{{chembox | Name = MOPSO | ImageFile = MOPSO.png | ImageName = Chemical structure of MOPSO | PIN = 2-Hydroxy-3-(morpholin-4-yl)propane-1-sulfonic acid<ref>{{cite web| title=Compound Summary for CID 109333| website=PubChem| date=2005-03-27| url=https://pubchem.ncbi.nlm.nih.gov/compound/Mopso#section=Top}}</ref><ref>{{cite web| title=MOPSO| website=Sigma-Aldrich| url=http://www.sigmaaldrich.com/catalog/product/sigma/m8389?lang=en&region=US }}</ref> | OtherNames = MOPSO, 3-morpholino-2-hydroxypropanesulfonic acid, 3-morpholino-2HOPSA |Section1={{Chembox Identifiers | CASNo = 68399-77-9 | CASNo_Ref = {{Cascite|correct|CAS}} | ChEBI = 190979 | ChemSpiderID = 98300 | UNII_Ref = {{fdacite|correct|FDA}} | UNII = 6XB7PS9THL | EINECS = 269-989-6 | PubChem = 109333 | InChI = 1S/C7H15NO5S/c9-7(6-14(10,11)12)5-8-1-3-13-4-2-8/h7,9H,1-6H2,(H,10,11,12) | InChIKey = NUFBIAUZAMHTSP-UHFFFAOYSA-N | SMILES = C1COCCN1CC(CS(=O)(=O)O)O }} | Section2 = {{Chembox Properties | C=7 | H=15 | N=1 | O=5 | S=1 | MolarMass = 225.259 g/mol | Appearance = White crystalline powder | MeltingPtC = 270-290 | pKa = 6.9<ref>{{cite web| title=Biological Buffers| website=Sigma-Aldrich| url=http://www.sigmaaldrich.com/life-science/metabolomics/bioultra-reagents/biological-buffers.html}}</ref> }} | Section3 = {{Chembox Hazards | MainHazards = Irritant | FlashPt = Non-flammable | GHS_ref= [https://pubchem.ncbi.nlm.nih.gov/compound/109333#section=Safety-and-Hazards] | GHSPictograms = {{GHS07}} | GHSSignalWord = Warning | HPhrases = {{H-phrases|315|319|335}} | PPhrases = {{P-phrases|261|264|271|280|302+352|304+340|305+351+338|312|321|332+313|337+313|362|403+233|405|501}} }} }}

'''MOPSO''' is a zwitterionic organic chemical buffering agent; one of Good's buffers. MOPSO and MOPS (3-morpholinopropanesulfonic acid) are chemically similar, differing only in the presence of a hydroxyl group on the C-2 of the propane moiety. It has a useful pH range of 6.5-7.9 in the physiological range, making it useful for cell culture work. It has a pKa of 6.9 with ΔpKa/°C of -0.015 and a solubility in water at 0°C of 0.75 M.

MOPSO has been used as a buffer component for:<ref>{{cite web| title=MOPSO sodium salt| website=Sigma-Aldrich| url=https://www.sigmaaldrich.com/content/dam/sigma-aldrich/docs/Sigma/Product_Information_Sheet/1/m8767pis.pdf}}</ref> * Copper analysis via: ** Flow injection micellar technique of the catalytic reaction of 3-methyl-2-benzothiazolinone hydrazone and N-ethyl-N-(2-hydroxy-3-sulfopropyl)-3,5-dimethoxyaniline ** Electrospray ionization quadrupole time-of-flight mass spectroscopy to measure MOPSO-copper chelated complexes * Discontinuous gel electrophoresis on rehydratable polyacrylamide gels * Buffered charcoal yeast extract agar * Fixing cells in urine in a buffered alcohol * Testing crude oil bioremediation products in marine environments

==See also== * MOPS * MES * CAPS * CHES

==References== {{reflist}}

{{DEFAULTSORT:Hydroxy-3-morpholinopropanesulfonic acid, 2-}} Category:Zwitterions Category:4-Morpholinyl compounds Category:Sulfonic acids Category:Secondary alcohols