NEIL3

{{Short description|Protein-coding gene in the species Homo sapiens}} {{Infobox_gene}}

'''Nei endonuclease VIII-like 3 (E. coli)''' is a protein in humans that is encoded by the NEIL3 gene.<ref name="entrez">{{cite web | title = Entrez Gene: Nei endonuclease VIII-like 3 (E. coli) | url = https://www.ncbi.nlm.nih.gov/gene?db=gene&cmd=retrieve&list_uids=55247 }}</ref>

NEIL3 belongs to a class of DNA glycosylases homologous to the bacterial Fpg/Nei family. These glycosylases initiate the first step in base excision repair by cleaving bases damaged by reactive oxygen species and introducing a DNA strand break via the associated lyase reaction.<ref name="pmid12509226">{{cite journal |vauthors=Bandaru V, Sunkara S, Wallace SS, Bond JP | title = A novel human DNA glycosylase that removes oxidative DNA damage and is homologous to Escherichia coli endonuclease VIII | journal = DNA Repair (Amst.) | volume = 1 | issue = 7 | pages = 517–29 |date=July 2002 | pmid = 12509226 | doi = 10.1016/S1568-7864(02)00036-8 }}</ref>

== See also ==

* OGG1 * NTHL1 * NEIL1 * NEIL2

== References == {{reflist}}