{{Short description|Mammalian protein found in Homo sapiens}} {{Infobox_gene}}

'''Solute carrier organic anion transporter family member 4C1''' is a protein that in humans is encoded by the SLCO4C1 gene, which is located on chromosome 5q21. The OATP4C1 protein is expressed in the basolateral membrane of the nephron of the human kidney, where it is involved in the uptake of organic anions for elimination in the urine. The drug digoxin is an important substrate of this transporter.<ref name="pmid14993604">{{cite journal |vauthors=Mikkaichi T, Suzuki T, Onogawa T, etal | title = Isolation and characterization of a digoxin transporter and its rat homologue expressed in the kidney | journal = Proc. Natl. Acad. Sci. U.S.A. | volume = 101 | issue = 10 | pages = 3569–74 |date=March 2004 | pmid = 14993604 | pmc = 373503 | doi = 10.1073/pnas.0304987101 | bibcode = 2004PNAS..101.3569M | doi-access = free }}</ref><ref name="entrez"> {{cite web | title = Entrez Gene: Solute carrier organic anion transporter family member 4C1 | url = https://www.ncbi.nlm.nih.gov/gene/353189 | accessdate = 2016-03-11 }}</ref>

==Function==

SLCO4C1 belongs to the organic anion transporter (OATP) family. OATPs are involved in the membrane transport of bile acids, conjugated steroids, thyroid hormone, eicosanoids, peptides, and numerous drugs in many tissues (Mikkaichi et al., 2004 [PubMed 14993604]).

== References ==

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== Further reading ==

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{{DEFAULTSORT:Oatp4c1}} Category:Solute carrier family Category:Transmembrane transporters Category:Human proteins Category: Thyroid hormone transporters