'''Mattox''' is a surname. Notable people with the surname include:
*Bain Mattox, American musician *Bernadette Mattox, American basketball coach *Cloy Mattox (1902–1985), American baseball player *Jim Mattox (1943–2008), American lawyer and politician *Jim Mattox (baseball) (1896–1973), American baseball player *Jon Mattox, American composer *Kenneth Mattox (born c. 1938), American surgeon *Martha Mattox (1879–1933), American actress *Marv Mattox, American football player *Matt Mattox (1922–2013), American jazz and ballet dancer *Ray Mattox (1927–2005), American politician
==See also== *Mattox Bastion, mountain of Antarctica *Mattox Creek, river in Virginia, United States
{{surname|Mattox}}