Model 80 may refer to:
Aircraft
- Beech Model 80, a twin-piston-engine civil utility aircraft
- Boeing Model 80, an airliner introduced in 1982
- Fleet Model 80 Canuck, a civil utility aircraft introduced in 1946
- Stearman Model 80, a commercial biplane
Other
- Dana/Spicer Model 80, an automotive axle
- IBM PS/2 Model 80, a high-end member of the PS/2 family of personal computers