{{Short description|Italian physicist}}

{{Infobox scientist | name = Manlio De Domenico | birth_name = Manlio De Domenico | birth_date = 1984 <!-- Do not add flag icons to place of birth/death, per WP:FLAG -->| birth_place = Italy | death_date = | death_place = | other_names = | alma_mater = University of Catania <small>(Ph.D)</small> | citizenship = Italian |field = network science, multilayer networks, complex adaptive systems |work_institutions = University of Padua<br /> Fondazione Bruno Kessler<br />University of Rovira i Virgili<br />MPIPKS<br />University of Birmingham<br />Scuola superiore di Catania | years_active = | employer = | title = | boards = | spouse = | children = }}

'''Manlio De Domenico''' is an Italian physicist and complex systems scientist, currently Professor of Physics at the University of Padua and previously at the Fondazione Bruno Kessler in Trento (Italy). In 2014 he has co-founded the Mediterranean School of Complex Networks,<ref>{{cite web |title=MSCX.net: Mediterranean School on Complex Networks |url=https://mediterraneanschoolcomplex.net/}}</ref> and in 2019 he has contributed to found the Italian Chapter of the Complex Systems Society, for which he served as first President.<ref>{{cite web |title=CSS/Italy |url=http://italy.cssociety.org/}}</ref>

The focus of his research is on complex adaptive systems and big data analysis, where he is best known for his theoretical and computational work in network science, statistical physics and nonlinear dynamics of multilayer systems<ref name="DeDomenico_mathematical">{{cite journal |last1=De Domenico |first1=Manlio |last2=Solé-Ribalta |first2=Albert |last3=Cozzo |first3=Emanuele |last4=Kivelä |first4=Mikko |last5=Moreno |first5=Yamir |last6=Porter |first6=Mason A. |last7=Gómez |first7=Sergio |last8=Arenas |first8=Alex |date=December 2013 |title=Mathematical Formulation of Multilayer Networks |url=https://journals.aps.org/prx/abstract/10.1103/PhysRevX.3.041022 |journal=Physical Review X |volume=3 |issue=4 |arxiv=1307.4977 |doi=10.1103/PhysRevX.3.041022 |s2cid=16611157 |doi-access=free |article-number=041022}}</ref><ref name="DeDomenico_moreisdifferent">{{cite journal |last1=De Domenico |first1=Manlio |year=2023 |title=More is different in real-world multilayer networks |journal=Nature Physics |publisher=Springer Nature |volume=19 |pages=1247–1262 |doi=10.1038/s41567-023-02132-1 |issn=1745-2473}}</ref>.

==Early life and education==

He was born in Messina in 1984. He got his Ph.D. in nuclear and astroparticle physics from the University of Catania and the Scuola Superiore di Catania in 2012, proposing a data-driven model for the propagation of Ultra-High Energy Cosmic Rays (UHECR) in a magnetized Universe and a multiscale approach to analyze their anisotropic distribution at Earth,<ref>{{cite thesis |last1=De Domenico |first1=Manlio |title=Propagation of Ultra-high energy cosmic rays and anisotropy studies with the Pierre Auger Observatory: the multiscale approach |citeseerx=10.1.1.712.3911 |degree=PhD |s2cid=124477418}}</ref> with visiting scholarships at the Institute for Nuclear Theory<ref>{{cite web |title=Institute for Nuclear Theory |url=https://sites.google.com/uw.edu/int/home |access-date=1 October 2021}}</ref> of the University of Washington and the Institut de physique nucléaire d'Orsay.

==Career and research==

He held postdoctoral positions (2012-2013) at the School of Computer Science of the University of Birmingham (UK), and (2013-2016) at the University of Rovira i Virgili (Spain). In 2016 he has been a visiting scholar at the Max Planck Institute for the Physics of Complex Systems. From 2016 to 2018 he held the "Juan de la Cierva" senior fellowship at the University of Rovira i Virgili. Since 2018 he directs the Complex Multilayer Networks (CoMuNe) Lab<ref>{{cite web |title=CoMuNe Lab |url=https://manliodedomenico.com/people.php|access-date=1 October 2021}}</ref> founded at the Fondazione Bruno Kessler.

