'''Masotti''' is an Italian surname. It loosely means ''son of Maso'', and the name ''Maso'' is derived from Tommaso, the Italian form of the name ''Thomas''.
Notable people with this surname include: * Baptiste Masotti (born 1995), French professional squash player * Fabio Masotti (born 1974), Italian amateur road and track cyclist * Ignazio Masotti (1817–1888), Italian cardinal * Paul Masotti (born 1965), Canadian football player
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