala"], "Nature (journal)", New York, 15 January 2015. Retrieved 13 May 2015.</ref><ref>Janak, Patricia and Virginia Long [http://www.sciencedirect.com/science/article/pii/B9780124059412000134 "Neurobiology of Alcohol Dependence: Chapter 13 - Extrasynaptic GABAA Receptors and Alcohol"], "Elsevier", London, 1 February 2014. Retrieved 8 May 2015.</ref> Her most cited article,<ref name="Author: Janak, Patricia H.">Scopus [https://www.scopus.com/authid/detail.url?authorId=7003824037 "Author: Janak, Patricia H."], ''Scopus'', Amsterdam, 13 May 2015. Retrieved on 13 May 2015.</ref> titled, "A causal link between prediction errors, dopamine neurons and learning," was published in 2013 in ''Nature Neuroscience''.<ref>Steinberg, E.E., Keiflin, R., Boivin, J.R., Witten, I.B., Deisseroth, K., and Janak, P.H.[https://www.scopus.com/record/display.url?eid=2-s2.0-84891681994&origin=resultslist&sort=plf-f&sot=autdocs&sdt=autdocs&sl=17&s=AU-ID%287003824037%29&relpos=6&relpos=6&citeCnt=87&searchTerm= "A causal link between prediction errors, dopamine neurons and learning,"]''Nature Neuroscience'', New York, 1 July 2013. Retrieved 14 August 2015.</ref>

Janak has 150 total publications, including 11 review papers, with more than 11,000 total citations and an H index of 59.<ref name="Author: Janak, Patricia H."/> She has been a member of the Society for Neuroscience since 1987 and the Research Society on Alcoholism since 1994.<ref>{{cite web|title=Society for Neuroscience Member Directory|url=http://www.sfn.org/member-center/member-directory/member-detail?m=MDAwMTA2NzY1}}</ref> Janak has taught both undergraduate and graduate courses on a variety of topics including psychology, data analysis, behavioral neuroscience, and drug addiction. At Johns Hopkins, Janak is teaching graduate psychology and neuroscience courses and an undergraduate course on learning and memory,<ref name="hub.jhu.edu"/> and actively participating in the interdisciplinary Science of Learning Institute.<ref>{{cite web|title=Science of Learning Institute Steering Committee|url=http://scienceoflearning.jhu.edu/|access-date=2015-05-13|archive-date=2015-04-05|archive-url=https://web.archive.org/web/20150405130101/http://scienceoflearning.jhu.edu/|url-status=dead}}</ref><ref>{{cite web|title=New Bloomberg Professors Taking on Global Challenges|url= http://krieger.jhu.edu/magazine/2014/10/new-bloomberg-professors-taking-on-global-challenges/|date= 2014-10-28}}</ref>

In 2023 Janak was awarded Fellow of the American Association for the Advancement of Science.<ref>{{Cite web |title=2023 AAAS Fellows {{!}} American Association for the Advancement of Science (AAAS) |url=https://www.aaas.org/fellows/2023-fellows |access-date=2025-03-06 |website=www.aaas.org |language=en}}</ref>

== Publications == Janak has more than 15,000 citations in Google Scholar and an h-index of 68.<ref>{{Cite web|title=patricia janak|url=https://scholar.google.com/citations?user=FMeKJUoAAAAJ&hl=en|access-date=2021-05-18|website=scholar.google.com}}</ref>

* [https://pubmed.ncbi.nlm.nih.gov/?term=Janak+PH&cauthor_id=25592533 Pubmed citations] * [https://scholar.google.com/citations?user=FMeKJUoAAAAJ&hl=en Google Scholar citations]

'''Selected Publications'''

* 2015 with KM Tye, ''From circuits to behaviour in the amygdala'', in: ''Nature''. Vol. 517, nº 7534; 284–292. * 2013 with EE Steinberg, R Keiflin, JR Boivin, IB Witten, K Deisseroth, ''A causal link between prediction errors, dopamine neurons and learning'', in: ''Nature Neuroscience''. Vol. 16, nº 7; 966–973. * 2011 with IB Witten, EE Steinberg, SY Lee, TJ Davidson, KA Zalocusky, M Brodsky, et al., ''Recombinase-driver rat lines: tools, techniques, and optogenetic application to dopamine-mediated reinforcement'', in: ''Neuron''. Vol. 72, nº 5; 721–733. * 2012 with LH Corbit, H Nie, ''Habitual alcohol seeking: time course and the contribution of subregions of the dorsal striatum'', in: ''Biological Psychiatry''. Vol. 72, nº 5; 389–395. * 2004 with NNH McGough, DY He, ML Logrip, J Jeanblanc, K Phamluong, K Luong, V Kharazia, D Ron, ''RACK1 and brain-derived neurotrophic factor: a homeostatic pathway that regulates alcohol addiction'', in: ''Journal of Neuroscience''. Vol. 24, nº 46; 10542–10552. * 2015 with R Keiflin, ''Dopamine prediction errors in reward learning and addiction: from theory to neural circuitry'', in: ''Neuron''. Vol. 88, nº 2; 247–263.

==References== {{reflist}}

==External links== * [https://web.archive.org/web/20150719023538/http://pbs.jhu.edu/research/janak/facultyinfo/ Webpage at Johns Hopkins University] * [http://neuroscience.jhu.edu/resources/directory/faculty/patricia-janak/ Neuroscience webpage at Johns Hopkins University] * [http://scienceoflearning.jhu.edu/ Johns Hopkins Science of Learning Institute] {{Webarchive|url=https://web.archive.org/web/20150405130101/http://scienceoflearning.jhu.edu/ |date=2015-04-05 }}

{{DEFAULTSORT:Janak, Patricia}} Category:American neuroscientists Category:American women neuroscientists Category:Johns Hopkins University faculty Category:Rutgers University alumni Category:University of California, Berkeley alumni Category:Wake Forest School of Medicine alumni Category:American clinical psychologists Category:Living people Category:1964 births Category:American women academics Category:21st-century American women scientists Category:21st-century American psychologists Category:American women psychologists Category:Fellows of the American Association for the Advancement of Science