He has published more than 190 scientific papers,<ref>{{cite web |title=M. De Domenico on Scopus |url=https://www.scopus.com/authid/detail.uri?authorId=26537490500 |access-date=1 January 2025}}</ref> with interdisciplinary contributions in computational social science, network epidemiology, network neuroscience, network medicine and systems biology. Notable works include the tensorial formulation of multilayer structure and dynamics,<ref name="DeDomenico_mathematical" /><ref name="DeDomenico_physics">{{cite journal | last1=De Domenico | first1=Manlio | last2=Granell | first2=Clara | last3=Porter | first3=Mason A. | last4=Arenas | first4=Alex | title=The physics of spreading processes in multilayer networks | journal=Nature Physics | publisher=Springer Science and Business Media LLC | volume=12 | issue=10 | date=2016-08-22 | issn=1745-2473 | doi=10.1038/nphys3865 | pages=901–906| arxiv=1604.02021 | s2cid=5063264 }}</ref><ref name="DeDomenico_more">{{cite journal | last1=De Domenico | first1=Manlio | title=More is different in real-world multilayer networks | journal=Nature Physics | publisher=Springer Science and Business Media LLC | volume=19 | date=2023-08-28 | issn=1745-2473 | doi=10.1038/s41567-023-02132-1 | pages=1247-1262}}</ref> applications to community structure<ref name="DeDomenico_modular">{{cite journal | last1=De Domenico | first1=Manlio | last2=Lancichinetti | first2=Andrea | last3=Arenas | first3=Alex | last4=Rosvall | first4=Martin | title=Identifying Modular Flows on Multilayer Networks Reveals Highly Overlapping Organization in Interconnected Systems | journal=Physical Review X | volume=5 | issue=1 | date=2015-03-06 | issn=2160-3308 | doi=10.1103/physrevx.5.011027 | article-number=011027| arxiv=1408.2925 | s2cid=6364922 }}</ref> and coupling of human behavior with epidemic spreading,<ref name="Poletti_measles">{{cite journal | last1=Bosetti | first1=Paolo | last2=Poletti | first2=Piero | last3=Stella | first3=Massimo | last4=Lepri | first4=Bruno | last5=Merler | first5=Stefano | last6=De Domenico | first6=Manlio | title=Heterogeneity in social and epidemiological factors determines the risk of measles outbreaks | journal=Proceedings of the National Academy of Sciences | volume=117 | issue=48 | date=2020 | doi=10.1073/pnas.1920986117 | pages=30118–30125| pmid=33203683 | pmc=7720222 | doi-access=free }}</ref> network geometry,<ref name="DeDomenico_diffusion">{{cite journal | last=De Domenico | first=Manlio | title=Diffusion Geometry Unravels the Emergence of Functional Clusters in Collective Phenomena | journal=Physical Review Letters | volume=118 | issue=16 | date=2017-04-17 | issn=0031-9007 | doi=10.1103/physrevlett.118.168301 | article-number= 168301| pmid=28474920 | arxiv=1704.07068 | s2cid=2638868 }}</ref><ref name="BogunaBonamassaDeDomenico">{{cite journal | last1=Boguñá | first1=Marián | last2=Bonamassa | first2=Ivan | last3=De Domenico | first3=Manlio | last4=Havlin | first4=Shlomo | last5=Krioukov | first5=Dmitri | last6=Serrano | first6=M. Ángeles |author6-link=M. Ángeles Serrano| title=Network geometry | journal=Nature Reviews Physics | publisher=Springer Science and Business Media LLC | volume=3 | issue=2 | date=2021-01-29 | issn=2522-5820 | doi=10.1038/s42254-020-00264-4 | pages=114–135| arxiv=2001.03241 | s2cid=210157073 }}</ref> network entropy for multiscale analysis of the interplay between structure and dynamics,<ref name="DeDomenico_entropy">{{cite journal | last1=De Domenico | first1=Manlio | last2=Biamonte | first2=Jacob | title=Spectral entropies as information-theoretic tools for complex network comparison | journal=Physical Review X | volume=6 | issue=4 | date=2016-11-01 | issn= | doi=10.1103/PhysRevX.6.041062 | article-number=041062| arxiv=1609.01214 | s2cid=51786781 }}</ref><ref name="Ghavasieh_DeDomenico_sparsity">{{cite journal | last1=Ghavasieh | first1=Arsham | last2=De Domenico | first2=Manlio | title=Diversity of information pathways drives sparsity in real-world networks | journal=Nature Physics | volume=20 | pages=512–519 | year=2024 | publisher=Springer Nature | doi=10.1038/s41567-023-02330-x | issn=1745-2473}}</ref>, percolation and network robustness to perturbations,<ref name="DeDomenico_navigability">{{cite journal | last1=De Domenico | first1=M. | last2=Sole-Ribalta | first2=A. | last3=Gomez | first3=S. | last4=Arenas | first4=A. | title=Navigability of interconnected networks under random failures | journal=Proceedings of the National Academy of Sciences | volume=111 | issue=23 | date=2014-05-27 | issn=0027-8424 | doi=10.1073/pnas.1318469111 | pages=8351–8356| pmid=24912174 | pmc=4060702 | doi-access=free }}</ref><ref name="Artime_percolation">{{cite journal | last1=Artime | first1=Oriol | last2=De Domenico | first2=Manlio | title= Percolation on feature-enriched interconnected systems | journal=Nature Communications | volume=12 | issue=1 | date=2021-04-30 | issn= 2041-1723 | doi=10.1038/s41467-021-22721-z | arxiv=2104.14893 | page=2478| pmid=33931643 | pmc=8087700 }}</ref><ref name="Grassia_early">{{cite journal | last1=Grassia | first1=Marco | last2=Mangioni | first2=Giuseppe | last3=De Domenico | first3=Manlio | title= Machine learning dismantling and early-warning signals of disintegration in complex systems | journal=Nature Communications | volume=12 | issue=23 | date=2021-08-31 | issn= 2041-1723 | doi=10.1038/s41467-021-25485-8|arxiv=2101.02453 | page=5190| pmid=34465786 | pmc=8408155 }}</ref><ref>{{Cite journal |last=Artime |first=Oriol |last2=Grassia |first2=Marco |last3=De Domenico |first3=Manlio |last4=Gleeson |first4=James P. |last5=Makse |first5=Hernán A. |last6=Mangioni |first6=Giuseppe |last7=Perc |first7=Matjaž |last8=Radicchi |first8=Filippo |date=2024-01-08 |title=Robustness and resilience of complex networks |url=https://www.nature.com/articles/s42254-023-00676-y |journal=Nature Reviews Physics |language=en |pages=1–18 |doi=10.1038/s42254-023-00676-y |issn=2522-5820|hdl=11577/3505699 |hdl-access=free |arxiv=2509.19867 }}</ref>, Infodemic<ref name="Gallotti_infodemic">{{cite journal | last1=Gallotti | first1=Riccardo | last2=Valle | first2=Francesco | last3=Castaldo | first3=Nicola | last4=Sacco | first4=Pierluigi | last5=De Domenico | first5=Manlio | title=Assessing the risks of 'infodemics' in response to COVID-19 epidemics | journal=Nature Human Behaviour | publisher=Springer Science and Business Media LLC | volume=4 | issue=12 | date=2020-10-29 | issn=2397-3374 | doi=10.1038/s41562-020-00994-6 | pages=1285–1293| pmid=33122812 | arxiv=2004.03997 | s2cid=226206314 }}</ref><ref>{{cite web |title=Covid19 Infodemics Observatory |url=https://covid19obs.fbk.eu/#/ |access-date=1 October 2021}}</ref>, and digital twin methods for precision medicine.<ref name="DeDomenico_digitaltwin">{{cite journal | last1=De Domenico | first1=Manlio | last2=Allegri | first2=Luca | last3=Caldarelli | first3=Guido | last4=d'Andrea | first4=Valeria | last5=Di Camillo | first5=Barbara | last6=Rocha | first6=Luis M. | last7=Rozum | first7=Jordan | last8=Sbarbati | first8=Riccardo | last9=Zambelli | first9=Francesco | title=Challenges and opportunities for digital twins in precision medicine from a complex systems perspective | journal=npj Digital Medicine | volume=8 | year=2025 | publisher=Springer Nature | doi=10.1038/s41746-024-01402-3 | issn=2398-6352| pmc=11742446 }}</ref>

