D-Mycosamine
Iupacname3-Amino-3,6-dideoxy-β-D-mannopyranose
Othernames
  • * 3-amino-3,6-dideoxy-α-D-manno-hexopyranose
  • (2S,3S,4S,5S,6R)-4-amino-6-methyloxane-2,3,5-triol
  • 3-amino-3-desoxy-D-rhamnose

D-Mycosamine is an amino sugar found in several polyene antimycotics. Structural analogs of these agents lacking this monosaccharide component do not exhibit substantial antifungal activity.[1]

References

  1. ^ Nedal, A.; Sletta, H.; Brautaset, T.; Borgos, S. E. F.; Sekurova, O. N.; Ellingsen, T. E.; Zotchev, S. B. (17 December 2020). "Analysis of the Mycosamine Biosynthesis and Attachment Genes in the Nystatin Biosynthetic Gene Cluster of Streptomyces noursei ATCC 11455". Applied and Environmental Microbiology. 73 (22): 7400–7407. doi:10.1128/AEM.01122-07. PMC 2168226. PMID 17905880
  • Biosynthesis: [1]