| Ec number | 3.5.1.86 |
|---|---|
| Go code | 0050537 |
In enzymology, a mandelamide amidase () is an enzyme that catalyzes the chemical reaction
- (R)-mandelamide + H2O
\rightleftharpoons(R)-mandelate + NH3
Thus, the two substrates of this enzyme are (R)-mandelamide and H2O, whereas its two products are (R)-mandelate and NH3.
This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in linear amides. The systematic name of this enzyme class is mandelamide hydrolase. This enzyme is also called Pseudomonas mandelamide hydrolase.
References
- Yamamoto K, Oishi K, Fujimatsu I, Komatsu K (1991). "Production of R-(−)-mandelic acid from mandelonitrile by Alcaligenes faecalis ATCC 8750". Appl. Environ. Microbiol.. 57 (10): 3028–32. Bibcode:1991ApEnM..57.3028Y. doi:10.1128/aem.57.10.3028-3032.1991. PMC 183915. PMID 1660699