{{Short description|Describes an impulse that runs along an axon away from the soma}} {{about|a type of neuronal impulse|orthodromic distance|great-circle distance}} {{Technical|date=September 2023}} An '''orthodromic impulse''' runs along an axon in its anterograde direction, away from the soma (cell body).<ref>{{cite journal|last=EYZAGUIRRE|first=C|author2=KUFFLER, SW|title=Further study of soma, dendrite, and axon excitation in single neurons.|journal=The Journal of General Physiology|date=Sep 20, 1955|volume=39|issue=1|pages=121–53|pmid=13252238|pmc=2147522|doi=10.1085/jgp.39.1.121}}</ref>

In the heart, orthodromic may also refer to an impulse going from the atria to the ventricles through the AV node, in contrast to some impulses in re-entry that go from the atria to the ventricles through an anomalous accessory pathway (antidromic conduction through de AV node). This is relevant in the differential diagnosis of supraventricular tachycardia, mainly AV re-entrant tachycardia.<ref>{{Citation |last=Katritsis |first=Demosthenes G |title=Wolff-Parkinson-White syndrome and atrioventricular reentrant tachycardias |date=2022 |work=Clinical Cardiac Electrophysiology |pages=276–305.e1 |url=https://linkinghub.elsevier.com/retrieve/pii/B9780323793384000248 |access-date=2025-08-27 |publisher=Elsevier |language=en |doi=10.1016/b978-0-323-79338-4.00024-8 |isbn=978-0-323-79338-4 |last2=Morady |first2=Fred|url-access=subscription }}</ref>

==See also== *Antidromic *Action potential *Anterograde tracing

==References== {{Reflist}}

Category:Neurophysiology

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