His work also includes studies of the architecture of living systems<ref name="DeDomenico_architecture">{{cite journal | last1=De Domenico | first1=Manlio | title=Decoding the architecture of living systems | journal=Reports on Progress in Physics | volume=89 | page=014601 | year=2026 | publisher=IOP Publishing | doi=10.1088/1361-6633/ae2ca2 | arxiv=2512.22651 }}</ref>, bifurcations and phase transitions in the origins of life<ref name="Sole_constraints">{{cite journal | last1=Solé | first1=R. | last2=Kempes | first2=C. P. | last3=Corominas-Murtra | first3=B. | last4=De Domenico | first4=M. | last5=Kolchinsky | first5=A. | last6=Lachmann | first6=M. | last7=Libby | first7=E. | last8=Saavedra | first8=S. | last9=Smith | first9=E. | last10=Wolpert | first10=D. | title=Fundamental constraints to the logic of living systems | journal=Interface Focus | volume=14 | issue=5 | article-number=20240010 | year=2024 | publisher=The Royal Society | doi=10.1098/rsfs.2024.0010 | pmid=39464646 | hdl=10261/374533 | hdl-access=free }}</ref> and fundamental physical and informational constraints shaping the logic of living systems<ref name="Sole_originsoflife">{{cite journal | last1=Solé | first1=R. | last2=De Domenico | first2=M. | title=Bifurcations and phase transitions in the origins of life | journal=Philosophical Transactions of the Royal Society B: Biological Sciences | volume=380 | issue=1936 | article-number=20240295 | year=2025 | publisher=The Royal Society | doi=10.1098/rstb.2024.0295 }}</ref>.

