{{Short description|Protein-coding gene in the species Homo sapiens}} {{Infobox_gene}}
'''NLRP8''', short for NOD-like receptor family pyrin domain containing 8, is an intracellular protein that is expressed in the ovaries, testes, and preimplantation embryos of mammals.<ref name="pmid16339045">{{cite journal |vauthors=Ponsuksili S, Brunner RM, Goldammer T, etal |title=Bovine NALP5, NALP8, and NALP9 genes: assignment to a QTL region and the expression in adult tissues, oocytes, and preimplantation embryos |journal=Biol. Reprod. |volume=74 |issue=3 |pages=577–84 |date=March 2006 |pmid=16339045 |doi=10.1095/biolreprod.105.045096 |s2cid=2784688 |doi-access= }}</ref><ref name="pmid19682372">{{cite journal |vauthors=Tian X, Pascal G, Monget P |title=Evolution and functional divergence of NLRP genes in mammalian reproductive systems |journal=BMC Evol. Biol. |volume=9 |article-number=202 |year=2009 |issue=1 |pmid=19682372 |pmc=2735741 |doi=10.1186/1471-2148-9-202 |bibcode=2009BMCEE...9..202T |doi-access=free }}</ref> It is also known as NALP8, NOD16, PAN4, and CLR19.2, and is one of 14 pyrin domain containing members of the NOD-like receptor family of cytoplasmic receptors.
==References== {{Reflist}}
==Further reading== {{refbegin | 2}} *{{cite journal |vauthors=Enjuanes A, Benavente Y, Bosch F, etal |title=Genetic variants in apoptosis and immunoregulation-related genes are associated with risk of chronic lymphocytic leukemia. |journal=Cancer Res. |volume=68 |issue= 24 |pages= 10178–86 |year= 2008 |pmid= 19074885 |doi= 10.1158/0008-5472.CAN-08-2221 |doi-access= free |url= https://aacr.figshare.com/articles/journal_contribution/Supplementary_Figure_1_from_Genetic_Variants_in_Apoptosis_and_Immunoregulation-Related_Genes_Are_Associated_with_Risk_of_Chronic_Lymphocytic_Leukemia/22376466/1/files/39821778.pdf }} *{{cite journal |vauthors=Inohara N, Nuñez G |title=NODs: intracellular proteins involved in inflammation and apoptosis. |journal=Nat. Rev. Immunol. |volume=3 |issue= 5 |pages= 371–82 |year= 2003 |pmid= 12766759 |doi= 10.1038/nri1086 |s2cid=8088987 }} *{{cite journal |vauthors=Tschopp J, Martinon F, Burns K |title=NALPs: a novel protein family involved in inflammation. |journal=Nat. Rev. Mol. Cell Biol. |volume=4 |issue= 2 |pages= 95–104 |year= 2003 |pmid= 12563287 |doi= 10.1038/nrm1019 |s2cid=31417018 }} {{refend}}
{{NOD-like receptors}}
Category:LRR proteins Category:NOD-like receptors
{{Transmembranereceptor-stub}}