His collaborators include Alex Arenas, Marc Barthelemy, Sylvie Briand, Guido Caldarelli, James Cronin, Shlomo Havlin, Vito Latora, Yamir Moreno, Mason Porter, Steven Strogatz and Alan Andrew Watson.

==Awards and honours==

In 2023, he [https://www.mur.gov.it/it/news/lunedi-31072023/ricerca-47-le-proposte-deccellenza-selezionate-il-fondo-italiano-la-scienza was awarded a significant grant] from the ''Fondo Italiano per la Scienza'' (FIS) of the Italian Ministry of University and Research, distinguishing himself as one of 47 exceptional scientists selected from 1,912 applicants. This grant provides substantial research funding aimed at developing optimal strategies for adapting human-made systems and networks to the current and future effects of climate change, addressing key challenges at the intersection of complex systems science and environmental change.

Other awards and recognitions:

* 2020: ''Young Scientist Award for Socio- and Econophysics'', from the German Physical Society<ref>{{cite web |title=Young Scientist Award for Socio- and Econophysics |url=https://www.dpg-physik.de/vereinigungen/fachlich/skm/fvsoe/young-scientist-award |access-date=1 October 2021}}</ref> for Multilayer modeling and analysis of complex socio-economic systems<ref>{{cite web |title=Young Scientist Award for Socio- and Econophysics - 2020 |url=https://dresden20.dpg-tagungen.de/programm/young-academic-awards?set_language=en&cl=en}}</ref> * 2019: ''IUPAP Young Scientist Award on Statistical Physics'', from the International Union of Pure and Applied Physics C3 commission, for Interdisciplinary Applications of Statistical Physics<ref>{{cite web |title=IUPAP-C3 Young Scientist Award on Statistical Physics |date=8 March 2021 |url=https://iupap.org/who-we-are/internal-organization/commissions/c3-statistical-physics/c3-news/ |access-date=1 October 2021}}</ref> * 2017: USERN Prize in Formal Sciences, from USERN, for modeling the complexity of systems of systems * 2016: ''Junior Scientific Award'', from the Complex Systems Society, for a number of pioneering contributions to the field of multilayer networks<ref>{{cite web |title=Junior scientific award - CCS |url=https://cssociety.org/community/css-awards |access-date=1 October 2021}}</ref> * 2012: ''Bruno Rossi Prize'', from the Istituto Nazionale di Fisica Nucleare (INFN) for the Best Italian PhD thesis in Nuclear and Astroparticle Physics<ref>{{cite web |title=INFN Prizes 2013 |url=https://web.infn.it/csn2/images/Files/Verbali/verbaleCSN2_Aprile2013.pdf}}</ref>

==Trivia==

His influential article, ''Complesso è diverso da complicato: per questo serve multidisciplinarietà,'' which discusses the difference between complex and complicated systems and argues for the importance of multidisciplinarity, was featured in ''Il Sole 24 Ore'' (Nòva supplement, 6 March 2022, p. 18). This piece was selected by the Italian Ministry of Education as one of the three texts for the 2022 supplementary session of the upper secondary education Italian exams, alongside works by W. Churchill and Philippe Daverio. [External Link to the Italian Exam Document](https://www.istruzione.it/esame_di_stato/202122/Italiano/Suppletiva/P000_SUP22.pdf)

==References== {{reflist}}

==External links== *{{Google Scholar id | KhJ4UFIAAAAJ }}

{{authority control}} {{DEFAULTSORT:De Domenico, Manlio}}

Category:1984 births Category:Living people Category:Italian physicists Category:University of Catania alumni